152 research outputs found
Field-induced Ordering in Critical Antiferromagnets
Transfer-matrix scaling methods have been used to study critical properties
of field-induced phase transitions of two distinct two-dimensional
antiferromagnets with discrete-symmetry order parameters: triangular-lattice
Ising systems (TIAF) and the square-lattice three-state Potts model (SPAF-3).
Our main findings are summarised as follows. For TIAF, we have shown that the
critical line leaves the zero-temperature, zero -field fixed point at a finite
angle. Our best estimate of the slope at the origin is . For SPAF-3 we provided evidence that the zero-field correlation
length diverges as , with , through analysis of the critical curve at plus crossover
arguments. For SPAF-3 we have also ascertained that the conformal anomaly and
decay-of-correlations exponent behave as: (a) H=0: ; (b) .Comment: RevTex, 7 pages, 4 eps figures, to be published in Phys. Rev.
The Critical Behaviour of the Spin-3/2 Blume-Capel Model in Two Dimensions
The phase diagram of the spin-3/2 Blume-Capel model in two dimensions is
explored by conventional finite-size scaling, conformal invariance and Monte
Carlo simulations. The model in its -continuum Hamiltonian version is
also considered and compared with others spin-3/2 quantum chains. Our results
indicate that differently from the standard spin-1 Blume-Capel model there is
no multicritical point along the order-disorder transition line. This is in
qualitative agreement with mean field prediction but in disagreement with
previous approximate renormalization group calculations. We also presented new
results for the spin-1 Blume-Capel model.Comment: latex 18 pages, 4 figure
Nail surface topography and onychochronobiology.
Peer reviewe
Short-Range Ising Spin Glass: Multifractal Properties
The multifractal properties of the Edwards-Anderson order parameter of the
short-range Ising spin glass model on d=3 diamond hierarchical lattices is
studied via an exact recursion procedure. The profiles of the local order
parameter are calculated and analysed within a range of temperatures close to
the critical point with four symmetric distributions of the coupling constants
(Gaussian, Bimodal, Uniform and Exponential). Unlike the pure case, the
multifractal analysis of these profiles reveals that a large spectrum of the
-H\"older exponent is required to describe the singularities of the
measure defined by the normalized local order parameter, at and below the
critical point. Minor changes in these spectra are observed for distinct
initial distributions of coupling constants, suggesting an universal spectra
behavior. For temperatures slightly above T_{c}, a dramatic change in the
function is found, signalizing the transition.Comment: 8 pages, LaTex, PostScript-figures included but also available upon
request. To be published in Physical Review E (01/March 97
Spanning forests and the q-state Potts model in the limit q \to 0
We study the q-state Potts model with nearest-neighbor coupling v=e^{\beta
J}-1 in the limit q,v \to 0 with the ratio w = v/q held fixed. Combinatorially,
this limit gives rise to the generating polynomial of spanning forests;
physically, it provides information about the Potts-model phase diagram in the
neighborhood of (q,v) = (0,0). We have studied this model on the square and
triangular lattices, using a transfer-matrix approach at both real and complex
values of w. For both lattices, we have computed the symbolic transfer matrices
for cylindrical strips of widths 2 \le L \le 10, as well as the limiting curves
of partition-function zeros in the complex w-plane. For real w, we find two
distinct phases separated by a transition point w=w_0, where w_0 = -1/4 (resp.
w_0 = -0.1753 \pm 0.0002) for the square (resp. triangular) lattice. For w >
w_0 we find a non-critical disordered phase, while for w < w_0 our results are
compatible with a massless Berker-Kadanoff phase with conformal charge c = -2
and leading thermal scaling dimension x_{T,1} = 2 (marginal operator). At w =
w_0 we find a "first-order critical point": the first derivative of the free
energy is discontinuous at w_0, while the correlation length diverges as w
\downarrow w_0 (and is infinite at w = w_0). The critical behavior at w = w_0
seems to be the same for both lattices and it differs from that of the
Berker-Kadanoff phase: our results suggest that the conformal charge is c = -1,
the leading thermal scaling dimension is x_{T,1} = 0, and the critical
exponents are \nu = 1/d = 1/2 and \alpha = 1.Comment: 131 pages (LaTeX2e). Includes tex file, three sty files, and 65
Postscript figures. Also included are Mathematica files forests_sq_2-9P.m and
forests_tri_2-9P.m. Final journal versio
Lattice gauge theory with baryons at strong coupling
We study the effective Hamiltonian for strong-coupling lattice QCD in the
case of non-zero baryon density. In leading order the effective Hamiltonian is
a generalized antiferromagnet. For naive fermions, the symmetry is U(4N_f) and
the spins belong to a representation that depends on the local baryon number.
Next-nearest-neighbor (nnn) terms in the Hamiltonian break the symmetry to
U(N_f) x U(N_f). We transform the quantum problem to a Euclidean sigma model
which we analyze in a 1/N_c expansion. In the vacuum sector we recover
spontaneous breaking of chiral symmetry for the nearest-neighbor and nnn
theories. For non-zero baryon density we study the nearest-neighbor theory
only, and show that the pattern of spontaneous symmetry breaking depends on the
baryon density.Comment: 31 pages, 5 EPS figures. Corrected Eq. (6.1
Transcranial direct current stimulation facilitates motor learning post-stroke: a systematic review and meta-analysis.
