5,743 research outputs found
Single joint perturbation during gait: neuronal control of movement trajectory
The aim of this study was to investigate the effect of single joint displacement on the pattern of leg muscle electromyographic (EMG) activity during locomotion. For the first time, unilateral rotational hip or knee joint displacements were applied by a driven orthotic device at three phases of swing during locomotion on a treadmill. The response pattern of bilateral leg muscle activation with respect to the timing and selection of muscles was almost identical for displacements of upper (hip joint) or lower (knee joint) leg. The leg muscle EMG responses were much stronger when the displacement was directed against the physiological movement trajectory, compared with when the displacement was reinforcing, especially during mid swing. It is suggested that these response patterns are designed to restore physiological movement trajectory rather than to correct a single joint position. Displacements released at initial or terminal swing, assisting or resisting the physiological movement trajectory, were followed by similar and rather unspecific response patterns. This was interpreted as being directed to stabilise body equilibriu
Vertical perturbations of human gait: organisation and adaptation of leg muscle responses
During the last several years, evidence has arisen that the neuronal control of human locomotion depends on feedback from load receptors. The aim of the present study was to determine the effects and the course of sudden and unexpected changes in body load (vertical perturbations) on leg muscle activity patterns during walking on a treadmill. Twenty-two healthy subjects walking with 25% body weight support (BWS) were repetitively and randomly loaded to 5% or unloaded to 45% BWS during left mid-stance. At the new level of BWS, the subjects performed 3-11 steps before returning to 25% BWS (base level). EMG activity of upper and lower leg muscles was recorded from both sides. The bilateral leg muscle activity pattern changed following perturbations in the lower leg muscles and the net effect of the vertical perturbations showed onset latencies with a range of 90-105ms. Body loading enhanced while unloading diminished the magnitude of ipsilateral extensor EMG amplitude, compared to walking at base level. Contralateral leg flexor burst activity was shortened following loading and prolonged following unloading perturbation while flexor EMG amplitude was unchanged. A general decrease in EMG amplitudes occurred during the course of the experiment. This is assumed to be due to adaptation. Only the muscles directly activated by the perturbations did not significantly change EMG amplitude. This is assumed to be due to the required compensation of the perturbations by polysynaptic spinal reflexes released following the perturbations. The findings underline the importance of load receptor input for the control of locomotio
Computerized visual feedback: an adjunct to robotic-assisted gait training
BACKGROUND AND PURPOSE: Robotic devices for walking rehabilitation allow new possibilities for providing performance-related information to patients during gait training. Based on motor learning principles, augmented feedback during robotic-assisted gait training might improve the rehabilitation process used to regain walking function. This report presents a method to provide visual feedback implemented in a driven gait orthosis (DGO). The purpose of the study was to compare the immediate effect on motor output in subjects during robotic-assisted gait training when they used computerized visual feedback and when they followed verbal instructions of a physical therapist. SUBJECTS: Twelve people with neurological gait disorders due to incomplete spinal cord injury participated. METHODS: Subjects were instructed to walk within the DGO in 2 different conditions. They were asked to increase their motor output by following the instructions of a therapist and by observing visual feedback. In addition, the subjects' opinions about using visual feedback were investigated by a questionnaire. RESULTS: Computerized visual feedback and verbal instructions by the therapist were observed to result in a similar change in motor output in subjects when walking within the DGO. Subjects reported that they were more motivated and concentrated on their movements when using computerized visual feedback compared with when no form of feedback was provided. DISCUSSION AND CONCLUSION: Computerized visual feedback is a valuable adjunct to robotic-assisted gait training. It represents a relevant tool to increase patients' motor output, involvement, and motivation during gait training, similar to verbal instructions by a therapist
Modulation of locomotor activity in complete spinal cord injury
