164 research outputs found
Looking Back and Moving Forward: A History and Discussion of Privately Practising Midwives in Western Australia
The aim of this historical narrative research study was to fill a gap in the literature by investigating, analysing and describing the history of privately practising midwives in Western Australia (WA) from colonisation to the present day (approximately 1830-2018). This study embedded within a naturalistic, feminist paradigm analysed oral history interviews from fifteen midwives and three doctors, and archival documents to reconstruct the history, and explore the experiences of privately practising midwives in WA
Evaluation of diagnostic tests for Trypanosoma evansi and their application in epidemiological studies in Indonesia
The diagnosis of Trypanosoma evansi infections is problematic because low, fluctuating
parasitaemias are typical of sub-acute and chronic infections. Antigen-detection ELlSAs
(Ag-ELISAs) that have been developed to detect trypanosomal antigens in serum are reported to be
better indicators of current T. evansi infections than either parasitological or antibody-detection tests.
Two T. evansi Ag-ELISAs based on different monoclonal antibodies (2G6 Ag-ELISA and
Tr7 Ag-ELISA) were evaluated using buffaloes in Southeast Asia, where T. evansi is endemic and
livestock are important for draught power, meat and investment. The two Ag-ELISAs were
standardised in the UK, following international guidelines on data expression and quality assurance.
Diagnostic sensitivities were estimated using buffaloes either experimentally infected (n=35) or
naturally infected (n=l 39) with T. evansi and compared with estimates obtained for the
microhaematocrit test (MHCT), mouse inoculation (MI), three antibody-detection tests (IgM ELISA,
IgG ELISA and card agglutination test {CATT}). Diagnostic specificities were estimated with nonexposed British cattle (n=249) and Australian buffaloes (n=263), and positive and negative
predictive values were calculated. Field studies were conducted in Central Java to estimate
prevalence and true incidence rates of T. evansi infections in buffaloes. No previous studies have
compared two T. evansi Ag-ELISAs, estimated the prevalence of T. evansi infections in multiple
villages within a district or true incidence rates.The repeatability and robustness of the two Ag-ELISAs were shown to be high. Profiles of
antigenaemia varied between individual buffaloes and between the two Ag-ELISAs. Antigen and
antibody responses were first detected 7 to 42 days after infection, but in some buffaloes responses
fluctuated below cut-off values during infection, whilst in other buffaloes antigen and antibody
responses persisted after trypanocidal drug treatment. With the naturally-infected buffaloes, the
diagnostic sensitivity estimate of the Tr7 Ag-ELISA (81%) was significantly higher than that of the
2G6 Ag-ELISA (71%), and the IgG ELISA sensitivity (89%) was significantly higher than either the
IgM ELISA or CATT sensitivities (78%). The diagnostic specificity estimates obtained with the
British cattle were 83% for the 2G6 Ag-ELISA and 78% for the Tr7 Ag-ELISA, and with the
Australian buffaloes were 75% for the 2G6 Ag-ELISA, 78% for the Tr7 Ag-ELISA, 100% for the
CATT, 89% for the IgM ELISA and 92% for the IgG ELISA. Only slight agreement was found
between the two Ag-ELISAs (kappa = 0.20), but moderate agreement between the IgG ELISA and
CATT (kappa = 0.58). Positive and negative predictive values ranged from 24% to 99% for
prevalence values from 10% to 90%, and true prevalence was underestimated at higher test
prevalence values and overestimated at lower test prevalence valuesIn Central Java, 2387 buffaloes were blood sampled in 59 villages, and estimates of test
prevalence were 4% with the MHCT, 9% with MI, 58% with the 2G6 Ag-ELISA and 70% with the
Tr7 Ag-ELISA, but prevalence values differed between districts and between villages. True incidence
rates per animal-year at risk were 0.44 with the Tr7 Ag-ELISA and 0.22 with the 2G6 Ag-ELISA.
