'The effect of different genres of music on the stress levels of kennelled dogs'

Classical music has been shown to reduce stress in kennelled dogs; however, rapid habituation of dogs to this form of auditory enrichment has also been demonstrated. The current study investigated the physiological and behavioural response of kennelled dogs (n = 38) to medium-term (5 days) auditory enrichment with five different genres of music including Soft Rock, Motown, Pop, Reggae and Classical, to determine whether increasing the variety of auditory stimulation reduces the level of habituation to auditory enrichment. Dogs were found to spend significantly more time lying and significantly less time standing when music was played, regardless of genre. There was no observable effect of music on barking, however, dogs were significantly (z = 2.2, P < 0.05) more likely to bark following cessation of auditory enrichment. Heart Rate Variability (HRV) was significantly higher, indicative of decreased stress, when dogs were played Soft Rock and Reggae, with a lesser effect observed when Motown, Pop and Classical genres were played. Relative to the silent period prior to auditory enrichment, urinary cortisol:creatanine (UCCR) values were significantly higher during Soft Rock (t = 2.781, P < 0.01) and the second silent control period following auditory enrichment (t = 2.46, P < 0.05). Despite the mixed response to different genres, the physiological and behavioural changes observed remained constant over the 5d of enrichment suggesting that the effect of habituation may be reduced by increasing the variety of auditory enrichment provided

State and Local Government Legal Responsibilities to Provide Medical Care for the Poor

This article will provide an overview of the extent to which state and local government entities must provide medical care for the poor and ways to enforce these obligations. Delineation of specific medical assistance program responsibilities requires careful review of the legislative intent and statutory purpose. Remedies for state or local failure to meet statutory or constitutional obligations to provide indigent medical care will be discussed in the enforcement section

State and Local Government Legal Responsibilities to Provide Medical Care for the Poor

This article will provide an overview of the extent to which state and local government entities must provide medical care for the poor and ways to enforce these obligations. Delineation of specific medical assistance program responsibilities requires careful review of the legislative intent and statutory purpose. Remedies for state or local failure to meet statutory or constitutional obligations to provide indigent medical care will be discussed in the enforcement section

Improving proactive decision making with object trend displays

Operators of dynamic systems often use time-series data to support their diagnostic and proactive decision-making. Those data have traditionally been displayed in the form of separate trend charts, for example, line graphs of pressure and temperature over time. Configural object displays are a widely advocated approach to the visual integration of information yet have been applied only rarely to time-series data. One example was the 'time tunnel' format but its benefits were equivocal, seemingly compromised by its graphical complexity. There is then the need to investigate other graphical forms for object displays of time series data. This research will require a microworld representing a knowledge-rich task domain accessible to multiple participants (the nuclear power plant simulation used with the time tunnel display studies required participants to have 20 hours of experience with the system). We report a design for such a microworld that adopts the domain of financial control of a business where decisions need to be made about the pricing of products to optimize returns in a changing and sometimes volatile market. Alternative visual displays of the essential time series data for this domain are possible and whilst decision making is knowledge rich, involving reasoning about high level relationships, pilot tests showed that it is accessible to participants with only moderate training

Dynamical Structure of the Molecular Interstellar Medium in an Extremely Bright, Multiply Lensed z ≃ 3 Submillimeter Galaxy Discovered with Herschel

We report the detection of CO(J = 5 → 4), CO(J = 3 → 2), and CO(J = 1 → 0) emission in the strongly lensed, Herschel/SPIRE-selected submillimeter galaxy (SMG) HERMES J105751.1+573027 at z = 2.9574 ± 0.0001, using the Plateau de Bure Interferometer, the Combined Array for Research in Millimeter-wave Astronomy, and the Green Bank Telescope. The observations spatially resolve the molecular gas into four lensed images with a maximum separation of ~9" and reveal the internal gas dynamics in this system. We derive lensing-corrected CO line luminosities of L'_(CO(1-0)) = (4.17 ± 0.41), L'_(CO(3-2)) = (3.96 ± 0.20), and L'_(CO(5-4)) = (3.45 ± 0.20) × 10^(10) (μL/10.9)^(–1) K km s^(–1) pc^2, corresponding to luminosity ratios of r_(31) = 0.95 ± 0.10, r_(53) = 0.87 ± 0.06, and r_(51) = 0.83 ± 0.09. This suggests a total molecular gas mass of M_(gas) = 3.3×10^(10) (α_(CO)/0.8) (μ_L/10.9)^(–1) M_☉. The gas mass, gas mass fraction, gas depletion timescale, star formation efficiency, and specific star formation rate are typical for an SMG. The velocity structure of the gas reservoir suggests that the brightest two lensed images are dynamically resolved projections of the same dust-obscured region in the galaxy that are kinematically offset from the unresolved fainter images. The resolved kinematics appear consistent with the complex velocity structure observed in major, "wet" (i.e., gas-rich) mergers. Major mergers are commonly observed in SMGs and are likely to be responsible for fueling their intense starbursts at high gas consumption rates. This study demonstrates the level of detail to which galaxies in the early universe can be studied by utilizing the increase in effective spatial resolution and sensitivity provided by gravitational lensing

