157 research outputs found
Mastering Tai Chi: San Shou - Partner Form
Michael Gilman. Townsend, WA: Gilman Studio, 2005. 240 minutos. DVD
Taiji estilo Xiong en Taiwán: desarrollo histórico & exposición fotográfica protagonizada por el maestro Lin Jianhong
Este artículo presenta una rama del taijiquan de la familia Yang poco conocida fuera de Taiwán. Se denomina estilo Xiong, debido a Xiong Yanghe (1888~1981). Sin embargo, lo poco que se ha publicado en inglés sobre el maestro Xiong es confuso y a veces contradictorio. Utilizando fuentes publica- das en chino (incluyendo los propios escritos de Xiong), documentos inéditos de sus discípulos más destacados, sitios web taiwaneses relativos a la temática, observaciones personales y documentos fotográficos, la información que aquí se ha recopilado debería proporcionar una visión completa del taiji estilo Xiong. Las fuentes en lengua inglesa se han utilizado para dibujar el marco socio-político que influyó de manera profunda en los inicios del desarrollo del taiji de la familia Yang. Las principales conclusiones afectan al linaje de Xiong, su conservación del arte y su significado para el entendimiento de todas las ramas del taijiquan como arte marcial y ejercicio enfocado hacia la salud
Mastering Tai Chi: San Shou - Partner Form
Michael Gilman. Townsend, WA: Gilman Studio, 2005. 240 minutos. DVD
Tai Chi Fighting Set: Two-Person Matching Set
[ES] Muchos no conocen la rutina de dos personas del estilo Yang de Taijiquan, la cual alcanza, en este arte, los mayores niveles de efectividad en el combate. No es frecuente en observarla en las gentes de la República de China o de Taiwán, y prácticamente no existe fuera de estos dos países. Sólo tengo con-ciencia de unos pocos profesores en los Estados Unidos y en otros lugares que enseñan este ejercicio avanzado por parejas, y ha sido una sorpresa que YMAA lo haya editado en formato de vídeo
Tai Chi Fighting Set: Two-Person Matching Set
Yang Jwing-Ming. Roslindale, MA: YMAA Publication Center, 2004. 120 minutos. Vídeo casete
Mastering Tai Chi: San Shou - Partner Form
[ES] Buscando materiales de referencia relativos a la rutina de dos personas denominada San Shou (a veces traducida como “Manos que Dispersan”), propia del estilo Yang del Taijiquan, es evidente que existen pocos en forma de artículos, libros, vídeos o DVDs. En relación con el vídeo del Dr. YangJwing-MingTai Chi Fighting Set: Two-Person Matching Set (2004, YMAA Publication Center), el DVD recientemente producido por Michael Gilman ofrece otra mirada hacia esta práctica poco común que forma parte del currículum del estilo Yang
Tai Chi Fighting Set: Two-Person Matching Set
Yang Jwing-Ming. Roslindale, MA: YMAA Publication Center, 2004. 120 minutos. Vídeo casete
Dissolved Microcystin Release Coincident with Lysis of a Bloom Dominated by Microcystis spp. in Western Lake Erie Attributed to a Novel Cyanophage
Western Lake Erie (Laurentian Great Lakes) is prone to annual cyano- bacterial harmful algal blooms (cHABs) dominated by Microcystis spp. that often yield microcystin toxin concentrations exceeding the federal EPA recreational con-tact advisory of 8 μg liter-1. In August 2014, microcystin levels were detected in fin-ished drinking water above the World Health Organization 1.0 μg liter-1 threshold for consumption, leading to a 2-day disruption in the supply of drinking water for \u3e400,000 residents of Toledo, Ohio (USA). Subsequent metatranscriptomic analysis of the 2014 bloom event provided evidence that release of toxin into the water sup-ply was likely caused by cyanophage lysis that transformed a portion of the intracel-lular microcystin pool into the dissolved fraction, rendering it more difficult to elimi-nate during treatment. In August 2019, a similar increase in dissolved microcystins at the Toledo water intake was coincident with a viral lytic event caused by a phage consortium different in composition from what was detected following the 2014 To-ledo water crisis. The most abundant viral sequence in metagenomic data sets was a scaffold from a putative member of the Siphoviridae, distinct from the Ma-LMM01-like Myoviridae that are typically documented to occur in western Lake Erie. This study provides further evidence that viral activity in western Lake Erie plays a signifi-cant role in transformation of microcystins from the particulate to the dissolved frac-tion and therefore requires monitoring efforts from local water treatment plants. Ad-ditionally, identification of multiple lytic cyanophages will enable the development of a quantitative PCR toolbox to assess viral activity during cHABs. IMPORTANCE Viral attack on cHABs may contribute to changes in community com-position during blooms, as well as bloom decline, yet loss of bloom biomass does not eliminate the threat of cHAB toxicity. Rather, it may increase risks to the public by delivering a pool of dissolved toxin directly into water treatment utilities when the dominating Microcystis spp. are capable of producing microcystins. Detecting, characterizing, and quantifying the major cyanophages involved in lytic events will assist water treatment plant operators in making rapid decisions regarding the pool of microcystins entering the plant and the corresponding best practices to neutralize the toxin
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A Genome-Wide RNAi Screen in Caenorhabditis elegans Identifies the Nicotinic Acetylcholine Receptor Subunit ACR-7 as an Antipsychotic Drug Target
We report a genome-wide RNA interference (RNAi) screen for Suppressors of Clozapine-induced Larval Arrest (scla genes) in Caenorhabditis elegans, the first genetic suppressor screen for antipsychotic drug (APD) targets in an animal. The screen identifies 40 suppressors, including the α-like nicotinic acetylcholine receptor (nAChR) homolog acr-7. We validate the requirement for acr-7 by showing that acr-7 knockout suppresses clozapine-induced larval arrest and that expression of a full-length translational GFP fusion construct rescues this phenotype. nAChR agonists phenocopy the developmental effects of clozapine, while nAChR antagonists partially block these effects. ACR-7 is strongly expressed in the pharynx, and clozapine inhibits pharyngeal pumping. acr-7 knockout and nAChR antagonists suppress clozapine-induced inhibition of pharyngeal pumping. These findings suggest that clozapine activates ACR-7 channels in pharyngeal muscle, leading to tetanus of pharyngeal muscle with consequent larval arrest. No APDs are known to activate nAChRs, but a number of studies indicate that α7-nAChR agonists may prove effective for the treatment of psychosis. α-like nAChR signaling is a mechanism through which clozapine may produce its therapeutic and/or toxic effects in humans, a hypothesis that could be tested following identification of the mammalian ortholog of C. elegans acr-7
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