22 research outputs found
Penerapan Model Pembelajaran Kooperatif Tipe Think Pair Share (Tps) Dan Teknik Mencatat Mind Mapping Sebagai Upaya Meningkatkan Hasil Belajar Fisika
Penelitian ini merupakan penelitian tindakan kelas yang dilaksanakan dalam tiga siklus bertujuan untuk mengetahui aktivitas belajar dan hasil belajar ma h a siswa pada materi Kalor. Subjek dalam penelitian ini adalah ma h a siswaprogram studi pendidikan biologi yang berjumlah 13 orang. Data yang diperoleh dari tes dan lembar observasi dianalisis dengan menggunakan statistik deskriptif.Hasil penelitian (a) hasil belajar siswa terdiri dari aspek pemahaman konsep dan aspek kinerja ilmiah. Untuk aspek pemahaman konsep pada siklus I dengan nilai rata-rata 60,58 dan ketuntasan belajar 15,38 % (belum tuntas), pada siklus IIdengan nilai rata-rata 66,35 dan ketuntasan belajar 76,92 % (tuntas), dan pada siklus III dengan nilai rata-rata 74,81 dan ketuntasan belajar 92,31 % (tuntas)
Fault Modelling Based on Local Magnetic Anomaly Data in Geothermal Prospect Area Rajabasa Lampung
Two and half dimensions fault modelling was conducted based on Local Magnetic Anomaly Data in Mount Rajabasa site, Lampung. The research utilized total magnetic anomaly secondary data to perform quantitative interpretation. The total magnetic anomaly data was then transformed into flat field, reduced to a pole and carried upward continuation until at an altitude of 4000 MSL to separate local anomaly and regional anomaly. Based on the qualitative interpretation of the anomalous magnetic field, it indicates a normal fault with the direction of northeast – southwest and northwest – southeast. In the research, quantitative interpretation was done to local anomaly by selecting two locations that showed the presence of lineament patterns in the contour. Modelling was conducted by using Mag2DC software. By modelling those two sites, was obtained that fault model that is located in Mount Rajabasa area is a normal fault trending northwest – southeast with the value of magnetic susceptibility contrast of 0.004 and -0.015 in cgs unit
The Reevaluation of MIBI as the Ligand of 99mTc-MIBI Radiopharmaceutical for Myocardial Imaging
Methoxy isobutyl isonitrile labelled with technetium-99m (99mTc) radionuclide can be used for the evaluation of acute myocardial infarction. The 99mTc-MIBI radiopharmaceutical is available in the lyophilized-kit, which is separately packed with its radionuclide. Recently, in CNTMR-BATAN Bandung, 99mTc-MIBI radiopharmaceutical was prepared using MIBI ligand synthesized in 1996 as lyophilized-kits having the radiochemical purity less than 90 % and not accumulated in the myocardium. It could be caused by several factors, among others were technical preparation of lyophilized dry-kit and the quality of MIBI; therefore the reevaluation of the ligand for the quality improvement was needed. Firstly, MIBI ligand was recristallized. It was found that MIBI as [Cu(MIBI)4]BF4 salt was a glassy solid with the melting point of 98 -99 oC. The infra red analysis showed the presence of spectra vibration at 1085, 1180 cm-1 and 2180, 2220 cm-1 for –OCH3 and N≡C groups, respectively. The preparation of 99mTc-MIBI was performed by adding 99mTc radionuclide into new MIBI liquid-kit, then boiled in water bath for minimum period of 10 minutes. The radiochemical purity of 99mTc-MIBI was analysed by thin layer chromatographic method using absolute ethanol as a mobile phase. The pre-clinical evaluation was observed in Wistar rat and clinical studies were performed in volunter using gamma camera. It is revealed that the radiochemical purity of more than 90 % i.e. 96.83 ± 1.43 % was still stable until 24 hours storage at room temperature. The stability studies of 99mTc-MIBI in human blood plasma showed that in 6 hours, the radiochemical purity was decreased to 90.89 ± 2.90 %. Clinical application of 99mTc-MIBI with tomography techniques using gamma camera showed the distinct accumulation of radioactivity in the heart
