A comprehensive characterization of Hermetia illucens derived chitosan produced through homogeneous deacetylation

The increasing demand for chitin and chitosan is driving research to explore alternative sources to crustaceans. Insects, particularly bioconverters as Hermetia illucens, are promising substitutes as they process food industry waste into valuable molecules, including chitin. Chitosan can be produced by chitin deacetylation: hot deacetylation to obtain a heterogeneous chitosan, the commonly produced, and cold deacetylation to obtain a homogeneous chitosan, not widely available. The two different treatments lead to a different arrangement of the amine and acetyl groups in the chitosan structure, affecting its molecular weight, deacetylation degree, and biological activity. This is the first report on the production and chemical-physical and biological characterization of homogenous chitosan derived from H. illucens larvae, pupal exuviae, and adults. This work, in addition to the report on heterogeneous chitosan by our research group, completes the overview of H. illucens chitosan. The yield values obtained for homogeneous chitosan from pupal exuviae (3 and 7 %) are in the range of insect (2–8 %) and crustaceans (4–15 %) chitosan. The evaluation of the antioxidant activity and antimicrobial properties against Gram-negative (Escherichia coli) and Gram-positive (Micrococcus flavus) bacteria confirmed the great versatility of H. illucens chitosan for biomedical and industrial applications and its suitability as an alternative source to crustaceans

Papier-mach(in)e: Thinking with “sticky” paper in the cloud

There is nothing less about paper and its use when it comes to academic study as we experience increasingly converging media spaces and functionalities of online applications within the screens of our laptops, mobile phones and tablet devices. The paper persists, and the paperless office, classroom and pedagogy become nothing but pure rhetoric. Hence, it is most pertinent to focus on paper and its “stickiness” in maintaining educational structures and practices. Usually hidden from view or neglected in educational technology studies is a consideration on how we think and interact not only with our mind but also with our heads and limbs. This paper will argue that paper has a composite place or bearing, a kind of stickiness to our technologised bodies, digital mobilities and hybrid practices in what I have coined here as papier-mach(in)e. This claim will be supported by evidence that demonstrates how we simply think both practically and pathically and that our mobilities in media and physical spaces are in one form or another meshed with paper. In fact, a drive towards a paperless classroom or pedagogy is without much foundation when it comes to mobilising a sustainable agenda for technology-enhanced learning

Five-Year Outcome After Continuous Flow LVAD With Full-Magnetic (HeartMate 3) Versus Hybrid Levitation System (HeartWare): A Propensity-Score Matched Study From an All-Comers Multicentre Registry

Despite the withdrawal of the HeartWare Ventricular Assist Device (HVAD), hundreds of patients are still supported with this continuous-flow pump, and the long-term management of these patients is still under debate. This study aims to analyse 5 years survival and freedom from major adverse events in patients supported by HVAD and HeartMate3 (HM3). From 2010 to 2022, the MIRAMACS Italian Registry enrolled all-comer patients receiving a LVAD support at seven Cardiac Surgery Centres. Out of 447 LVAD implantation, 214 (47.9%) received HM3 and 233 (52.1%) received HVAD. Cox-regression analysis adjusted for major confounders showed an increased risk for mortality (HR 1.5 [1.2–1.9]; p = 0.031), for both ischemic stroke (HR 2.08 [1.06–4.08]; p = 0.033) and haemorrhagic stroke (HR 2.6 [1.3–4.9]; p = 0.005), and for pump thrombosis (HR 25.7 [3.5–188.9]; p < 0.001) in HVAD patients. The propensity-score matching analysis (130 pairs of HVAD vs. HM3) confirmed a significantly lower 5 years survival (81.25% vs. 64.1%; p 0.02), freedom from haemorrhagic stroke (90.5% vs. 70.1%; p < 0.001) and from pump thrombosis (98.5% vs. 74.7%; p < 0.001) in HVAD cohort. Although similar perioperative outcome, patients implanted with HVAD developed a higher risk for mortality, haemorrhagic stroke and thrombosis during 5 years of follow-up compared to HM3 patients

Measurement of the atmospheric muon flux with the NEMO Phase-1 detector

The NEMO Collaboration installed and operated an underwater detector including prototypes of the critical elements of a possible underwater km3 neutrino telescope: a four-floor tower (called Mini-Tower) and a Junction Box. The detector was developed to test some of the main systems of the km3 detector, including the data transmission, the power distribution, the timing calibration and the acoustic positioning systems as well as to verify the capabilities of a single tridimensional detection structure to reconstruct muon tracks. We present results of the analysis of the data collected with the NEMO Mini-Tower. The position of photomultiplier tubes (PMTs) is determined through the acoustic position system. Signals detected with PMTs are used to reconstruct the tracks of atmospheric muons. The angular distribution of atmospheric muons was measured and results compared with Monte Carlo simulations.Comment: Astrop. Phys., accepte

