3 research outputs found
Formation of Carbon–Carbon Bonds Using Aminal Radicals
Aminal radicals were generated by radical translocation processes. For the first time, it is shown that they participate in carbon–carbon bond forming reactions. Either stannane or silane hydrogen atom donors are suitable for the reaction. More than 30 substrate combinations are reported, and chemical yields are as high as 91%
Predicting Electrocatalytic Properties: Modeling Structure–Activity Relationships of Nitroxyl Radicals
Stable
nitroxyl radical-containing compounds, such as 2,2,6,6-tetramethylpiperidine-<i>N</i>-oxyl (TEMPO) and its derivatives, are capable of electrocatalytically
oxidizing a wide range of alcohols under mild and environmentally
friendly conditions. Herein, we examine the structure–function
relationships that determine the catalytic activity of a diverse range
of water-soluble nitroxyl radical compounds. A strong correlation
is described between the difference in the electrochemical oxidation
potentials of a compound and its electrocatalytic activity. Additionally,
we construct a simple computational model that is able to accurately
predict the electrochemical potential and catalytic activity of a
wide range of nitroxyl radical derivatives
Predicting Electrocatalytic Properties: Modeling Structure–Activity Relationships of Nitroxyl Radicals
Stable
nitroxyl radical-containing compounds, such as 2,2,6,6-tetramethylpiperidine-<i>N</i>-oxyl (TEMPO) and its derivatives, are capable of electrocatalytically
oxidizing a wide range of alcohols under mild and environmentally
friendly conditions. Herein, we examine the structure–function
relationships that determine the catalytic activity of a diverse range
of water-soluble nitroxyl radical compounds. A strong correlation
is described between the difference in the electrochemical oxidation
potentials of a compound and its electrocatalytic activity. Additionally,
we construct a simple computational model that is able to accurately
predict the electrochemical potential and catalytic activity of a
wide range of nitroxyl radical derivatives