The pale evidence for treatment of iron-deficiency anaemia in older people

Funding The authors have received funding to carry out a pilot RCT on management of IDA in older people from the Chief Scientist Office, Scotland.Peer reviewedPostprin

Global W2,pW^{2,p} estimates for solutions to the linearized Monge--Amp\`ere equations

In this paper, we establish global $W^{2,p}$ estimates for solutions to the linearized Monge-Amp\`ere equations under natural assumptions on the domain, Monge-Amp\`ere measures and boundary data. Our estimates are affine invariant analogues of the global $W^{2,p}$ estimates of Winter for fully nonlinear, uniformly elliptic equations, and also linearized counterparts of Savin's global $W^{2,p}$ estimates for the Monge-Amp\`ere equations.Comment: v2: presentation improve

A cusp electron gun for millimeter wave gyrodevices

The experimental results of a thermionic cusp electron gun, to drive millimeter and submillimeter wave harmonic gyrodevices, are reported in this paper. Using a "smooth" magnetic field reversal formed by two coils this gun generated an annular-shaped, axis-encircling electron beam with 1.5 A current, and an adjustable velocity ratio alpha of up to 1.56 at a beam voltage of 40 kV. The beam cross-sectional shape and transported beam current were measured by a witness plate technique and Faraday cup, respectively. These measured results were found to be in excellent agreement with the simulated results using the three-dimensional code MAGIC

Integrated electronic prescribing and robotic dispensing: a case study

INTRODUCTION: To quantify the benefits of electronic prescribing directly linked to a robotic dispensing machine. CASE DESCRIPTION: Quantitative case study analysis is used on a single case. Hospital A (1,000 beds) has used an integrated electronic prescribing system for 10 years, and in 2009 linked two robotic dispensing machines to the system. The impact on dispensing error rates (quality) and efficiency (costs) were assessed. EVALUATION AND DISCUSSION: The implementation delivered staff efficiencies above expectation. For the out-patient department, this was 16% more than the business case had suggested. For the in-patients dispensary, four staff were released for re-deployment. Additionally, £500,000 in stockholding efficiency above that suggested by the business case was identified. Overall dispensing error rates were not adversely affected and products dispensed by the electronic prescribing - robot system produced zero dispensing errors. The speed of dispensing increased also, as the electronic prescribing - robot combination permitted almost instantaneous dispensing from the point of a doctor entering a prescription. CONCLUSION: It was significant that the combination of electronic prescribing and a robot eliminated dispensing errors. Any errors that did occur were not as a result of the electronic prescribing - robotic system (i.e. the product was not stocked within the robot). The direct linking of electronic prescribing and robots as a dispensing system together produces efficiencies and improves the quality of the dispensing process

Management of Grassy Balds Communities in the Roan Highlands

The Highlands of Roan Mountain best exemplify that which is rare and unique within high elevation communities of the Southern Appalachian Mountains. The Roan Highlands are protected through a landscape-level conservation initiative originally established by the Southern Appalachian Highlands Conservancy (SAHC) and the U. S. Forest Service (USFS) in 1974. The Roan massif rises more than 6,000 feet above mean sea level and straddles the border of North Carolina and Tennessee in the Pisgah and Cherokee National Forests, respectively. Among its unique aspects, the Roan supports at least 800 known plant species, 27 rare plant communities, and 33 federally or state-listed threatened and endangered species; as of this writing, 35 species obtain a rank of G3, G2, or G1. The Roan’s threatened community types include: Heath Balds, Seeps, Red Spruce-Fraser Fir Forests, Grassy Balds, and Rocky Summits, of which the latter three are deemed in need of restoration, in addition to preservation. The Grassy Balds have been a focus of management in the Roan Highlands, largely due to their iconic status within these high elevation communities. To wit, the Grassy Balds provide splendid, panoramic views of the high elevation landscape; they predate European settlement and their origins are enigmatic; the Roan’s Grassy Balds represent the highest quality and the longest linear stretch of this community type remaining in the Southern Appalachians; they provide habitat for numerous regionally and locally rare species. The Roan’s Grassy Balds currently occupy less than 25 percent of their historic extent. Trees, shrubs, and blackberries have encroached into the Grassy Balds due to a lack of natural and anthropogenic disturbances and inadequate levels of management. With so much biodiversity at stake, the scientific and conservation communities determined that broad management partnerships are necessary to sustain the rare elements of the Roan; multiple governmental and non-governmental organizations have worked together toward mutual conservation goals since the early 1970s. Currently known as the Roan Stewardship Committee, these managing entities collaborated with the U.S. Forest Service to establish a restoration goal of nearly 1,000 acres of the Roan’s Grassy Balds in 1991, but that goal has not been met. In this study, we will present information recently gathered by members of the Roan Stewardship Committee on efforts to maintain and restore Grassy Balds communities in the Roan Highlands, emphasizing recent summaries of historic and current adaptive management efforts, as well as data from the first year (2008) of a browsing study known as the Baa-tany Goat Project

Explaining anomalous responses to treatment in the Intensive Care Unit

The Intensive Care Unit (ICU) provides treatment to critically ill patients. When a patient does not respond as expected to such treatment it can be challenging for clinicians, especially junior clinicians, as they may not have the relevant experience to understand the patient’s anomalous response. Datasets for 10 patients from Glasgow Royal Infirmary’s ICU have been made available to us. We asked several ICU clinicians to review these datasets and to suggest sequences which include anomalous or unusual reactions to treatment. Further, we then asked two ICU clinicians if they agreed with their colleagues’ assessments, and if they did to provide possible explanations for these anomalous sequences. Subsequently we have developed a system which is able to replicate the clinicians’ explanations based on the knowledge contained in its several ontologies; further the system can suggest additional explanations which will be evaluated by the senior consultant

The effect of prolonged simulated non- gravitational environment on mineral balance in the adult male, volume 1 Final report

Effect of prolonged bed rest with simulated weightlessness on mineral balance in male adult - Vol.

Establishment of \u3ci\u3eListeria monocytogenes\u3c/i\u3e in the Gastrointestinal Tract

Listeria monocytogenes is a Gram positive foodborne pathogen that can colonize the gastrointestinal tract of a number of hosts, including humans. These environments contain numerous stressors such as bile, low oxygen and acidic pH, which may impact the level of colonization and persistence of this organism within the GI tract. The ability of L. monocytogenes to establish infections and colonize the gastrointestinal tract is directly related to its ability to overcome these stressors, which is mediated by the efficient expression of several stress response mechanisms during its passage. This review will focus upon how and when this occurs and how this impacts the outcome of foodborne disease

Multilayer microwave windows for wideband gyro-amplifiers

This paper presents the design and measurement of a HE11 mode multilayer window for a W-band gyro-amplifier. The window acts to seal the vacuum inside the amplifier whilst coupling out microwave power with minimal reflection and absorption. The Gaussian-like HE11 mode is used in order to achieve the lowest reflection through the window. Operating over 90-100 GHz the simulated reflection of this window is better than -30 dB. The design, simulation and microwave measurement of the window is presented

Engineering a static verification tool for GPU kernels

We report on practical experiences over the last 2.5 years related to the engineering of GPUVerify, a static verification tool for OpenCL and CUDA GPU kernels, plotting the progress of GPUVerify from a prototype to a fully functional and relatively efficient analysis tool. Our hope is that this experience report will serve the verification community by helping to inform future tooling efforts. © 2014 Springer International Publishing