NEMO: A Project for a km3^3 Underwater Detector for Astrophysical Neutrinos in the Mediterranean Sea

The status of the project is described: the activity on long term characterization of water optical and oceanographic parameters at the Capo Passero site candidate for the Mediterranean km$^3$ neutrino telescope; the feasibility study; the physics performances and underwater technology for the km$^3$; the activity on NEMO Phase 1, a technological demonstrator that has been deployed at 2000 m depth 25 km offshore Catania; the realization of an underwater infrastructure at 3500 m depth at the candidate site (NEMO Phase 2).Comment: Proceeding of ISCRA 2006, Erice 20-27 June 200

All-sky Search for High-Energy Neutrinos from Gravitational Wave Event GW170104 with the ANTARES Neutrino Telescope

Advanced LIGO detected a significant gravitational wave signal (GW170104) originating from the coalescence of two black holes during the second observation run on January 4$^{\textrm{th}}$, 2017. An all-sky high-energy neutrino follow-up search has been made using data from the ANTARES neutrino telescope, including both upgoing and downgoing events in two separate analyses. No neutrino candidates were found within $\pm500$ s around the GW event time nor any time clustering of events over an extended time window of $\pm3$ months. The non-detection is used to constrain isotropic-equivalent high-energy neutrino emission from GW170104 to less than $\sim4\times 10^{54}$ erg for a $E^{-2}$ spectrum

The ANTARES Collaboration: Contributions to ICRC 2017 Part I: Neutrino astronomy (diffuse fluxes and point sources)

Papers on neutrino astronomy (diffuse fluxes and point sources, prepared for the 35th International Cosmic Ray Conference (ICRC 2017, Busan, South Korea) by the ANTARES Collaboratio

The ANTARES Collaboration: Contributions to ICRC 2017 Part III: Searches for dark matter and exotics, neutrino oscillations and detector calibration

Papers on the searches for dark matter and exotics, neutrino oscillations and detector calibration, prepared for the 35th International Cosmic Ray Conference (ICRC 2017, Busan, South Korea) by the ANTARES Collaboratio

The ANTARES Collaboration: Contributions to ICRC 2017 Part II: The multi-messenger program

Papers on the ANTARES multi-messenger program, prepared for the 35th International Cosmic Ray Conference (ICRC 2017, Busan, South Korea) by the ANTARES Collaboratio

URBAN CENTER. Una casa di vetro per le politiche urbane.

Nella cultura di governo della città, il termine "Urban Center" (o "Casa della città") designa una serie di strutture il cui denominatore comune risiede nello svolgimento di attività di servizio per le comunità urbane ai fini di soddisfare la crescente domenda di democrazia partecipativa e deliberativa nei processi di trasformazione degli insediamenti. Traendo spunto dalla storicizzazione del fenomeno e dal confronto tra i consolidati modelli statunitensi e le recenti esperienze in Italia, il volume si interroga sulla maturazione delle missioni dell' "Urban Center" nel passaggio da asettico spazio di informazione a luogo provilegiato per la costruzione trasparente di politiche urbane condivise. Il percorso logico del volume si sviluppa seguendo un fil rouge articolato in quattro parti. Il primo blocco si apre con due tematiche che costituiscono dialetticamente la cornice di riferimento entro cui può essere correttamente collocata la questione degli UC: l’urbanistica partecipata e il marketing urbano. Nella seconda parte attraverso lo studio di casi si ricostruisce il quadro delle articolate declinazioni statunitensi di Urban Center, consolidatesi in diversi decenni di storia. Sono strutture fortemente caratterizzate e autonome per stile, missioni, obiettivi, priorità, modalità operative, ma allo stesso tempo accomunate da un equilibrato mix di passione civile e pragmatismo professionale. Il terzo gruppo di saggi è dedicato alla condizione attuale e di prospettiva degli UC in Italia, delineando criticamente una sorta di “mappa dinamica” delle diverse strutture attivate e in divenire, caratterizzate per soggetti ispiratori, missioni “stili” e protagonismo degli attori coinvolti. Il cerchio delle riflessioni si chiude nella quarta parte discutendo la questione dell’innovazione di metodo per la costruzione di un UC sia attraverso la dimensione teoretica che le potenzialità operative. Testi in italiano e inglese di B. Monardo (curatore), M.C. Bizzarri, E. Carmagnani, M. Carta, F. Ceci, P. Colarossi, L. De Bonis, A. Dina, A. De Rossi, D. Filippi, A. Giorgi, P. Laconte, F. Lovato, L. J. Osmond, R. Shiffman, O Tommasi, A. Uttaro; postfazione di M. Ricci