The study of B→J/Ψη(′)B\to J/\Psi \eta^{(\prime)} decays and determination of η−η′\eta-\eta^{\prime} mixing angle

We study $B\to J/\Psi \eta^{(\prime)}$ decays and suggest two methods to determine the $\eta-\eta^{\prime}$ mixing angle. We calculate not only the factorizable contribution in QCD facorization scheme but also the nonfactorizable hard spectator corrections in pQCD approach. We get the branching ratio of $B\to J/\Psi \eta$ which is consistent with recent experimental data and predict the branching ratio of $B\to J/\Psi \eta^{\prime}$ to be $7.59\times 10^{-6}$. Two methods for determining $\eta-\eta^{\prime}$ mixing angle are suggested in this paper. For the first method, we get the $\eta-\eta^{\prime}$ mixing angle to be about $-13.1^{\circ}$, which is in consistency with others in the literature. The second method depends on less parameters so can be used to determine the $\eta-\eta^{\prime}$ mixing angle with better accuracy but needs, as an input, the branching ratio for $B\to J/\Psi \eta^{\prime}$which should be measured in the near future.Comment: 16pages,4figure

Assessment of treatment response in tuberculosis

Antibiotic treatment of tuberculosis has a duration of several months. There is significant variability of the host immune response and the pharmacokinetic-pharmacodynamic properties of Mycobacterium tuberculosis sub-populations at the site of disease. A limitation of sputum-based measures of treatment response may be sub-optimal detection and monitoring of Mycobacterium tuberculosis sub-populations. Potential biomarkers and surrogate endpoints should be benchmarked against hard clinical outcomes (failure/relapse/death) and may need tailoring to specific patient populations. Here, we assess the evidence supporting currently utilized and future potential host and pathogen-based models and biomarkers for monitoring treatment response in active and latent tuberculosis. Biomarkers for monitoring treatment response in extrapulmonary, pediatric and drug resistant tuberculosis are research priorities

Dynamical Behavior of a stochastic SIRS epidemic model

In this paper we study the Kernack - MacKendrick model under telegraph noise. The telegraph noise switches at random between two SIRS models. We give out conditions for the persistence of the disease and the stability of a disease free equilibrium. We show that the asymptotic behavior highly depends on the value of a threshold $\lambda$ which is calculated from the intensities of switching between environmental states, the total size of the population as well as the parameters of both SIRS systems. According to the value of $\lambda$, the system can globally tend towards an endemic case or a disease free case. The aim of this work is also to describe completely the omega-limit set of all positive solutions to the model. Moreover, the attraction of the omega-limit set and the stationary distribution of solutions will be pointed out.Comment: 16 page

Recent results in Euclidean dynamical triangulations

We study a formulation of lattice gravity defined via Euclidean dynamical triangulations (EDT). After fine-tuning a non-trivial local measure term we find evidence that four-dimensional, semi-classical geometries are recovered at long distance scales in the continuum limit. Furthermore, we find that the spectral dimension at short distance scales is consistent with 3/2, a value that is also observed in the causal dynamical triangulation (CDT) approach to quantum gravity.Comment: 7 pages, 3 figures. Proceedings for the 3rd conference of the Polish society on relativit

An unusual cause of gynaecomastia in a male

Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation. However, it is also secreted in varying amounts in non-pregnant conditions commonly heralding a neoplastic process. We present a case of 50-year-old man, who presented with bilateral gynaecomastia with elevated testosterone, oestradiol, suppressed gonadotropins with progressively increasing levels of human chorionic gonadotropin (hCG). Biochemical and radiological investigations including ultrasonography of testes, breast tissue, MRI pituitary and CT scan full body did not identify the source of hCG. FDG PET scan revealed a large mediastinal mass with lung metastasis. Immunostaining and histological analysis confirmed the diagnosis of primary choriocarcinoma of the mediastinum. It is highly aggressive and malignant tumor with poor prognosis. Early diagnosis and management are essential for the best outcome. Learning Points: High βhCG in a male patient or a non-pregnant female suggests a paraneoplastic syndrome. In the case of persistently positive serum hCG, exclude immunoassay interference by doing the urine hCG as heterophilic antibodies are not present in the urine. Non-gestational choriocarcinoma is an extremely rare trophoblastic tumor and should be considered in young men presenting with gynaecomastia and high concentration of hCG with normal gonads. A high index of suspicion and extensive investigations are required to establish an early diagnosis of extra-gonadal choriocarcinoma. Early diagnosis is crucial to formulate optimal management strategy and to minimize widespread metastasis for best clinical outcome

Power Corrections in Charmless B Decays

In this paper, we focus on the role of power corrections in QCD factorization(QCDF) method in charmless two-body nonleptonic $B$ meson decays. We use the ratio of the branching fraction of $B^+ \to \pi^+ K^{\ast 0}$ to that of $B^0 \to \pi^- \rho^+$, for which the theoretical uncertainties are greatly reduced, to show clearly that the power corrections in charmless B decays are probably large. With other similar ratios considered, for example, for the $B^0 \to K^- \rho^+$ decay, it is very likely that, among various sources of power corrections, annihilation topology plays an indispensable role at least for penguin dominated $\rm PV$ channels. We also consider some selective ratios of direct CP asymmetries. Among these, we find that, if power corrections other than the chirally enhanced power corrections and annihilation topology were negligible, QCDF would predict the direct CP asymmetry of $B \to \pi^+ \pi^-$ to be about 3 times larger than that of $B \to \pi^\pm K^\mp$, with opposite sign. Experimentally any significant deviation from this prediction would suggest either new physics or possibly the importance of long-distance rescattering effects.Comment: references and note added, to appear in Phys. Rev.