1,600 research outputs found
Blockwise SVD with error in the operator and application to blind deconvolution
We consider linear inverse problems in a nonparametric statistical framework.
Both the signal and the operator are unknown and subject to error measurements.
We establish minimax rates of convergence under squared error loss when the
operator admits a blockwise singular value decomposition (blockwise SVD) and
the smoothness of the signal is measured in a Sobolev sense. We construct a
nonlinear procedure adapting simultaneously to the unknown smoothness of both
the signal and the operator and achieving the optimal rate of convergence to
within logarithmic terms. When the noise level in the operator is dominant, by
taking full advantage of the blockwise SVD property, we demonstrate that the
block SVD procedure overperforms classical methods based on Galerkin projection
or nonlinear wavelet thresholding. We subsequently apply our abstract framework
to the specific case of blind deconvolution on the torus and on the sphere
Estimating the number of change-points in a two-dimensional segmentation model without penalization
In computational biology, numerous recent studies have been dedicated to the
analysis of the chromatin structure within the cell by two-dimensional
segmentation methods. Motivated by this application, we consider the problem of
retrieving the diagonal blocks in a matrix of observations. The theoretical
properties of the least-squares estimators of both the boundaries and the
number of blocks proposed by L\'evy-Leduc et al. [2014] are investigated. More
precisely, the contribution of the paper is to establish the consistency of
these estimators. A surprising consequence of our results is that, contrary to
the onedimensional case, a penalty is not needed for retrieving the true number
of diagonal blocks. Finally, the results are illustrated on synthetic data.Comment: 30 pages, 8 figure
Shot noise in carbon nanotube based Fabry-Perot interferometers
We report on shot noise measurements in carbon nanotube based Fabry-Perot
electronic interferometers. As a consequence of quantum interferences, the
noise power spectral density oscillates as a function of the voltage applied to
the gate electrode. The quantum shot noise theory accounts for the data
quantitatively. It allows to confirm the existence of two nearly degenerate
orbitals. At resonance, the transmission of the nanotube approaches unity, and
the nanotube becomes noiseless, as observed in quantum point contacts. In this
weak backscattering regime, the dependence of the noise on the backscattering
current is found weaker than expected, pointing either to electron-electron
interactions or to weak decoherence
Conserved spin and orbital phase along carbon nanotubes connected with multiple ferromagnetic contacts
We report on spin dependent transport measurements in carbon nanotubes based
multi-terminal circuits. We observe a gate-controlled spin signal in non-local
voltages and an anomalous conductance spin signal, which reveal that both the
spin and the orbital phase can be conserved along carbon nanotubes with
multiple ferromagnetic contacts. This paves the way for spintronics devices
exploiting both these quantum mechanical degrees of freedom on the same
footing.Comment: 8 pages - minor differences with published versio
Cross-linguistic study of vocal pathology: perceptual features of spasmodic dysphonia in French-speaking subjects
Clinical characterisation of Spasmodic Dysphonia of the adductor type (SD) in French speakers by Klap and colleagues (1993) appears to differ from that of SD in English. This perceptual analysis aims to describe the phonetic features of French SD. A video of 6 French speakers with SD supplied by Klap and colleagues was analysed for frequency of phonatory breaks, pitch breaks, harshness, creak, breathiness and falsetto voice, rate of production, and quantity of speech output. In contrast to English SD, the French speaking SD patients demonstrated no evidence pitch breaks, but phonatory breaks, harshness and breathiness were prominent features. This verifies the French authors’ (1993) clinical description. These findings suggest that phonetic properties of a specific language may affect the manifestation of pathology in neurogenic voice disorders
INI1 mutations in meningiomas at a potential hotspot in exon 9
Rhabdoid tumours have been shown to carry somatic mutations in the INI1 (SMARCB1/hSNF5) gene. A considerable fraction of these tumours exhibit allelic losses on chromosome 22. Allelic loss on 22q also is characteristic for meningiomas, however most of these alterations are considered to be associated with mutations of the NF2 gene. We examined a series of 126 meningiomas for alterations in the INI1 gene. Four identical somatic mutations in exon 9 were detected resulting in an exchange of Arg to His in position 377 of INI1. Our observations were reproduced both by using DNA from a new round of extraction and by employing overlapping primers. This mutational hotspot therefore appears to be an important target in the formation of a fraction of meningiomas. In addition, 4 novel polymorphisms of INI1 were characterized. Our data indicate that the INI1 is a second tumour suppressor gene on chromosome 22 that may be important for the genesis of meningiomas. © 2001 Cancer Research Campaign http://www.bjcancer.co
The Iliad’s big swoon: a case of innovation within the epic tradition
In book 5 of the Iliad Sarpedon suffers so greatly from a wound that his ‘‘ψυχή leaves him’. Rather than dying, however, Sarpedon lives to fight another day. This paper investigates the phrase τὸν δὲ λίπε ψυχή in extant archaic Greek poetry to gain a sense of its traditional referentiality and better assess the meaning of Sarpedon’s swoon. Finding that all other instances of the ψυχή leaving the body signify death, it suggests that the Iliad exploits a traditional unit of utterance to flag up the importance of Sarpedon to this version of the Troy story
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