3,412 research outputs found
Involvement of the Rcs regulon in the persistence of Salmonella Typhimurium in tomatoes
It is becoming clear that human enteric pathogens, like Salmonella, can efficiently colonize vegetative and reproductive organs of plants. Even though the bacterium's ability to proliferate within plant tissues has been linked to outbreaks of salmonellosis, little is known about regulatory and physiological adaptations of Salmonella, or other human pathogens, to their persistence in plants. A screen of Salmonella deletion mutants in tomatoes identified rcsA and rcsB genes as those under positive selection. In tomato fruits, populations of Salmonella rcsB mutants were as much as 100-fold lower than those of the wild type. In the follow-up experiments, competitive fitness of rcsA and rcsB mutants was strongly reduced in tomatoes. Bioinformatics predictions identified a putative Salmonella RcsAB binding box (TTMGGAWWAABCTYA) and revealed an extensive putative RcsAB regulon, of which many members were differentially fit within tomatoes
High-precision estimate of g4 in the 2D Ising model
We compute the renormalized four-point coupling in the 2d Ising model using
transfer-matrix techniques. We greatly reduce the systematic uncertainties
which usually affect this type of calculations by using the exact knowledge of
several terms in the scaling function of the free energy. Our final result is
g4=14.69735(3).Comment: 17 pages, revised version with minor changes, accepted for
publication in Journal of Physics
Irrelevant operators in the two-dimensional Ising model
By using conformal-field theory, we classify the possible irrelevant
operators for the Ising model on the square and triangular lattices. We analyze
the existing results for the free energy and its derivatives and for the
correlation length, showing that they are in agreement with the conformal-field
theory predictions. Moreover, these results imply that the nonlinear scaling
field of the energy-momentum tensor vanishes at the critical point. Several
other peculiar cancellations are explained in terms of a number of general
conjectures. We show that all existing results on the square and triangular
lattice are consistent with the assumption that only nonzero spin operators are
present.Comment: 32 pages. Added comments and reference
Neon and Sulfur Abundances of Planetary Nebulae in the Magellanic Clouds
The chemical abundances of neon and sulfur for 25 planetary nebulae (PNe) in
the Magellanic Clouds are presented. These abundances have been derived using
mainly infrared data from the Spitzer Space Telescope. The implications for the
chemical evolution of these elements are discussed. A comparison with similarly
obtained abundances of Galactic PNe and HII regions and Magellanic Clouds HII
regions is also given. The average neon abundances are 6.0x10(-5) and
2.7x10(-5) for the PNe in the Large and Small Magellanic Clouds respectively.
These are ~1/3 and 1/6 of the average abundances of Galactic planetary nebulae
to which we compare. The average sulfur abundances for the LMC and SMC are
respectively 2.7x10(-6) and 1.0x10(-6). The Ne/S ratio (23.5) is on average
higher than the ratio found in Galactic PNe (16) but the range of values in
both data sets is similar for most of the objects. The neon abundances found in
PNe and HII regions agree with each other. It is possible that a few (3-4) of
the PNe in the sample have experienced some neon enrichment, but for two of
these objects the high Ne/S ratio can be explained by their very low sulfur
abundances. The neon and sulfur abundances derived in this paper are also
compared to previously published abundances using optical data and
photo-ionization models.Comment: 13 pages, 4 tables, 5 figures. Accepted for publication in Ap
Critical energy flux and mass in solvable theories of 2d dilaton gravity
In this paper we address the issue of determining the semiclassical threshold
for black hole formation in the context of a one-parameter family of theories
which continuously interpolates between the RST and BPP models. We find that
the results depend significantly on the initial static configuration of the
spacetime geometry before the influx of matter is turned on. In some cases
there is a critical energy density, given by the Hawking rate of evaporation,
as well as a critical mass (eventually vanishing). In others there is
neither nor a critical flux.Comment: LaTeX file, 12 pages, 4 figure
Black Hole Formation by Sine-Gordon Solitons in Two-dimensional Dilaton Gravity
The CGHS model of two-dimensional dilaton gravity coupled to a sine-Gordon
matter field is considered. The theory is exactly solvable classically, and the
solutions of a kink and two-kink type solitons are studied in connection with
black hole formation.Comment: 11 pages, no figures, revte
Cosmological bounds on neutrino statistics
