Emerging role of inventory management at a liquor store in New Zealand

Inventory management has different applications as per the business model. However, it all boils down to reconciliation of stock, forecasting demand trends and accordingly placing orders so that you never run out of stock. In this research, discussion will be based on a small business model, ‘Thirsty Liquor’, a retail liquor store located in Hamilton, New Zealand. Liquor businesses always face competitive competition as the demand is constant and liquor is available in supermarkets and in a variety of liquor stores. This research focuses on the emerging role of inventory management and the problems faced by the business in implementing this system. For this research, qualitative methods were used and interviews were conducted to gain first-hand information. Personal observations were made. Interviews were conducted with managers of other stores as well. The outcome of this research highlighted the problem of storage place or a separate warehouse to maintain stock. Poor co-ordination amongst the staff resulted in few suggestions being made based of the gathered input. However, further research on liquor stores all over New Zealand would give an ideal understanding of the inventory management systems used by other retailers

ANTIDEPRESSANT-LIKE ACTIVITY OF FLOWERS OF TECOMELLA UNDULATA IN MICE SUBJECTED TO CHRONIC UNPREDICTABLE MILD STRESS

Objective: Flowers of Tecomella undulata have been reported to be a rich source of flavonoids such as rutin and quercetin. The present study was designed to evaluate the effect of ethanol extract of flowers of T. undulata on chronic unpredictable mild stress (CUMS)-induced depression in Swiss young male albino mice.Methods: The mice were subjected to CUMS for 21 successive days. Ethanol extract of the flowers (50, 100, and 200 mg/kg, p.o.) and fluoxetine (20 mg/kg, p.o.) per se was administered for 21 successive days to separate groups of unstressed and stressed mice. Tail suspension test (TST) and sucrose preference test were used to evaluate the effect of the extract on depression-like behavior in mice.Results: Extract of flowers of T. undulata (100 and 200 mg/kg) significantly decreased immobility period of stressed mice in TST, indicating significant antidepressant-like activity of the extract. Stress-induced reduced sucrose preference was significantly restored by the extract. There was no significant effect on locomotor activity of mice by the extract and fluoxetine. The extract significantly reversed stress-induced increase in brain malondialdehyde levels; plasma nitrite and corticosterone levels; and also significantly reversed the stress-induced decrease in reduced glutathione and catalase levels. There was no significant effect of the extract on brain MAO-A activity in both unstressed and stressed mice.Conclusion: These results indicated that ethanol extract of flowers of T. undulata showed significant antidepressant-like activity in mice subjected to CUMS, probably through alleviation of oxidative stress and decrease in plasma corticosterone levels

BIONIC CONTACT LENS

Have you ever wished that you could see the world around in front of your eyes as seen by protagonist in science fiction movies like Terminator and Robocop? This is now possible using Bionic contact lens

CYTOMORPHOMETRIC ANALYSIS OF BUCCAL CELLS IN BUILDING WORKERS EXPOSED TO POLYCYCLIC AROMATIC HYDROCARBON IN AND AROUND COIMBATORE DISTRICT

Objective: Building workers are exposed to a mixture of chemicals and polycyclic aromatic hydrocarbons at the time exposure by inhalation which is suspected to cause genetic damage. The aim of the study was to assess the level of genetic damage in south Indian building workers are exposed to PAHs.Methods: 30 Building workers and standardized control groups are examined for frequencies of micronuclei in buccal epithelial cells.Results: The genetic damage observed in the buccal cells of building workers was significantly higher than in controls. Chewing also related to genetic damage since the observed in PAHs exposed groups with chewers was significantly higher than non-chewing workers.Conclusion: Occupational exposure of PAHs from building workplaces has been associated with increased genetic damage and chewers represent an additional risk factor. Exposure to PAHs may be related to increased risk of cancer in building workers

Knowledge Awareness And Practice Regarding Bell's Palsy Among Dental Students In Chennai