Of 239 market buffaloes sampled, 10% were parasitaemic, 39% antigenaemic, 56% positive by IgG
ELISA and 47% positive by CATT, representing an important source of T. evansi.The T. evansi Ag-ELISAs and antibody-detection tests used in this study have many
advantages as screening tests over commonly used parasitological tests, in terms of their diagnostic
sensitivity and ability to rapidly test large numbers of samples. The two T. evansi Ag-ELISAs could
be applied in high prevalence areas, whilst antibody-detection tests (in particular, the IgG ELISA or
CATT) would be more appropriate to test buffaloes in low prevalence areas or to confirm the
negative-status of buffaloes prior to movement within Indonesia or export. Future work should aim to
improve the specificities of the Ag-ELISAs, which were low in this study in contrast to previous
reports. The CATT had a high positive predictive value even with low prevalence and could be
adapted more readily to test individual buffaloes in the field. The selection of diagnostic tests for
T. evansi depends not only on test validity parameters, but also on the prevalence of T. evansi in the
test population, the principal testing objectives and practical consideration
Does midwifery-led care demonstrate care ethics: A template analysis
Background: Ethical care in maternity is fundamental to providing care that both prevents harm and does good, and yet, there is growing acknowledgement that disrespect and abuse routinely occur in this context, which indicates that current ethical frameworks are not adequate. Care ethics offers an alternative to the traditional biomedical ethical principles. Research aim: The aim of the study was to determine whether a correlation exists between midwifery-led care and care ethics as an important first step in an action research project. Research design: Template analysis was chosen for this part of the action research. Template analysis is a design that tests theory against empirical data, which requires pre-set codes. Participants and context: A priori codes that represent midwifery-led care were generated by a stakeholder consultative group of nine childbearing women using nominal group technique, collected in Perth, Western Australia. The a priori codes were applied to a predesigned template with four domains of care ethics. Ethical considerations: Ethics approval was granted by the Edith Cowan University research ethics committee REMS no. 2019-00296-Buchanan. Findings: The participants generated eight a priori codes representing ethical midwifery care, such as: 1.1 Relationship with Midwife; 1.2 Woman-centred care; 2.1 Trust women’s bodies and abilities; 2.2. Protect normal physiological birth; 3.1. Information provision; 3.2. Respect autonomy; 4.1. Birth culture of fear (midwifery-led care counter-cultural) and 4.2. Recognition of rite of passage. The a priori codes were mapped to the care ethics template. The template analysis found that midwifery-led care does indeed demonstrate care ethics. Discussion: Care ethics takes into consideration what principle-based bioethics have previously overlooked: relationship, context and power. Conclusion: Midwifery-led care has been determined in this study to demonstrate care ethics, which suggest that further research is defensible with the view that it could be incorporated into the ethical codes and conduct for the midwifery profession
Physiological plateaus during normal labor and birth: A novel definition
Background: Diagnoses of labor dystocia, and subsequent labor augmentation, make one of the biggest contributions to childbirth medicalization, which remains a key challenge in contemporary maternity care. However, labor dystocia is poorly defined, and the antithetical concept of physiological plateaus remains insufficiently explored. Aim: To generate a definition of physiological plateaus as a basis for further research. Methods: This qualitative study applied grounded theory methods and comprised interviews with 20 midwives across Australia, conducted between September 2020 and February 2022. Data were coded in a three-phase approach, starting with inductive line-by-line coding, which generated themes and subthemes, and finally, through axial coding. Results: Physiological plateaus represent a temporary slowing of one or multiple labor processes and appear to be common during childbirth. They are reported throughout the entire continuum of labor, typically lasting between a few minutes to several hours. Their etiology/function appears to be a self-regulatory mechanism of the mother-infant dyad. Physiological plateaus typically self-resolve and are followed by a self-resumption of labor. Women with physiological plateaus during labor appear to experience positive birth outcomes. Discussion: Despite appearing to be common, physiological plateaus are insufficiently recognized in contemporary childbirth discourse. Consequently, there seems to be a significant risk of misinterpretation of physiological plateaus as labor dystocia. While findings are limited by the qualitative design and require validation through further quantitative research, the proposed novel definition provides an important starting point for further investigation. Conclusion: A better understanding of physiological plateaus holds the potential for a de-medicalization of childbirth through preventing unjustified labor augmentation
Care ethics framework for midwifery practice: A scoping review
Background: As a normative theory, care ethics has become widely theorized and accepted. However, there remains a lack of clarity in relation to its use in practice, and a care ethics framework for practice. Maternity care is fraught with ethical issues and care ethics may provide an avenue to enhance ethical sensitivity. Aim: The purpose of this scoping review is to determine how care ethics is used amongst health professions, and to collate the information in data charts to create a care ethics framework and definition for midwifery practice. Method: The scoping review was conducted according to the Preferred Reporting Items for Scoping reviews (PRISMA-ScR) and Joanna Briggs Institute (JBI) recommendations. The search was applied to the databases CINAHL, MEDLINE, PschInfo and Pubmed which were searched in September 2019 and again in July 2021. The inclusion criteria were guided by the mnemonic for search terms: Participants, Concept, and Context (PCC) and included variations of health care professionals, care ethics and utilization. The search was limited to qualitative studies published in English between 2010 and 2021. A data extraction tool was used to extract and synthesize data into categories. The articles were screened for eligibility by title, abstract and full text review, by two independent reviewers. Ethical Considerations: The scoping review was guided by ethical conduct respecting authorship and referencing sources. Results: Twelve of the initially identified 129 studies were included in the scoping review. Data synthesis yielded four categories of care ethics use by health professionals: relationship, context, attention to power and caring practices. In combination, the evidence forms a framework for care ethics use in midwifery practice. Conclusion: Care ethics use by health professionals enhances ethical sensitivity. A framework and definition for care ethics for midwifery practice is proposed. This review will be of interest to midwives and other health practitioners seeking to enhance ethical sensitivity
Care ethics framework for midwifery practice: A scoping review
Background: As a normative theory, care ethics has become widely theorized and accepted. However, there remains a lack of clarity in relation to its use in practice, and a care ethics framework for practice. Maternity care is fraught with ethical issues and care ethics may provide an avenue to enhance ethical sensitivity.