We consider the phenomenological implications of the violation of the Pauli exclusion principle for neutrinos, focusing on cosmological observables such as the spectrum of Cosmic Microwave Background anisotropies, Baryon Acoustic Oscillations and the primordial abundances of light elements. Neutrinos that behave (at least partly) as bosonic particles have a modified equilibrium distribution function that implies a different influence on the evolution of the Universe that, in the case of massive neutrinos, can not be simply parametrized by a change in the effective number of neutrinos. Our results show that, despite the precision of the available cosmological data, only very weak bounds can be obtained on neutrino statistics, disfavouring a more bosonic behaviour at less than 2sigma
Relativistic quantum mechanics of a Dirac oscillator
The Dirac oscillator is an exactly soluble model recently introduced in the
context of many particle models in relativistic quantum mechanics. The model
has been also considered as an interaction term for modelling quark confinement
in quantum chromodynamics. These considerations should be enough for
demonstrating that the Dirac oscillator can be an excellent example in
relativistic quantum mechanics. In this paper we offer a solution to the
problem and discuss some of its properties. We also discuss a physical picture
for the Dirac oscillator's non-standard interaction, showing how it arises on
describing the behaviour of a neutral particle carrying an anomalous magnetic
moment and moving inside an uniformly charged sphere.Comment: 19 pages, 1 figur
Thermalisation of sterile neutrinos in the early universe in the 3+1 scheme with full mixing matrix
In the framework of a 3+1 scheme with an additional inert state, we consider the thermalisation of sterile neutrinos in the early Universe taking into account the full 4×4 mixing matrix. The evolution of the neutrino energy distributions is found solving the momentum-dependent kinetic equations with full diagonal collision terms, as in previous analyses of flavour neutrino decoupling in the standard case. The degree of thermalisation of the sterile state is shown in terms of the effective number of neutrinos, Neff, and its dependence on the three additional mixing angles (θ_14, θ_24, θ_34) and on the squared mass difference Δm^2_41 is discussed. Our results are relevant for fixing the contribution of a fourth light neutrino species to the cosmological energy density, whose value is very well constrained by the final Planck analysis. For the preferred region of active-sterile mixing parameters from short-baseline neutrino experiments, we find that the fourth state is fully thermalised (Neff≃4)
Mitochondrial echoes of first settlement and genetic continuity in El Salvador
Background: From Paleo-Indian times to recent historical episodes, the Mesoamerican isthmus played an important role in the distribution and patterns of variability all around the double American continent. However, the amount of genetic information currently available on Central American continental populations is very scarce. In order to shed light on the role of Mesoamerica in the peopling of the New World, the present study focuses on the analysis of the mtDNA variation in a population sample from El Salvador.
Methodology/Principal Findings: We have carried out DNA sequencing of the entire control region of the mitochondrial DNA (mtDNA) genome in 90 individuals from El Salvador. We have also compiled more than 3,985 control region profiles from the public domain and the literature in order to carry out inter-population comparisons. The results reveal a predominant Native American component in this region: by far, the most prevalent mtDNA haplogroup in this country (at ~90%) is A2, in contrast with other North, Meso- and South American populations. Haplogroup A2 shows a star-like phylogeny and is very diverse with a substantial proportion of mtDNAs (45%; sequence range 16090–16365) still unobserved in other American populations. Two different Bayesian approaches used to estimate admixture proportions in El Salvador shows that the majority of the mtDNAs observed come from North America. A preliminary founder analysis indicates that the settlement of El Salvador occurred about 13,400±5,200 Y.B.P.. The founder age of A2 in El Salvador is close to the overall age of A2 in America, which suggests that the colonization of this region occurred within a few thousand years of the initial expansion into the Americas.
Conclusions/Significance: As a whole, the results are compatible with the hypothesis that today's A2 variability in El Salvador represents to a large extent the indigenous component of the region. Concordant with this hypothesis is also the observation of a very limited contribution from European and African women (~5%). This implies that the Atlantic slave trade had a very small demographic impact in El Salvador in contrast to its transformation of the gene pool in neighbouring populations from the Caribbean facade
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