The Reevaluation of MIBI as the Ligand of 99mTc-MIBI Radiopharmaceutical for Myocardial Imaging
Methoxy isobutyl isonitrile labelled with technetium-99m (99mTc) radionuclide can be used for the evaluation of acute myocardial infarction. The 99mTc-MIBI radiopharmaceutical is available in the lyophilized-kit, which is separately packed with its radionuclide. Recently, in CNTMR-BATAN Bandung, 99mTc-MIBI radiopharmaceutical was prepared using MIBI ligand synthesized in 1996 as lyophilized-kits having the radiochemical purity less than 90 % and not accumulated in the myocardium. It could be caused by several factors, among others were technical preparation of lyophilized dry-kit and the quality of MIBI; therefore the reevaluation of the ligand for the quality improvement was needed. Firstly, MIBI ligand was recristallized. It was found that MIBI as [Cu(MIBI)4]BF4 salt was a glassy solid with the melting point of 98 -99 oC. The infra red analysis showed the presence of spectra vibration at 1085, 1180 cm-1 and 2180, 2220 cm-1 for –OCH3 and N≡C groups, respectively. The preparation of 99mTc-MIBI was performed by adding 99mTc radionuclide into new MIBI liquid-kit, then boiled in water bath for minimum period of 10 minutes. The radiochemical purity of 99mTc-MIBI was analysed by thin layer chromatographic method using absolute ethanol as a mobile phase. The pre-clinical evaluation was observed in Wistar rat and clinical studies were performed in volunter using gamma camera. It is revealed that the radiochemical purity of more than 90 % i.e. 96.83 ± 1.43 % was still stable until 24 hours storage at room temperature. The stability studies of 99mTc-MIBI in human blood plasma showed that in 6 hours, the radiochemical purity was decreased to 90.89 ± 2.90 %. Clinical application of 99mTc-MIBI with tomography techniques using gamma camera showed the distinct accumulation of radioactivity in the heart
Pengaruh Model Pembelajaran Make a Match Terhadap Hasil Belajar Kognitif Fisika Siswa Di Smk Negeri 1 Bangun Purba Kabupaten Rokan Hulu
This research aimed to determine the effect of learning models make a match against physics student learning outcomes. This research was conducted in SMK 1 Bangun Purba. This type of research is true experimental design. This research design control group pre-test post-test. The population in this study a class XI student as much as 2 class with a sampling technique in this study is saturated sampling. Analysis of the data, using the N gain test, test for normality, homogeneity test and t test. The results of the t-test calculations showed that 4.740> 2.024. It can be concluded that there are significant learning model make a match against the cognitive learning physics class XI student of SMK 1 Bangun Purba with a level of 95%
The Effect of Calcium Carbonate and Cholecalciferol on Pharmacokinetic Interaction of 99mTc-CTMP Radiopharmaceuticals for Bone Scanning in Rats (Rattus norvegicus)
Hypocalcemia is one of manifestation of bone metastases which could be treated  using calcium carbonate and cholecalciferol. Tc-99m radiolabeled 1,4,8,11-tetraazacyclo tetradecyl-1,4,8,11-tetramethylene phosponic acid(against 99mTc-CTMP)on the other hand is a radioactive complex compound which has an affinity toward bone. Therefore, it could be used as bone tracer (radiopharmaceutical) in bone imaging.However, there has been a concern regarding the use 99mTc-CTMPon patients who have been treated with calcium carbonate and cholecalciferol. In this circumstance 99mTc-CTMPcould interact withcalcium carbonate and cholecalciferol and it might then interefere with the imaging results. Therefore, the aim of this study was to determine the pharmacokinetic behavior of 99mTc-CTMP in rats (Rattus norvegicus)that had been previously treated with calcium carbonate and cholecalciferol. The pharmacokineticstudies were performed using four groups of animal modeland each