28,400 research outputs found
Recommended from our members
Actor perception in business use case modeling
Mainstream literature recognizes the validity and effectiveness of use cases as a technique for gathering and capturing system requirements. Use cases represent the driver of various modern development methods, mainly of object-oriented extraction, such as the Unified Process. Although the adoption of use cases proliferated in the context of software systems development, they are not as extensively employed in business modeling . The concept of business use case is not a novelty, but only recently did it begin to re-circulate in the literature and in case tools.
This paper examines the issues involved in adopting business use cases for capturing the functionality of an organization and proposes guidelines for their identification, packaging, and mapping to system use cases. The proposed guidelines are based on the principle of actor perception described in the paper. The application of this principle is exemplified with a worked example aimed at demonstrating the utility of the proposed guidelines and at clarifying the application of the principle of actor perception. The worked example is based on a series of workshops run at a major UK financial institution
Glassy correlations and microstructures in randomly crosslinked homopolymer blends
We consider a microscopic model of a polymer blend that is prone to phase
separation. Permanent crosslinks are introduced between randomly chosen pairs
of monomers, drawn from the Deam-Edwards distribution. Thereby, not only
density but also concentration fluctuations of the melt are quenched-in in the
gel state, which emerges upon sufficient crosslinking. We derive a Landau
expansion in terms of the order parameters for gelation and phase separation,
and analyze it on the mean-field level, including Gaussian fluctuations. The
mixed gel is characterized by thermal as well as time-persistent (glassy)
concentration fluctuations. Whereas the former are independent of the
preparation state, the latter reflect the concentration fluctuations at the
instant of crosslinking, provided the mesh size is smaller than the correlation
length of phase separation. The mixed gel becomes unstable to microphase
separation upon lowering the temperature in the gel phase. Whereas the length
scale of microphase separation is given by the mesh size, at least close to the
transition, the emergent microstructure depends on the composition and
compressibility of the melt. Hexagonal structures, as well as lamellae or
random structures with a unique wavelength, can be energetically favorable.Comment: 19 pages, 10 figures. Submitted to the Journal of Chemical Physics
(http://jcp.aip.org
Cosmological Implications of a Non-Separable 5D Solution of the Vacuum Einstein Field Equations
An exact class of solutions of the 5D vacuum Einstein field equations (EFEs)
is obtained. The metric coefficients are found to be non-separable functions of
time and the extra coordinate and the induced metric on = constant
hypersurfaces has the form of a Friedmann-Robertson-Walker cosmology. The 5D
manifold and 3D and 4D submanifolds are in general curved, which distinguishes
this solution from previous ones in the literature. The singularity structure
of the manifold is explored: some models in the class do not exhibit a big
bang, while other exhibit a big bang and a big crunch. For the models with an
initial singularity, the equation of state of the induced matter evolves from
radiation like at early epochs to Milne-like at late times and the big bang
manifests itself as a singular hypersurface in 5D. The projection of comoving
5D null geodesics onto the 4D submanifold is shown to be compatible with
standard 4D comoving trajectories, while the expansion of 5D null congruences
is shown to be in line with conventional notions of the Hubble expansion.Comment: 8 pages, in press in J. Math. Phy
Draft genome sequence of Pseudomonas moraviensis R28-S
We report the draft genome sequence of Pseudomonas moraviensis R28-S, isolated from the municipal wastewater treatment plant of Moscow, ID. The strain carries a native mercury resistance plasmid, poorly maintains introduced IncP-1 antibiotic resistance plasmids, and has been useful for studying the evolution of plasmid host range and stability
Adiabatic-Nonadiabatic Transition in the Diffusive Hamiltonian Dynamics of a Classical Holstein Polaron
We study the Hamiltonian dynamics of a free particle injected onto a chain
containing a periodic array of harmonic oscillators in thermal equilibrium. The
particle interacts locally with each oscillator, with an interaction that is
linear in the oscillator coordinate and independent of the particle's position
when it is within a finite interaction range. At long times the particle
exhibits diffusive motion, with an ensemble averaged mean-squared displacement
that is linear in time. The diffusion constant at high temperatures follows a
power law D ~ T^{5/2} for all parameter values studied. At low temperatures
particle motion changes to a hopping process in which the particle is bound for
considerable periods of time to a single oscillator before it is able to escape
and explore the rest of the chain. A different power law, D ~ T^{3/4}, emerges
in this limit. A thermal distribution of particles exhibits thermally activated
