Genetic parameters for�resistance to the Salmonella abortusovis vaccinal strain Rv6 in sheep

An experimental population (1216 lambs from 30 sires) of the Inra401 sheep was created in an Inra flock to allow QTL detection for susceptibility to Salmonella infection, wool and carcass traits. The Inra401 is a sheep composite line developed from two breeds: Berrichon du Cher and Romanov. At 113 days of age on average, the lambs were inoculated intravenously with 10(8 )Salmonella abortusovis Rv6 (vaccinal strain). They were slaughtered 10 days after the inoculation. Several traits were measured at inoculation and/or slaughtering to estimate the genetic resistance of the lambs to Salmonella infection: specific IgM and IgG1 antibody titres, body weight loss, spleen and pre-scapular node weights and counts of viable Salmonella persisting in these organs. This paper presents a quantitative analysis of the genetic variability of the traits related to salmonellosis susceptibility. The heritabilities of the traits varied between 0.10 and 0.64 (significantly different from zero). Thus, in sheep as well as in other species, the determinism of resistance to Salmonella infection is under genetic control. Moreover, the correlations between the traits are in agreement with the known immune mechanisms. The genetic variability observed should help QTL detection

San-Antonio Ltd. : competition and domination in the field of crime literature and film noir in post 1950s France

THESIS 8093The modernity of the detective novel, associated with its narratological and formal innovations, entails a reversal of the relationship between the text and its author. The situation of the detective fiction writer, with his submission to the laws of genre, to the conditions of exploitation it implies and to his actual relegation in favour of his characters succeeds in a \u27functionalisation\u27 of the author, as seen in Post-Structural criticism. The response to this dissolution of authority results in two distinct strategies among French Post-War detective fiction authors. On the one hand, the writer emphasizes the commercial aspect of his work and his situation as producer within the cultural industry. On the other hand, he instigates a questioning of literary hierarchies and the symbolic discrimination they imply, leading to his affirmation of the inherently literary quality of his production

On high-speed connections and the location of activities

We study the impact of a high-speed connection between two regional economies on the location of production activities, using the simple plant-location problem and toy networks. As expected, the relative value of fixed production costs to transportation costs is crucial in the determination of facility locations. Less expected is the fairly strong instability observed in the structure of the locational pattern of facilities when the relative value of the fixed costs changes. The construction of a piece of infrastructure has an impact on the regional structure of production provided that it allows for a substantial reduction in transport spending. When scale economies in production are large, one regional center swallows up the other and may eventually become the only production center within the integrated economy.