groups consists of three rats. The groups were classified as control (I), rats treated with calcium carbonate (II), rats treated with cholecalciferol (III), and rats treated with both calcium carbonate and cholecalciferol (IV). After the rats were treated for 3 days,99mTc-CTMP radiopharmaceutical was injected through a tail vein of each rat. At specific time intervals after 99mTc-CTMP administration, blood wasthen extracted from the tail, weighedand counted using a single channel analyzer. The percentage of radioactivity in blood at a certain interval wasthen calculated to determine the distribution half-time and the elimination half-time. Thedistribution half-time of group I, II, II, and IV were 0.43+0.13, 0.25+0.18, 0.32+0.10, and 0.47+0.07 hours, respectively, while the elimination half-time were 2.56+0.18, 4.48+0.56, 4.47+1.13, 6.19+1.97 respectively. The results of T-test showed that there was no significant difference of distribution half-time between the three treated groups and the control group. However, there was significant difference of elimination half-time between the three treatment groups and control. This research showed that giving calcium carbonate or, cholecalciferol, and both for 3 days prior administration of 99mTc-CTMP would mantain elimination half-time which resulted in longer excretion/ elimination time
Labeling of the Recombinant Streptokinase Using Iodine-131 as a New Thrombolytic Agent
Stroke and acute myocardial infarction is a disease with the highest mortality in the world. WHO has estimated in 2008, 30% of deaths from heart disease and more than 80% of this cases have been occurred in developing countries. Streptokinase (SK) as an effective thrombolytic agent has been used as a drug of choice for about forty years ago. SK is plasminogen (PG) activator that converts plasminogen to active protease, called plasmin (PN) which degrades fibrin to soluble products. Recombinant streptokinase (SKA) from genetic engineering has been developed at School of Pharmacy ITB to reduce or eliminate immunogenicity of SK. However, scientific disclosures relating to dynamic and its kinetic studies in the body have still to be proven. One method that can explain this phenomenon is the pharmacological studies using radionuclide labeled compounds. Radioiodine labeled compound is used extensively and most suitable for biological studies. This paper describes the preparation of 131I-SKA and its characterization. The labeling conditions of SKA, such as chloramine-T as an oxidizing agent, amount of SKA, incubation time, and size of resin to purify the labeling yield have been observed. The result showed that the optimum condition of labeling (35.11%) was obtained using 10 µg of chloramine-T and 60 seconds of incubation time. The highest radiochemical purity (97.46 ± 1.14%) has also been obtained by passing through the resin chromatography column using 100 mg Dowex 1x8, size 50-100 mesh. The characterization of 131I-SKA with SDS PAGE method and autoradiography showed the similar performance with unlabeled-SKA.Received: 04 December 2012; Revised: 20 December 2012; Accepted: 21 December 201
Persepsi Siswa Tentang Perhatian Orang Tua Terhadap Prestasi Belajar Fisika Siswa Kelas XI Mia3 SMA N 2 Ujungbatu Kab. Rokan Hulu
Penelitian ini membahas tentang persepsi siswa tentang perhatian orang tua terhadap prestasi belajar fisika siswa. Sampel dalam penelitian ini seluruh siswa kelas XI MIA3 SMA N 2 Ujungbatu yang berjumlah 28 siswa. Hasil penelitian menunjukkan terdapat korelasi positif antara perhatian orang tua terhadap prestasi belajar fisika siswa ditunjukkan nilai rtabel<rhitung, 0,374 < 0,99 dengan persamaan regresi Y = 60,95 + 0,225 X dengan arah koefisien regresi linier = 0,43 bertanda positif. Perhatian orang tua berpengaruh terhadap prestasi belajar fisika siswa kelas XI MIA3 SMA N 2 Ujungbatu dari segi indikator pengawasan belajar anak sebesar 34,06% dan sisanya dipengaruhi indikator lain