diffusion at low temperatures as a result of classically self-trapped polaronic
states.Comment: 15 pages, 4 figures Submitted to Physical Review
On the ordeal of quinolone preparation via cyclisation of aryl-enamines; synthesis and structure of ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)-quinoline-3-carboxylate
Recent studies directed to the design of compounds targeting the bc(1) protein complex of Plasmodium falciparum, the parasite responsible for most lethal cases of malaria, identified quinolones (4-oxo-quinolines) with low nanomolar inhibitory activity against both the enzyme and infected erythrocytes. The 4-oxo-quinoline 3-ester chemotype emerged as a possible source of potent bc(1) inhibitors, prompting us to expand the library of available analogs for SAR studies and subsequent lead optimization. We now report the synthesis and structural characterization of unexpected ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)quinoline-3-carboxylate, a 4-aryloxy-quinoline 3-ester formed during attempted preparation of 6-methyl-7-iodo-4-oxo-quinoline-3-carboxylate (4-oxo-quinoline 3-ester). We propose that the 4-aryloxy-quinoline 3-ester derives from 6-methyl-7-iodo-4-hydroxy-quinoline-3-carboxylate (4-hydroxy-quinoline 3-ester), the enol form of 6-methyl-7-iodo-4-oxo-quinoline-3-carboxylate. Formation of the 4-aryloxy-quinoline 3-ester confirms the impact of quinolone/hydroxyquinoline tautomerism, both on the efficiency of synthetic routes to quinolones and on pharmacologic profiles. Tautomers exhibit different cLogP values and interact differently with the enzyme active site. A structural investigation of 6-methyl-7-iodo-4-oxo-quinoline-3-carboxylate and 6-methyl-7-iodo-4-hydroxy-quinoline-3-carboxylate, using matrix isolation coupled to FTIR spectroscopy and theoretical calculations, revealed that the lowest energy conformers of 6-methyl-7-iodo-4-hydroxy-quinoline-3-carboxylate, lower in energy than their most stable 4-oxo-quinoline tautomer by about 27 kJ mol(-1), are solely present in the matrix, while the most stable 4-oxo-quinoline tautomer is solely present in the crystalline phase.Fundacao para a Ciencia e Tecnologia (FCT - Portugal) [UID/Multi/04326/2013]; QREN-COMPETE-UE; CCMAR; FCT [SFRH/BD/81821/2011, RECI/BBB-BQB/0230/2012, UI0313/QUI/2013, UID/FIS/04564/2016]; FEDER/COMPETE-UE; [PTDC/QEQ-QFI/3284/2014 - POCI-01-0145-FEDER-016617]info:eu-repo/semantics/publishedVersio
Four-dimensional topological Einstein-Maxwell gravity
The complete on-shell action of topological Einstein-Maxwell gravity in
four-dimensions is presented. It is shown explicitly how this theory for SU(2)
holonomy manifolds arises from four-dimensional Euclidean N=2 supergravity. The
twisted local BRST symmetries and twisted local Lorentz symmetries are given
and the action and stress tensor are shown to be BRST-exact. A set of
BRST-invariant topological operators is given. The vector and antisymmetric
tensor twisted supersymmetries and their algebra are also found.Comment: Published version. Expanded discussion of new results in the
introduction and some clarifying remarks added in later sections. 22 pages,
uses phyzz
Cluster Ellipticities as a Cosmological Probe
We investigate the dependence of ellipticities of clusters of galaxies on
cosmological parameters using large-scale cosmological simulations. We
determine cluster ellipticities out to redshift unity for LCDM models with
different mean densities and amplitudes of mass fluctuation
. The mean ellipticity increases monotonically with redshift for
all models. Larger values of , i.e., earlier cluster formation
time, produce lower ellipticities. The dependence of ellipticity on
is relatively weak in the range for high mass
clusters. The mean ellipticity decreases linearly with the
amplitude of fluctuations at the cluster redshift , nearly independent of
; on average, older clusters are more relaxed and are thus less
elliptical. The distribution of ellipticities about the mean is approximated by
a Gaussian, allowing a simple characterization of the evolution of ellipticity
with redshift as a function of cosmological parameters. At , the mean
ellipticity of high mass clusters is approximated by . This relation opens up the
possibility that, when compared with future observations of large cluster
samples, the mean cluster ellipticity and its evolution could be used as a new,
independent tool to constrain cosmological parameters, especially the amplitude
of mass fluctuations, .Comment: 16 pages, 4 figure
Legendrian Distributions with Applications to Poincar\'e Series
Let be a compact Kahler manifold and a quantizing holomorphic
Hermitian line bundle. To immersed Lagrangian submanifolds of
satisfying a Bohr-Sommerfeld condition we associate sequences , where is a
holomorphic section of . The terms in each sequence concentrate
on , and a sequence itself has a symbol which is a half-form,
, on . We prove estimates, as , of the norm
squares in terms of . More generally, we show that if and
are two Bohr-Sommerfeld Lagrangian submanifolds intersecting
cleanly, the inner products have an
asymptotic expansion as , the leading coefficient being an integral
over the intersection . Our construction is a
quantization scheme of Bohr-Sommerfeld Lagrangian submanifolds of . We prove
that the Poincar\'e series on hyperbolic surfaces are a particular case, and
therefore obtain estimates of their norms and inner products.Comment: 41 pages, LaTe
- …