ANALISIS SUMBER DAN PENGGUNAAN MODAL KERJA PADA PT. ARITA PRIMA INDONESIA Tbk TAHUN 2016-2019

This study aims to see the working capital conditions of PT. Arita Prima Indonesia Tbk by calculating the source and use of working capital. The results of calculating the source and use of working capital at PT. Arita Prima Indonesia Tbk for the period 2016-2019, namely the development of working capital has increased by 3.39% in the 2016-2017 period and shows an excess of working capital in 2017 amounting to IDR 2,737,702,490. For the 2017-2018 period, the development of working capital increased by 28.52%, indicating an excess of working capital in 2018 amounting to Rp. 23,316,600,337. Whereas in the 2018-2019 period, the development of working capital decreased by 0.19%, indicating a shortage of working capital in 2019 amounting to Rp.204,079,037. The use of working capital at PT. Arita Prima Indonesia Tbk for the 2016-2019 period, namely the use of working capital in the 2016-2017 period is appropriate because in the operational management of PT. Arita Prima Indonesia Tbk has excess working capital of Rp. 2,737,702,490. The use of working capital in the 2017-2018 period is appropriate because in the operational management of PT. Arita Prima Indonesia Tbk, there is an excess of working capital of Rp. 23,316,600,337. Meanwhile, the use of working capital in the 2018-2019 period is not appropriate because in the operational management of PT. Arita Prima Indonesia Tbk, there is a working capital deficiency of Rp. 204,079,037. Keywords:Working Capital, Sources and Use of Working Capita

Antibacterial Activity of Leaf Extracts of Anredera cordifolia (Ten.) Steenis and Muntingia calabura L. Against Streptococcus pneumoniae

Antibacterial resistance in Streptococcus pneumoniae has been increasing and is one of ongoing global concern.  The need to find new antibacterial agents against Streptococcus pneumoniae is of paramount importance. Medicinal plants are prospective sources of antibacterial agents. The aims of the present study were to determine the activity of leaf extraxt of Anredera cordifolia (Ten.) Steenis and Muntingia calabura L. against Streptococcus pneumoniae.  Leaves of Anredera cordifolia (Ten.) Steenis were extracted using 96% ethanol, while the leaves of Muntingia calabura L were extracted using 100% methanol.  The leaf extracts of the two plants obtained were bioassayed for antibacterial activity against Streptococcus pneumoniae ATCC 49619 and a clinical isolate Streptococcus pneumoniae PU 067.  Results showed that leaf extracts of both Anredera cordifolia (Ten.) Steenis and Muntingia calabura L. have antibacterial activity in vitro against Streptococcus pneumoniae ATCC 49619 at crude extract concentrations of 25%, 50%, 75% and 100% (w/v). Both plants extracts showed strongest activity against S. pneumoniae ATCC 49619 at extract concentration of 75%.   In addition, the extracts of both plants have inhibitory activity against growth of the clinical isolate Streptococcus pneumoniae PU 067. Both plant extracts showed strongest activity against S. pneumoniae PU 067 at extract concentration of 100%.  Therefore, leaf extracts of Anredera cordifolia (Ten.) Steenis and Muntingia calabura L. can potentially be used as a source of antibacterial agent for Streptococcus pneumoniae. Keywords: Antibacterial agent, Anredera cordifolia (Ten.) Steenis, Muntingia calabura L., Streptococcus pneumoniae

Activity of Skin Secretions of Frog Fejervarya limnocharis and Limnonectes macrodon against Streptococcus pneumoniae Multidrug Resistant and Molecular Analysis of Species F. limnocharis

