A NOvel radio multiservice adaptive network architecture for 5G networks

Proceeding of: 2015 IEEE 81st Vehicular Technology Conference (VTC Spring)This paper proposes a conceptually novel, adaptive and future-proof 5G mobile network architecture. The proposed architecture enables unprecedented levels of network customisability, ensuring stringent performance, security, cost and energy requirements to be met; as well as providing an API-driven architectural openness, fuelling economic growth through over-the-top innovation. Not following the 'one system fits all services' paradigm of current architectures, the architecture allows for adapting the mechanisms executed for a given service to the specific service requirements, resulting in a novel service- and context-dependent adaptation of network functions paradigm. The technical approach is based on the innovative concept of adaptive (de)composition and allocation of mobile network functions, which flexibly decomposes the mobile network functions and places the resulting functions in the most appropriate location. By doing so, access and core functions no longer (necessarily) reside in different locations, which is exploited to jointly optimize their operation when possible. The adaptability of the architecture is further strengthened by the innovative software-defined mobile network control and mobile multi-tenancy concepts

Performance of HARQ with Reduced Size Retransmissions using Network Coding Principles

Abstract—This paper discusses retransmission approaches to improve the throughput performance of Hybrid-ARQ (HARQ) schemes in a point-to-point single user 3rd Generation Partnership Project (3GPP) Long Term Evolution (LTE) uplink system. One goal of communication systems is to achieve a reliable transmission with a throughput performance as close as possible to channel capacity. For that, reducing the channel utilization will improve the throughput performance. Instead of sending two retransmission packets for two HARQ processes of one users, a previously published HARQ scheme uses the XOR combining of these packets to get only one retransmission packet with the same size. Similar to this idea, a new varied scheme performs XOR combining of parts of one conventional full retransmission to generate a smaller retransmission packet. Both approaches will reduce the channel utilization. They will be compared with a HARQ system in LTE uplink using a full size retransmission and a half size retransmission. The main focus of this work is the throughput performance evaluation of these schemes in an LTE link-level simulator. Index Terms—Network coding, HARQ, In-Packet, LTE uplink. I

Initial treatment of steroid-sensitive idiopathic nephrotic syndrome in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre trial (INTENT study)

Introduction Idiopathic nephrotic syndrome is the most common glomerular disease in childhood with an incidence of 1.8 cases per 100 000 children in Germany. The treatment of the first episode implies two aspects: induction of remission and sustainment of remission. The recent Kidney Disease Improving Global Outcomes, American Academy of Pediatrics and German guidelines for the initial treatment of the first episode of a nephrotic syndrome recommend a 12-week course of prednisone. Despite being effective, this treatment is associated with pronounced glucocorticoid-associated toxicity due to highdose prednisone administration over a prolonged period of time. The aim of the INTENT study (Initial treatment of steroid-sensitive idiopathic nephrotic syndrom in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre trial) is to show that an alternative treatment regimen with mycophenolic acid is not inferior regarding sustainment of remission, but with lower toxicity compared with treatment with glucocorticoids only. Methods and design The study is designed as an open, randomised, controlled, multicentre trial. 340 children with a first episode of steroid-sensitive nephrotic syndrome and who achieved remission by a standard prednisone regimen will be enrolled in the trial and randomised to one of two treatment arms. The standard care group will be treated with prednisone for a total of 12 weeks; in the experimental group the treatment is switched to mycophenolate mofetil, also for a total of 12 weeks in treatment duration. The primary endpoint is the occurrence of a treated relapse within 24 months after completion of initial treatment. Ethics and dissemination Ethics approval for this trial was granted by the ethics committee of the Medical Faculty of the University of Heidelberg (AFmu-554/2014). The study results will be published in accordance with the Consolidated Standards of Reporting Trials statement and the Standard Protocol Items: Recommendations for Interventional Trials guidelines. Our findings will be submitted to major international paediatric nephrology and general paediatric conferences and submitted for publication in a peer-reviewed, open-access journal

Pelolinea submarina gen. nov., sp. nov., an anaerobic, filamentous bacterium of the phylum Chloroflexi isolated from subseafloor sediment offshore Shimokita, Japan

http://www.godac.jamstec.go.jp/darwin/cruise/chikyu/902/

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present