Transcranial direct current stimulation (tDCS) is an attractive protocol for stroke motor recovery. The current systematic review and meta-analysis investigated the effects of tDCS on motor learning post-stroke. Specifically, we determined long-term learning effects by examining motor improvements from baseline to at least 5 days after tDCS intervention and motor practise. 17 studies reported long-term retention testing (mean retention interval=43.8 days; SD=56.6 days) and qualified for inclusion in our meta-analysis. Assessing primary outcome measures for groups that received tDCS and motor practise versus sham control groups created 21 valid comparisons: (1) 16 clinical assessments and (2) 5 motor skill acquisition tests. A random effects model meta-analysis showed a significant overall effect size=0.59 (p<0.0001; low heterogeneity, T(2)=0.04; I(2)=22.75%; and high classic fail-safe N=240). 4 moderator variable analyses revealed beneficial effects of tDCS on long-term motor learning: (1) stimulation protocols: anodal on the ipsilesional hemisphere, cathodal on the contralesional hemisphere, or bilateral; (2) recovery stage: subacute or chronic stroke; (3) stimulation timing: tDCS before or during motor practise; and (4) task-specific training or conventional rehabilitation protocols. This robust meta-analysis identified novel long-term motor learning effects with tDCS and motor practise post-stroke
Human Nail Plate Modifications Induced by Onychomycosis : Implications for Topical Therapy
Open Access - This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are creditedConclusions: Onchomycotic nails presented a thicker but more porous barrier, and its eroded intracellular matrix rendered the tissue more permeable to topically applied chemicals when an aqueous vehicle was used.Purpose: Through the characterisation of the human onchomycotic nail plate this study aimed to inform the design of new topical ungual formulations.Methods: The mechanical properties of the human nail were characterised using a Lloyd tensile strength tester. The nail’s density was determined via pycnometry and the nail’s ultrastructure by electron microscopy. Raman spectroscopy analysed the keratin disulphide bonds within the nail and its permeability properties were assessed by quantifying water and rhodamine uptake.Results: Chronic in vivo nail plate infection increased human nailplate thickness (healthy 0.49 ± 0.15 mm; diseased 1.20 ± 0.67 mm), but reduced its tensile strength (healthy 63.7 ± 13.4 MPa; diseased 41.7 ± 5.0 MPa) and density (healthy 1.34 ± 0.01 g/cm3; diseased 1.29 ± 0.00 g/cm3). Onchomycosis caused cell-cell separation, without disrupting the nail disulfide bonds or desmosomes. The diseased and healthy nails showed equivalent water uptake profiles, but the rhodamine penetration was 4-fold higher in the diseased nails using a PBS vehicle and 3 -fold higher in an ethanol/PBS vehicle.Peer reviewe
Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of β-Thalassemia and Sickle-Cell Anemia
The objective of this review is to present examples of lead compounds identified from biological material (fungi, plant extracts and agro-industry material) and of possible interest in the field of a pharmacological approach to the therapy of β-thalassemia using molecules able to stimulate production of fetal hemoglobin (HbF) in adults. Concerning the employment of HbF inducers as potential drugs for pharmacological treatment of β-thalassemia, the following conclusions can be reached: (i) this therapeutic approach is reasonable, on the basis of the clinical parameters exhibited by hereditary persistence of fetal hemoglobin patients, (ii) clinical trials (even if still limited) employing HbF inducers were effective in ameliorating the symptoms of β-thalassemia patients, (iii) good correlation of in vivo and in vitro results of HbF synthesis and γ-globin mRNA accumulation indicates that in vitro testing might be predictive of in vivo responses and (iv) combined use of different inducers might be useful to maximize HbF, both in vitro and in vivo. In this review, we present three examples of HbF inducers from the natural world: (i) angelicin and linear psoralens, contained in plant extracts from Angelica arcangelica and Aegle marmelos, (ii) resveratrol, a polyphenol found in grapes and several plant extracts and (iii) rapamycin, isolated from Streptomyces hygroscopicus
Adults with autism overestimate the volatility of the sensory environment.
Insistence on sameness and intolerance of change are among the diagnostic criteria for autism spectrum disorder (ASD), but little research has addressed how people with ASD represent and respond to environmental change. Here, behavioral and pupillometric measurements indicated that adults with ASD are less surprised than neurotypical adults when their expectations are violated, and decreased surprise is predictive of greater symptom severity. A hierarchical Bayesian model of learning suggested that in ASD, a tendency to overlearn about volatility in the face of environmental change drives a corresponding reduction in learning about probabilistically aberrant events, thus putatively rendering these events less surprising. Participant-specific modeled estimates of surprise about environmental conditions were linked to pupil size in the ASD group, thus suggesting heightened noradrenergic responsivity in line with compromised neural gain. This study offers insights into the behavioral, algorithmic and physiological mechanisms underlying responses to environmental volatility in ASD
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