45 research outputs found

    Antiferromagnetic spin ladders effectively coupled by one-dimensional electron liquids

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    We study a model of the stripe state in strongly correlated systems consisting of an array of antiferromagnetic spin ladders, each with nlegn_{leg} legs, coupled to each other through the spin-exchange interaction to charged stripes in between each pair of ladders. The charged stripes are assumed to be Luttinger liquids in a spin-gap regime (Luther-Emery). An effective interaction for a pair of neighboring ladders is calculated by integrating out the gapped spin degree of freedom in the charged stripe. The low energy effective theory of each ladder is the usual nonlinear σ\sigma-model with additional cross couplings of neighboring ladders. These interactions are found to favor either in-phase or anti-phase short range spin orderings depending on whether the charge stripe is site-centered or bond-centered as well as on its filling factor and other physical parameters of the charged stripe.Comment: 4 pages with 1 figure, revised introduction and discussion section

    Understanding Skilled Migrants’ Qualification-Matched Employment in the Host Country: A Multidisciplinary Review and a Conceptual Model

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    Globalization has led to an increase in international mobility in many occupational fields. Therefore, scholars from a variety of disciplines have studied the topic of skilled migration. The purpose of this study is to review and synthesize the empirical research on skilled migrants’ qualification-matched employment across multiple disciplines. Skilled migrants are people on the move who possess university degrees or extensive work experience in professional fields when they leave their countries of origin to seek employment elsewhere. This review synthesizes findings of 106 empirical studies published from 1990 to mid-2017 on skilled migrants’ employment. We develop a conceptual model that includes antecedent conditions associated with skilled migrant qualification-matched employment in their host country and its outcomes. We also highlight the role of multi-level factors and moderating variables associated with skilled migrants’ possibility of obtaining qualification-matched employment. Our review has implications for human resource scholars and practitioners concerned with skilled migrants’ employment and labor market

    Durvalumab as monotherapy and in combination therapy in patients with lymphoma or chronic lymphocytic leukemia: The FUSION NHL 001 trial.

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    BACKGROUND: Studies suggest that immune checkpoint inhibitors may represent a promising strategy for boosting immune responses and improving the antitumor activity of standard therapies in patients with relapsed/refractory hematologic malignancies. AIMS: Phase 1/2 FUSION NHL 001 was designed to determine the safety and efficacy of durvalumab, an anti-programmed death ligand 1 (PD-L1) antibody, combined with standard-of-care therapies for lymphoma or chronic lymphocytic leukemia (CLL). METHODS AND RESULTS: The primary endpoints were to determine the recommended phase 2 dose of the drugs used in combination with durvalumab (durvalumab was administered at the previously recommended dose of 1500 mg every 4 weeks) and to assess safety and tolerability. Patients were enrolled into one of four arms: durvalumab monotherapy (Arm D) or durvalumab in combination with lenalidomide ± rituximab (Arm A), ibrutinib (Arm B), or rituximab ± bendamustine (Arm C). A total of 106 patients with relapsed/refractory lymphoma were enrolled. All but two patients experienced at least one treatment-emergent adverse event (TEAE); those not experiencing a TEAE were in Arm C (diffuse large B-cell lymphoma [DLBCL]) and Arm D (DLBCL during the durvalumab monotherapy treatment period). No new safety signals were identified, and TEAEs were consistent with the respective safety profiles for each study treatment. Across the study, patients with follicular lymphoma (FL; n = 23) had an overall response rate (ORR) of 59%; ORR among DLBCL patients (n = 37) was 18%. Exploratory biomarker analysis showed that response to durvalumab monotherapy or combination therapy was associated with higher interferon-γ signature scores in patients with FL (p = .02). CONCLUSION: Durvalumab as monotherapy or in combination is tolerable but requires close monitoring. The high rate of TEAEs during this study may reflect on the difficulty in combining durvalumab with full doses of other agents. Durvalumab alone or in combination appeared to add limited benefit to therapy

    The EMS effect on the italian labour market

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    Universit\ue0 Cattolica del Sacro Cuore, Laboratorio di Analisi Monetari

    High Performance Work Systems, Industrial Relations and Pay Settings in Europe

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    The present study uses data for workplaces in all sectors of ten European countries to investigate whether firms that have introduced new forms of work organization are more likely to use variable pay schemes. Also the role played in by institutional forces and employees\u2019 representatives is investigated. New regimes of work organization are characterised by both new work practices \u2013 such as teams, job rotation, multitasking and flat hierarchies - and higher levels of employees\u2019 direct participation. We find that, in general, schemes of variable pay are more likely to be introduced where new work practices are in place. The presence of employees representatives increases the probability of variable pay, but only when they cooperate with the management in decision-making

    Globalizzazione, specializzazione produttiva e mercato del lavoro italiano

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    Nel lavoro si analizzano gli effetti dell’integrazione internazionale sul mercato del lavoro, distinguendo i diversi canali che legano globalizzazione, specializzazione produttiva, salari e struttura occupazionale. L’attenzione è rivolta al caso dell’Italia, un paese caratterizzato da una sostanziale staticità nel modello di specializzazione, che sembra aver reagito diversamente da altri paesi industriali alla sfida della globalizzazione. Si mostra che in Italia gran parte dell’aggiustamento ha avuto luogo all’interno dei settori, con una riorganizzazione nei processi produttivi e riflessi sulla domanda di lavoro
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