The aim of this study was to evaluate the modulation of muscle activity during locomotor-like movements by different walking speeds in subjects with a motor complete spinal cord injury (SCI) compared to actively- and passively-walking control subjects without neurological deficit. Stepping movements on a treadmill were induced and assisted by a driven gait orthosis. Electromyographic (EMG) muscle activity of one leg (rectus and biceps femoris, tibialis anterior and gastrocnemius) was recorded and analyzed at three stepping velocities with similar body weight support in both subject groups. In SCI subjects, the EMG amplitude of biceps femoris, tibialis anterior and gastrocnemius was in general similar or weaker than in passively- and actively-stepping control subjects, but that of rectus femoris was larger. The degree of co-activation between tibialis anterior and gastrocnemius was higher in SCI than in control subjects. A significant velocity-dependent EMG modulation was present in all four-leg muscles in both subject groups. In SCI subjects, this EMG modulation was similar to that in actively stepping control subjects. It is concluded that in complete spastic SCI subjects, spinal neuronal circuits underlying locomotion can to a large extent adequately respond to a change in external drive to adapt the neuronal pattern to a new locomotion speed. The application of various speeds might enhance the effect of locomotor training in incomplete SCI subject
Influence of vestibular and visual stimulation on split-belt walking
We investigated the influence of vestibular (caloric ear irrigation) and visual (optokinetic) stimulation on slow and fast split-belt walking. The velocity of one belt was fixed (1.5 or 5.0-6.0km/h) and subjects (N=8 for vestibular and N=6 for visual experiments) were asked to adjust the velocity of the other belt to a level at which they perceived the velocity of both the belts as equal. Throughout all experiments, subjects bimanually held on to the space-fixed handles along the treadmill, which provided haptic information on body orientation. While the optokinetic stimulus (displayed on face-mounted virtual reality goggles) had no effect on belt velocity adjustments compared to control trials, cold-water ear irrigation during slow (but not fast) walking effectively influenced belt velocity adjustments in seven of eight subjects. Only two of these subjects decreased the velocity of the ipsilateral belt, consistent with the ipsilateral turning toward the irrigated ear in the Fukuda stepping test. The other five subjects, however, increased the velocity of the ipsilateral belt. A straight-ahead sense mechanism can explain both decreased and increased velocity adjustments. Subjects decrease or increase ipsilateral belt velocity depending on whether the vestibular stimulus is interpreted as an indicator of the straight-ahead direction (decreased velocity) or as an error signal relative to the straight-ahead direction provided by the haptic input from the space-fixed handles along the treadmill (increased velocity). The missing effect during fast walking corroborates the findings by others that the influence of vestibular tone asymmetry on locomotion decreases at higher gait velocitie
Quasiclassical Random Matrix Theory
We directly combine ideas of the quasiclassical approximation with random
matrix theory and apply them to the study of the spectrum, in particular to the
two-level correlator. Bogomolny's transfer operator T, quasiclassically an NxN
unitary matrix, is considered to be a random matrix. Rather than rejecting all
knowledge of the system, except for its symmetry, [as with Dyson's circular
unitary ensemble], we choose an ensemble which incorporates the knowledge of
the shortest periodic orbits, the prime quasiclassical information bearing on
the spectrum. The results largely agree with expectations but contain novel
features differing from other recent theories.Comment: 4 pages, RevTex, submitted to Phys. Rev. Lett., permanent e-mail
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Schwarzschild black hole levitating in the hyperextreme Kerr field
The equilibrium configurations between a Schwarzschild black hole and a
hyperextreme Kerr object are shown to be described by a three-parameter
subfamily of the extended double-Kerr solution. For this subfamily, its Ernst
potential and corresponding metric functions, we provide a physical
representation which employs as arbitrary parameters the individual Komar
masses and relative coordinate distance between the sources. The calculation of
horizon's local angular velocity induced in the Schwarzschild black hole by the
Kerr constituent yields a simple expression inversely proportional to the
square of the distance parameter.Comment: 6 pages, 1 figure; improved versio
Mutations in MYOZ1 as well as MYOZ2 encoding the calsarcins are not associated with idiopathic and familial dilated cardiomyopathy
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