Introduction:Bell’s palsy is an idiopathic, acute peripheral palsy of the facial nerve that results in muscle weakness on one side of the face, characterized by sudden onset, and unilateral facial paralysis, lower motor neuron weakness of the facial nerve with no other neurological abnormalities and no readily identifiable cause. The aim of this study was to measure the knowledge and attitude among dental students A self administered questionnaire consisting of 17 questions regarding knowledge and awareness of bell's palsy .Data was collected through google forms. responses were analysed and statistical data is represented as pie charts. From the results 69% of the people selected facial nerve is affected by bell's palsy and 75% of the people selected that bell's palsy affects only one side of the face and 25% disagreed with it. 60% of the study participants said that recovery duration of immediate type facial paralysis is 4 hours. The knowledge of anatomy, diagnosis and treatment was satisfactory and suggest that they have sufficient awareness. Dental students and dentists should be exposed to any medical condition that could happen because of iatrogenic reasons

DEVELOPMENT AND VALIDATION OF SPECTROSCOPIC METHOD FOR SIMULTANEOUS ESTIMATION OF SALBUTAMOL SULPHATE, AMBROXOL HYDROCHLORIDE AND CETIRIZINE HYDROCHLORIDE IN COMBINED PHARMACEUTICAL TABLET FORMULATION: A NOVEL TECHNIQUE FOR IN-VITRO DISSOLUTION STUDIES

Objective: To develop a simple, rapid, accurate, precise and economical spectroscopic method for the simultaneous determination of Salbutamol Sulphate, Ambroxol Hydrochloride and Cetirizine Hydrochloride in combined pharmaceutical tablet formulation and validate as per ICH guidelines. Methods: In this method, the 6.8 pH phosphate buffer was selected for the developing spectral characteristics of the three drugs. The overlay spectra of Salbutamol Sulphate, Ambroxol hydrochloride and Cetirizine hydrochloride were resolved by making the use of simultaneous equation method based on measurement of absorbance at three wavelengths. Results: The λmax of Salbutamol Sulphate, Ambroxol Hydrochloride and Cetirizine hydrochloride were found to be 276 nm, 244 nm and 230 nm. The method obeyed Beer Lambert's law in the concentration range of 10-100 µg/ml for SAL, 2- 18 µg/ml for AMB HCl and 2-20 µg/ml for CET HCl. The high values of correlation coefficient (R) indicated good linearity of calibration plot for the drugs. Result of percentage recovery study confirms the accuracy of proposed method. Percentage RSD for precision and accuracy of the method was found to be less than 2%. LOD values for SAL, AMB, and CET were found to be 0.523 ðœ‡g/mL, 0.450 ðœ‡g/mL and 0.457 ðœ‡g/mL, respectively. LOQ values for SAL, AMB, and CET were found to be 1.372 ðœ‡g/mL, 1.424 ðœ‡g/mL and 1.386 ðœ‡g/mL, respectively. Conclusion: A rapid, economical, accurate, precise and reproducible simultaneous equation spectroscopic method was developed and validated. The proposed method can be employed for routine analysis of Salbutamol Sulphate, Ambroxol Hydrochloride and Cetirizine Hydrochloride in combined pharmaceutical tablet formulation

Histopathological analysis of soft tissue changes in gingival biopsied specimen from patients with underlying corona virus disease associated mucormycosis (CAM)