VisGenome: visualization of single and comparative genome representations

VisGenome visualizes single and comparative representations for the rat, the mouse and the human chromosomes at different levels of detail. The tool offers smooth zooming and panning which is more flexible than seen in other browsers. It presents information available in Ensembl for single chromosomes, as well as homologies (orthologue predictions including ortholog one2one, apparent ortholog one2one, ortholog many2many) for any two chromosomes from different species. The application can query supporting data from Ensembl by invoking a link in a browser

Scanamorphos: a map-making software for Herschel and similar scanning bolometer arrays

Scanamorphos is one of the public softwares available to post-process scan observations performed with the Herschel photometer arrays. This post-processing mainly consists in subtracting the total low-frequency noise (both its thermal and non-thermal components), masking high-frequency artefacts such as cosmic ray hits, and projecting the data onto a map. Although it was developed for Herschel, it is also applicable with minimal adjustment to scan observations made with some other imaging arrays subjected to low-frequency noise, provided they entail sufficient redundancy; it was successfully applied to P-Artemis, an instrument operating on the APEX telescope. Contrary to matrix-inversion softwares and high-pass filters, Scanamorphos does not assume any particular noise model, and does not apply any Fourier-space filtering to the data, but is an empirical tool using purely the redundancy built in the observations -- taking advantage of the fact that each portion of the sky is sampled at multiple times by multiple bolometers. It is an interactive software in the sense that the user is allowed to optionally visualize and control results at each intermediate step, but the processing is fully automated. This paper describes the principles and algorithm of Scanamorphos and presents several examples of application.Comment: This is the final version as accepted by PASP (on July 27, 2013). A copy with much better-quality figures is available on http://www2.iap.fr/users/roussel/herschel

Evaluating RNAlater® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species.

Mosquito age and species identification is a crucial determinant of the efficacy of vector control programmes. Near-infrared spectroscopy (NIRS) has previously been applied successfully to rapidly, non-destructively, and simultaneously determine the age and species of freshly anesthetized African malaria vectors from the Anopheles gambiae s.l. species complex: An. gambiae s. s. and Anopheles arabiensis. However, this has only been achieved on freshly-collected specimens and future applications will require samples to be preserved between field collections and scanning by NIRS. In this study, a sample preservation method (RNAlater(®)) was evaluated for mosquito age and species identification by NIRS against scans of fresh samples. Two strains of An. gambiae s.s. (CDC and G3) and two strains of An. arabiensis (Dongola, KGB) were reared in the laboratory while the third strain of An. arabiensis (Ifakara) was reared in a semi-field system. All mosquitoes were scanned when fresh and rescanned after preservation in RNAlater(®) for several weeks. Age and species identification was determined using a cross-validation. The mean accuracy obtained for predicting the age of young (<7 days) or old (≥ 7 days) of all fresh (n = 633) and all preserved (n = 691) mosquito samples using the cross-validation technique was 83% and 90%, respectively. For species identification, accuracies were 82% for fresh against 80% for RNAlater(®) preserved. For both analyses, preserving mosquitoes in RNAlater(®) was associated with a highly significant reduction in the likelihood of a misclassification of mosquitoes as young or old using NIRS. Important to note is that the costs for preserving mosquito specimens with RNAlater(®) ranges from 3-13 cents per insect depending on the size of the tube used and the number of specimens pooled in one tube. RNAlater(®) can be used to preserve mosquitoes for subsequent scanning and analysis by NIRS to determine their age and species with minimal costs and with accuracy similar to that achieved from fresh insects. Cold storage availability allows samples to be stored longer than a week after field collection. Further study to develop robust calibrations applicable to other strains from diverse ecological settings is recommended

A Multi-Wavelength Study of Sgr A*: The Role of Near-IR Flares in Production of X-ray, Soft γ\gamma-ray and Sub-millimeter Emission

(abridged) We describe highlights of the results of two observing campaigns in 2004 to investigate the correlation of flare activity in Sgr A* in different wavelength regimes, using a total of nine ground and space-based telescopes. We report the detection of several new near-IR flares during the campaign based on {\it HST} observations. The level of near-IR flare activity can be as low as $\sim0.15$ mJy at 1.6 $\mu$m and continuous up to about 40% of the total observing time. Using the NICMOS instrument on the {\it HST}, the {\it XMM-Newton} and CSO observatories, we also detect simultaneous bright X-ray and near-IR flare in which we observe for the first time correlated substructures as well as simultaneous submillimeter and near-IR flaring. X-ray emission is arising from the population of near-IR-synchrotron-emitting relativistic particles which scatter submillimeter seed photons within the inner 10 Schwarzschild radii of Sgr A* up to X-ray energies. In addition, using the inverse Compton scattering picture, we explain the high energy 20-120 keV emission from the direction toward Sgr A*, and the lack of one-to-one X-ray counterparts to near-IR flares, by the variation of the magnetic field and the spectral index distributions of this population of nonthermal particles. In this picture, the evidence for the variability of submillimeter emission during a near-IR flare is produced by the low-energy component of the population of particles emitting synchrotron near-IR emission. Based on the measurements of the duration of flares in near-IR and submillimeter wavelengths, we argue that the cooling could be due to adiabatic expansion with the implication that flare activity may drive an outflow.Comment: 48 pages, 12 figures, ApJ (in press