475 research outputs found

    At Short Telomeres Tel1 Directs Early Replication and Phosphorylates Rif1

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    Funding AS was supported by a Cancer Research UK PhD studentship and ORSAS. SK is supported by a Scottish Universities Life Sciences Alliance PhD studentship. This work was supported by Cancer Research UK grant A13356 to ADD (http://www.cancerresearchuk.org). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

    Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?

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    This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.Peer reviewedPublisher PD

    Genetic analysis of mutations affecting the initiation of yeast sporulation

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    Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation

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    Open Access funded by Medical Research Council Acknowledgments We thank Dr Anja Bielinsky for plasmids and Dr. M.K. Raghuraman for a cdc9-1 strain. Alexander Lorenz (University of Aberdeen) provided valuable comments on the manuscript. This work was supported by Biotechnology and Biological Sciences Research Council (BBSRC) grant BB/K006304/1 to A.D., Medical Research Council Career Development Fellowship MR/L019698/1 to T.K., and MEXT Grant-in-Aid for Scientific Research on Innovative Areas to K.S.Peer reviewedPublisher PD

    Chromosome replication: from ORC to fork

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    A report on the 2001 Eukaryotic DNA Replication meeting, Cold Spring Harbor Laboratory, New York, 5-9 September 2001
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