24 research outputs found
Silurian graptolite biostratigraphy of the Röstånga-1 drill core, Scania:a standard for southern Scandinavia
The Rostanga-1 core from west-central Scania provides the most complete succession of the Sandbian (Upper Ordovician) through lower Telychian (Silurian, Llandovery) strata of southern Scandinavia. The Hirnantian is identified in the Kallholn Formation by the presence of a Metabolograptus persculptus Biozone fauna. The Akidograptus ascensus, Parakidograptus acuminatus, Cystograptus vesiculosus and Monograptus revolutus biozones can be differentiated in the Rhuddanian. Following a considerable gap (Demirastrites triangulatus Biozone to a level within the Pribylograptus leptotheca Biozone), the succession resumes. The Aeronian also includes the Lituigraptus convolutus and Stimulograptus sedgwickii biozones. The Stimulograptus halli Biozone appears to be missing, but the Telychian Spirograptus guerichi to Streptograptus crispus biozones have been recognized
A Cambrian–Ordovician boundary section in the Rafnes–Herøya submarine tunnel, Skien–Langesund District, southern Norway
Rock specimens and contained fossils collected in 1976 from a submarine tunnel driven between Herøya and Rafnes in the Skien–Langesund area of southern Norway, have been restudied. The contained fossils include olenid and agnostoid trilobites, graptolites and brachiopods, groups described in detail for the first time from the area and documenting a Cambrian–Ordovician boundary section unique in the district where the upper Cambrian Alum Shale Formation is elsewhere overlain by the Middle Ordovician Rognstranda Member of the Huk Formation (Kundan in terms of Baltoscandian chronostratigraphy). The hiatus at the base of the Huk Formation is thus smaller in the section described herein, beginning at a level within rather than below the Tremadocian. Estimated thickness of the Alum Shale includes 10–12 m of Miaolingian and 20–22 m of Furongian strata with trilobite zones identified, and a Tremadocian section of 8.1 m identified by species of the dendroid graptolite Rhabdinopora in the basal 2.6 m and Bryograptus ramosus at the top. The Tremadocian section is preserved in a postulated zone of synsedimentary subsidence along the Porsgrunn–Kristiansand Fault Zone, while at the same time there was extensive erosion across an emergent, level platform elsewhere in the Skien–Langesund District and the southern part of the Eiker–Sandsvær District to the north. Aspects of stratigraphy and tectonics are highlighted together with a discussion on the Cambrian– Ordovician boundary locally and worldwide
Marketing e empreendedorismo: uma relação umbilical
Este relatório, ao constatar a diferente aplicabilidade dos conhecimentos e utensÃlios de
marketing, devido às empresas maduras e de maior dimensão desfrutarem de recursos que os
empreendedores e gestores de pequenas empresas não possuem, tem como objetivo, baseado
na experiencia profissional do autor e respetivo enquadramento teórico e cientÃfico,
caracterizar a relação entre o marketing e o empreendedorismo, permitindo uma melhor
compreensão das alternativas existentes para os empreendedores e gestores de pequenas
empresas, além de uma identificação dos seus comportamentos e atitudes mais recorrentes.
Neste contexto, ganha preponderância uma reflexão sobre o marketing empreendedor, como
ocorre e em que circunstâncias pode auxiliar o empreendedor a tomar decisões e
simultaneamente não perder competitividade para os seus potenciais concorrentes. Assim, a
comunicação boca-a-boca, o cÃrculo de influências do empreendedor e as redes sociais
inovadoras, são cada vez mais consideradas e reconhecidas como garante de competitividade e
inovação, num ambiente empresarial em constante mudança; ABSTRACT: This report, observes the different applicability of the knowledge and marketing tools,
justified by the existence of bigger possessions that mature companies have, comparing to the
resources that the entrepreneurs and managers of small companies do not own. This report,
based in the professional experience of the author and theoretical and scientific knowledge,
aims to characterize the connection between marketing and the entrepreneurship, allowing a
better understanding of the alternatives and behaviors that entrepreneurs and managers of
small companies could take, in order to compete with their rivals. In this context, it gains
prominence a reflection on the entrepreneurial marketing, when it occurs and which
circumstances can assist the entrepreneur to take decisions in order to not lose competitiveness
for its potential opponents. Thus, the buzz communication, the circle of influences of the
entrepreneur and the new social networks, are each time more considered and recognized as it
guarantees of competitiveness and innovation, in an enterprise environment constantly in
change
An academic challenge to the entrepreneurial university: the spatial power of the ‘Slow Swimming Club’
© 2018 Society for Research into Higher Education. The entrepreneurial university is a vague notion that has evolved by applying the concepts of enterprise and entrepreneurship to a university context. The blurring of enterprise with entrepreneurship has allowed the entrepreneurial university to be increasingly underpinned by a managerialist discourse, typified by functionalisation and marketisation; culminating in academic disempowerment, dissatisfaction and subsequent disengagement. In response to such dissatisfaction, this paper reflects on a playful space, called the Slow Swimming Club (SSC), produced by several academics. The research takes a collective auto-ethnographic approach and employs Foucault’s heterotopology, as a conceptual frame, to understand the collective impact of this SSC entrepreneuring space. We relate the disconnection of the SSC to the process of critically connecting academics, back to their universities and consider whether such academic resistance, rooted in play, corporeal sensibility and emancipation, has the potential to enact social change and enhance entrepreneurial potential
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049