Indonesia has about 450 frog species which is approximately 20% of frog species in the world. Among frog species found in Indonesia are Fejervarya limnocharis dan Limnonectes macrodon belonging to family Dicroglossidae. Frog skin secretion is considered to have a potency to be used as an alternative source of antibacterial agent against Streptococcus pneumoniae multidrug resistant (MDR). The aims of the present study were to analyze antibacterial activity of skin secretions of F. limnocharis and L. macrodon against S. pneumoniae multidrug resistant (MDR) and conduct molecular phylogenetic analysis of the frog used to ensure classification of frog species. The release of skin secretion was stimulated using epinephrine injection. Antibacterial activity of the skin secretions was tested using the well and paper disc methods. Results showed that skin secretions of F. limnocharis have antibacterial activity against S. pneumoniae multidrug resistant (MDR) SPN1307. The activity, however, was lower compared to that of chloramphenicol in both well and paper disc methods. On the other hand, skin secretions of L. macrodon failed to inhibit the growth of S. pneumoniae multidrug resistant (MDR) SPN1307. Molecular phylogenetic analysis was carried out on F. limnocharis based on DNA sequence of a partial fragment of mitochondrial cytochrome oxidase subunit I (COI) gene. Results showed that the frog F. limnocharis is closely related (97%) to Fejervarya sp from Bali. Skin secretions of F. limnocharis, therefore, has the potency to be developed as a source of antibacterial agents against S. pneumoniae multidrug resistant (MDR) SPN1307

Peningkatan Pengetahuan dan Kemampuan Penanggulangan Bencana Banjir melalui Sosialisasi di Guru dan Siswa di Kota Bekasi

According to Law Number 24 of 2007, Flood is an event or condition where an area or land is submerged due to an increased volume of water. The impact of floods often causes human casualties, physical losses, property losses, social, economic losses, environmental damage, infrastructure damage, and psychological impacts. Floods occur in almost all parts of Indonesia, especially during the rainy season in areas with high rainfall intensity. AL-Fajar Islamic College, Jatiasih District, Bekasi City, West Java Province is one of the educational facilities that has and is often affected by floods in the area.The problem of limited information and public knowledge about flood disaster management is a vulnerability factor for the risks and impacts of the flood disaster itself. This requires socialization of flood management for communities affected by flood disasters. The purpose of this activity is to increase the knowledge and ability of the community in dealing with and reducing disaster risk. The results of this activity are believed to provide increased knowledge, ability and preparedness in dealing with threats and minimizing the impact of flood disasters

Detection of Subclinical Mastitis in Dairy Cows using California Mastitis Test and Udder Pathogen

Subclinical mastitis is an infection of the udder devoid of clinical symptoms, bacteria are one of the causes behind this disease. In the present study, we investigated subclinical mastitis in dairy cows using the California mastitis test (CMT) and udder pathogens from KUNAK (Kawasan Usaha Peternak Sapi Perah) Cibungbulang, Bogor, West Java, Indonesia. We randomly collected 102 milk samples from dairy farms in different stalls. We found that 87 out of the 102 (86 %) milk samples were positive for CMT test with level+1, level+2, and level+3 were 22 %, 45 %, and 33 % respectively. We also identified three different major bacterial groups: staphylococcus, streptococcus, and enterobacteria based on gram staining, oxidase test, and coagulase test. It can be concluded that the case of bovine subclinical mastitis in Kunak Bogor was very high and caused by various bacteria which infected cows

Peningkatan Sosialiasi Pelayanan Publik Satu Pintu tentang Perijinan Usaha bagi Pedagang Usaha Mikro Pasar Kaget Pagi Jalan Elang Raya, Pondok Timur Indah, RT.05/RW.04, Kel. Mustikasari, Kec. Mustikajaya, Kota Bekasi

Micro Business or Street Vendors are basically informal sector traders. In general, the Informal Sector are small-scale unofficial business units that produce and distribute goods and services without having a business license and or location permit based on the provisions of the applicable laws and regulations.The purpose of this community service is to provide insight and knowledge about administrative procedures in the process of obtaining business licenses to obtain business legality, both through licensing services at the Mustika Jaya District office, as well as through licensing services at the One-Stop Integrated Investment and Licensing Service Office ( PMPTSP) Bekasi City and also provided outreach regarding the mechanism and terms of loans that can be made by Pasar Pagi traders to pawnshop city of Bekasi in particular.The method used is conventional counseling or socialization activities, which are carried out face-to-face. The results of this community service indicate an increase in participants' insight and understanding of the mechanisms and requirements for business permits and loans at pawnshop city of Bekasi

