3,859 research outputs found
The evolutionary ecology of interactive synchronism: The illusion of the optimal phenotype
In this article, we discuss some ecological-evolutionary strategies that allow synchronization of organisms, resources, and conditions. Survival and reproduction require synchronization of life cycles of organisms with favourable environmental and ecological features and conditions. This interactive synchronization can occur directly, through pairwise or diffuse co-evolution, or indirectly, for example, as a result of actions of ecosystem engineers and facilitator species. Observations of specific interactions, especially those which have coevolved, may give the false impression that evolution results in optimal genotypes or phenotypes. However, some phenotypes may arise under evolutionary constraints, such as simultaneous evolution of multiple traits, lack of a chain of fit transitional forms leading to an optimal phenotype, or by limits inherent in the process of selection, set by the number of selective deaths and by interference between linked variants. Although there are no optimal phenotypes, optimization models applied to particular species may be useful for a better understanding of the nature of adaptations. The evolution of adaptive strategies results in variable life histories. These strategies can minimize adverse impacts on the fitness of extreme or severe environmental conditions on survival and reproduction, and may include reproductive strategies such as semelparity and iteroparity, or morphological, physiological, or behavioural traits such as diapause, seasonal polyphenism, migration, or bet-hedging. However, natural selection cannot indefinitely maintain intra-population variation, and lack of variation can ultimately extinguish populations
The competitiveness of the Portuguese wine sector and a case study of exports and activity diversification in the Vinhos Verdes region
The world wine market is currently characterised by two principal wine suppliers: the European and the New World. Countries such as France, Italy, Spain and Portugal have witnessed a tremendous growth in the New World wine- makers (Australia, Chile, South Africa, etc.). As competition continues to intensify, wineries are searching for new channels to increase revenues and many vintners chose to develop other activities. Portugal is one of the European countries that present several natural and technical constraints which might be now resulting in modest performance regarding its position in the global wine market, competitiveness and dynamism required to overcome difficulties. The main objective of the study is to provide information to vintners concerning the current situation of the wine industry and possibly to present "holes" in the market which overall might be explored as new business opportunities. To that end, the research will attempt to measure the competitiveness of the Portuguese wine industry and its behaviour during a time period considered. This will be based on indices such as the trade intensity index, revealed comparative advantage, auto- sufficiency and market share ratios. This paper will also try to analyse empirically the specific case of exports and activity diversification in the Vinhos Verdes region.wine industry, competitiveness indices, exports, activity diversification, Vinhos Verdes wine, Agribusiness,
Induced mass in N=2 super Yang-Mills theories
The masses of the matter fields of N=2 Super-Yang-Mills theories can be
defined as parameters of deformed supersymmetry transformations. The
formulation used involves central charges for the matter fields. The explicit
form of the deformed supersymmetry transformations and of the invariant
Lagrangian in presence of the gauge supermultiplet are constructed. This works
generalizes a former one, due to the same authors, which presented the free
matter case.Comment: 15 pages, Late
Validação de sequências promotoras de expressão genética de caráter tecido-expecifico no genoma de Banana (Musa spp.).
The anticancer properties of dietary polyphenols and its relation with apoptosis
Aberrantly regulated apoptosis is involved in the pathogenesis of several diseases and defective apoptosis leads to uncontrolled cell proliferation and tumorigenesis. Cancer is an example of a pathologic condition where the normal mechanisms of cell cycle regulation are dysfunctional either by excessive cell proliferation, inhibited/suppressed apoptosis or both. Dietary habits are estimated to contribute to, at least, one third of all human cancers, showing that dietary components can exacerbate or interfere with carcinogenesis. However, several epidemiological studies have revealed that some dietary factors can decrease the risk of different types of cancer. Apoptosis is suggested to be a crucial mechanism for the chemopreventive properties associated with several dietary factors by eliminating potentially deleterious (damaged/mutated) cells. Food, a readily available item, contains several promising chemopreventive agents. Polyphenols are serious candidates since they are responsible for the cancer protective properties of a diet rich in vegetables and fruits: numerous phenolic compounds showed antiproliferative and cytotoxic effects, and more specifically pro-apoptotic activities, in several cancer cells lines and animal tumor models. The aim of the present review is to analyze and summarize several aspects related to the molecular mechanisms of apoptosis induced by dietary factors with particular emphasis on polyphenols. Dietary factors that can activate cell death signals and induce apoptosis, preferentially in precancerous or malignant cells, and the study of their apoptotic inducing targets can represent a mean to devise new strategies for cancer prevention in the future
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