Aim: The purpose of this scoping review is to determine how care ethics is used amongst health professions, and to collate the information in data charts to create a care ethics framework and definition for midwifery practice.
Method: The scoping review was conducted according to the Preferred Reporting Items for Scoping reviews (PRISMA-ScR) and Joanna Briggs Institute (JBI) recommendations. The search was applied to the databases CINAHL, MEDLINE, PschInfo and Pubmed which were searched in September 2019 and again in July 2021. The inclusion criteria were guided by the mnemonic for search terms: Participants, Concept, and Context (PCC) and included variations of health care professionals, care ethics and utilization. The search was limited to qualitative studies published in English between 2010 and 2021. A data extraction tool was used to extract and synthesize data into categories. The articles were screened for eligibility by title, abstract and full text review, by two independent reviewers.
Ethical Considerations: The scoping review was guided by ethical conduct respecting authorship and referencing sources.
Results: Twelve of the initially identified 129 studies were included in the scoping review. Data synthesis yielded four categories of care ethics use by health professionals: relationship, context, attention to power and caring practices. In combination, the evidence forms a framework for care ethics use in midwifery practice.
Conclusion: Care ethics use by health professionals enhances ethical sensitivity. A framework and definition for care ethics for midwifery practice is proposed. This review will be of interest to midwives and other health practitioners seeking to enhance ethical sensitivity
Failure to progress or just normal? A constructivist grounded theory of physiological plateaus during childbirth
Background and problem: During childbirth, one of the most common diagnoses of pathology is ‘failure to progress’, frequently resulting in labour augmentation and intervention cascades. However, failure to progress is poorly defined and evidence suggests that some instances of slowing, stalling and pausing labour patterns may represent physiological plateaus. Aim: To explore how midwives conceptualise physiological plateaus and the significance such plateaus may have for women\u27s labour trajectory and birth outcome. Methods: Twenty midwives across Australia participated in semi-structured interviews between September 2020 and February 2022. Constructivist grounded theory methodology was applied to analyse data, including multi-phasic coding and application of constant comparative methods, resulting in a novel theory of physiological plateaus that is firmly supported by participant data. Findings: This study found that the conceptualisation of plateauing labour depends largely on health professionals’ philosophical assumptions around childbirth. While the Medical Dominant Paradigm frames plateaus as invariably pathological, the Holistic Midwifery Paradigm acknowledges plateaus as a common and valuable element of labour that serves a self-regulatory purpose and results in good birth outcomes for mother and baby. Discussion: Contemporary medicalised approaches in maternity care, which are based on an expectation of continuous labour progress, appear to carry a risk for a misinterpretation of physiological plateaus as pathological. Conclusion: This study challenges the widespread bio-medical conceptualisation of plateauing labour as failure to progress, encourages a renegotiation of what can be considered healthy and normal during childbirth, and provides a stimulus to acknowledge the significance of childbirth philosophy for maternity care practice
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An extreme value theory approach to calculating minimum capital risk requirements
This paper investigates the frequency of extreme events for three LIFFE futures contracts for
the calculation of minimum capital risk requirements (MCRRs). We propose a semiparametric
approach where the tails are modelled by the Generalized Pareto Distribution and
smaller risks are captured by the empirical distribution function. We compare the capital
requirements form this approach with those calculated from the unconditional density and
from a conditional density - a GARCH(1,1) model. Our primary finding is that both in-sample
and for a hold-out sample, our extreme value approach yields superior results than either of
the other two models which do not explicitly model the tails of the return distribution. Since
the use of these internal models will be permitted under the EC-CAD II, they could be widely
adopted in the near future for determining capital adequacies. Hence, close scrutiny of
competing models is required to avoid a potentially costly misallocation capital resources
while at the same time ensuring the safety of the financial system
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