Peningkatan Literasi Kewirausahaan Siswa SMK Husada Persada Indonesia di Kota Bekasi

The spirit of entrepreneurship needs to be instilled in the younger generation of millennials, so that it inspires the Stiami Institute Lecturers to carry out services in terms of entrepreneurial literacy to Persada Husada Indonesia School Bekasi City Students. This PKM aims; (1) To provide understanding and knowledge to students of SMK Persada Husada Indonesia Bekasi City about Entrepreneurship; (2) To provide stimulus to Persada Husada Indonesia Bekasi City students in an effort to increase their interest in entrepreneurship. Problems faced; (1) Lack of understanding of entrepreneurship; and (2) Still low interest in entrepreneurship To solve these problems comprehensively, assistance from various parties is needed. In this case, the Lecturers of the Stiami Institute of Social and Management Sciences have the responsibility to participate in solving the above problems, among others through community service programs.The methods used in solving the problem are; (1) Lecture; (2) Discussion; (3) Question and Answer; (4) Evaluation. A comparative des of students understanding and knowledge before and after participating in this activity, in general it is known that there was an increase in paticipants’ understanding and knowledge based on the results in table 1.The results achieved in the implementation of this PKM are: 1. Students have knowledge about Entrepreneurship.  2. Students have knowledge related to entrepreneurial characters, 3. Students are motivated to be involved in the world of entrepreneurship

Phylogenetic Analysis of Cytochrome Oxidase I from Buduk Toads Duttaphrynus melanostictus and Phrynoidis asper from Bogor

Indonesia have high diversity of Amphibians. Amphibians have an important role in ecosystem and produce many bioactive peptides. However, the genetic information of amphibians from Indonesia is very limited, especially Duttaphrynus melanostictus and Phrynoidis asper. The aims of this study are to determine the nucleotide sequence of cytochrome oxidase I (COI) from D. melanostictus and P. asper, to analyze their genetic diversity and their phylogenetic relationship. A total 668 base pairs of COI gene fragment were successfully amplified and their nucleotide sequence determined. P. asper (5 haplotypes) samples group have high haplotype diversity compared to D. melanostictus (1 haplotype). The results of Basic Local Alignment Search Tools (BLAST) to the NCBI and BOLD database, showed 99 % - 100 % identity to sequence of D. melanostictus. For the sequence of P. asper showed 99.23 % identity to sequence P. asper in BOLD database. There was no sequence of COI gene of P. asper in NCBI database. Genetic relationship among species in family Bufonidae, indicated that D. melanostictus has closer relation to P. asper than to another species, inspite of their pharapyletic characteristic. For intern species relationship of D. melanostictus, the data showed that D. melanostictus from Bogor have closer relationship to D. melanostictus from India than D. melanostictus from China

Preparation and immunogenicity of gold glyco-nanoparticles as antipneumococcal vaccine model

Nanotechnology-based fully synthetic carbohydrate vaccines are promising alternatives to classic polysaccharide/protein conjugate vaccines. We have prepared gold glyco-nanoparticles (GNP) bearing two synthetic carbohydrate antigens related to serotypes 19F and 14 of Streptococcus pneumoniae and evaluated their immunogenicity in vivo. Results: A tetrasaccharide fragment of serotype 14 (Tetra-14), a trisaccharide fragment of serotype 19F (Tri-19F), a T-helper peptide and d -glucose were loaded onto GNP in different ratios. Mice immunization showed that the concomitant presence of Tri-19F and Tetra-14 on the same nanoparticle critically enhanced the titers of specific IgG antibodies toward type 14 polysaccharide compared with GNP exclusively displaying Tetra-14, while no IgG antibodies against type 19F polysaccharide were elicited. Conclusion: This work is a step forward toward synthetic nanosystems combining carbohydrate antigens and immunogenic peptides as potential carbohydrate-based vaccines