Developments of the pinned photodiode terahertz rectifier

This paper presents we presents a development of the structure of the pinned photodiode terahertz rectifier, in which the metal whisker of the antenna is separated from the semiconductor by a silane oxide layer, in order to reduce the surface defectiveness. The rectifies is the basic component of an image detection system based on the structure of actual CMOS image detectors. The structure combines a nano-antenna, fabricated on the top of a standard image sensor, the rectifier, and the readout electronics. The rectifier device proposed has vertical extension of some tenths of nanometers, can be created at the foot of the nano-whisker at the end of the terahertz antenna, above the storage well

Noise-induced macroscopic bifurcations in globally-coupled chaotic units

Large populations of globally-coupled identical maps subjected to independent additive noise are shown to undergo qualitative changes as the features of the stochastic process are varied. We show that for strong coupling, the collective dynamics can be described in terms of a few effective macroscopic degrees of freedom, whose deterministic equations of motion are systematically derived through an order parameter expansion.Comment: Phys. Rev. Lett., accepte

The Kuramoto model with distributed shear

We uncover a solvable generalization of the Kuramoto model in which shears (or nonisochronicities) and natural frequencies are distributed and statistically dependent. We show that the strength and sign of this dependence greatly alter synchronization and yield qualitatively different phase diagrams. The Ott-Antonsen ansatz allows us to obtain analytical results for a specific family of joint distributions. We also derive, using linear stability analysis, general formulae for the stability border of incoherence.Comment: 6 page

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). The exploration of the chemical space around the main functional groups led to the discovery of selective hCA IX inhibitors in the micromolar/nanomolar range, thus establishing robust structure-activity relationships within this versatile scaffold. HPLC separation of some selected chiral compounds and biological evaluation of the corresponding enantiomers was performed along with molecular modelling studies on the most active derivatives

Tocilizumab administration in COVID-19 patients: Water on the fire or gasoline?

Tocilizumab is widely being used to treat COVID-19. Although reducing systemic inflammation, it also increases the risk for secondary infections as a result of the immunosuppression produced. We report the case of a 69-year-old patient admitted to the ICU with severe respiratory distress caused by COVID-19 pneumonia who developed pulmonary aspergillosis. On the basis of these findings, we suggest early testing for pulmonary aspergillosis in COVID-19 patients treated with tocilizumab

Produção de matéria seca e teores de nitrogênio em milho para silagem adubado com uréia misturada a zeólita.

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Platelet-rich gel for the adjuvant treatment of wound healing of transposed flap for arteriovenous fistula in systemic scleroderma

LETTER TO EDITO

CASSCF and MR–CISD study of the n−4s and n−4pe Rydberg states of the CF3Cl

AbstractThe low-lying n−4s (S2 and T2) and n−4pe (S3 and T3) Rydberg states of the CF3Cl have been studied at the CASSCF, MR–CISD, MR–CISD+Q and MR–AQCC levels using the mixed aug–cc–pVDZ/d–aug–cc–pVDZ and aug′–cc–pVTZ/d′–aug′–cc–pVTZ basis sets. Spin–orbit corrections for the singlet energies, vertical excitation energies and oscillator strengths have been computed. The effect of the inclusion of K+L or only the K inner shell chlorine orbitals in the frozen core space at the post-CASSCF levels has also been discussed. Good agreement with available experimental and with previous high-level theoretical results has been achieved