Corona Virus Disease-2019 (COVID-19) is perhaps the disastrous medical emergencies that has ever hit globally with multiple strains. Amongst various sequelae, mucormycosis may be considered as the most debilitating one. Post COVID-19 mucormycosis is formally regarded as corona virus disease associated mucormycosis (CAM). The aim of the current paper is to present twelve cases of CAM with unique clinical presentation with a detailed histopathological correlation of the gingival biopsied material. Twelve cases of CAM were included in the study who presented initially with non-purulent swelling of the gingiva. The clinic-demographic data pertaining to age, gender, location, laterality and presence of co-morbidities was collected along with histopathological examination of biopsied specimen. The patients ranged from 31-65 years (mean age 47.33 years). There was a male predominance. Clearly, maxillary right gingiva was mostly affected and all cases presented with non purulent, non tender swelling of the gingiva. The incisional biopsy from the gingiva consistently showed pseudoepitheliomatous hyperplasia of the surface epithelium along with vacuolar degeneration, extensive stromal edema, massive mixed inflammatory reaction, congested blood vessels, hemorrhage and abundant multinucleated giant cells. Potassium hydroxide (10% KOH) mount served no additional diagnostic advantage. After two initial biopsies any suspected case of CAM with these features was treated with appropriate antifungal therapy and conservative excision. Gingival swelling with aforementioned histopathological features resembling post COVID-19 histological alterations could be alarming early signs of CAM and are candidate of prompt antifungal therapy rather than repeat biopsy for confirmation

A prospective study of surgical management of dual plating of bicondylar tibial plateau fracture

Background: Tibial condyles with their articular surface forms major part of the knee joint, plays an important role in weight transmission and mobility. The proximal tibia fractures account for 1% of all the fractures. If these high velocity intra/peri articular fractures are not treated properly there will be high degree incidences of malunion, non-union, peri-op infections vs collapse of the medial condyle, ligamentous instability, malalignment of the axis, articular incongruity leading to post traumatic arthritis. Aim was to assess the anatomical reduction of articular surface of upper end of tibia and knee joint perfectly by operative treatment with internal fixation.  Methods: The study was done for a period of 1 years on 30 patients with bicondylar tibial plateau fractures diagnosed with Schatzker type V and VI. Age ranged from 20-60 years with majority being in 30-39 years range with a largely male preponderance. Patients were followed up to 12 months.Results: Our study reported Honkonen Jarvinen clinical outcome to be 86% excellent, 11.7% good and 1.7% fair. The functional outcome was 81% excellent, 13% good, 5% fair and 1% poor. The Radiological outcome showed 79.2% excellent, 12% good, 0.70% fair results. Our study used Honkonen Jarvinen criteria for radiological, functional, clinical outcome which showed excellent to good result.  Conclusions: Dual plating is ideal for all bicondylar Tibial plateau fracture of Schatzker type V and VI with appropriate timing of surgery and understanding the anatomy, LCP system, appropriate technique with dual incision, the complication can be minimized, giving excellent to good results.

Conversion of Malic Acid in to Lactic Acid in Aloevera by using Lactic Acid Bacteria

Malic acid is an excellent indicator of gel freshness. This acid is produced naturally in the leaves of aloes and other succulents whose cells contain large, water-filled vacuoles. Under poor handling conditions in the presence of bacteria, malic acid can be broken down to form lactic acid. Gram-negative rod bacteria, which grow in some aloe gels, assimilate malic acid and free glucose and produce other organic acids such as lactate or lactic acid. Lactic acid is one of the major products of carbohydrate break-down by lactic acid bacteria during malolactic fermentation (MLF). Malolactic enzyme demonstrated to be present in most lactic acid bacteria but not in other bacteria, catalyzes the reaction: 1 malate + H+-1lactate+Co2.Avinash Tungala et al. Conversion of Malic Acid in to Lactic Acid in Aloevera by using Lactic Acid Bacteria. J Phytol 3/3 (2011) 01-11

Design optimization of deflection caused after release of multilayer structural membrane of Symmetric Toggle Switch

This paper presents the optimization in deflection caused by the inbuilt stress generated in mechanical or movable membrane of Symmetric Toggle RF MEMS Switch (STS). The movable membrane of STS was initially fabricated with two different materials, i.e. Chrome and Gold. The simulated deflection at 70°C was 11.9 μm, and experimental deflection was 11-12 μm. We present a study of inbuilt deflection reduction in multimetal movable layers without change in actuation voltage of the switch. The design study was initially carried out on cantilevers and then on structural membrane of STS. STS with proposed multilayer of Cr-Au-Au-Ti-Au has a simulated deflection of 0.56 μm at 70°C. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2212