70 research outputs found

    Ethnographical study : use of new media technologies in a Finnish change consultancy company

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    In this study, I investigated how new media technologies were used in a Finnish change consultancy company. Ethnographical method was applied to study the question. I spent four months in a change consultancy company doing observation and actively participating in a company everyday life. As a part of ethnography, nine semi-structured interviews were carried out on all the company members. The concept of domestication was used in this research to study the use of new media technologies in a company. This concept has been presented in the researches for over twenty five years most significantly in England and Scandinavian countries. In addition, the concept of affects and emotions was used. I followed the researches who do not distinguish affect and emotion. I concentrated on the positive affects such as enthusiasm, enjoyment, satisfaction, happiness, joy. During the workshops new media technologies were not used intensively. However, the way they were used supported in creating the unique working atmosphere and environment. New media technologies were used to create and extend the affects. There were not so many devices that the workers used on a daily basis at work. When they talked about the use of new media, they talked more about practical use like storing the information. The main characteristics of new media – creativity, interactivity and freedom were not realized by all of them. The “reminder” phenomenon has an important meaning in my research. The clients become excited, “hot” during the workshops but there is a danger that they might become “cold” after the workshop if there is no any kind of contact with them

    Formal differentiated approach to managing women with stress urinary incontinence

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    ABSTRACT The object of research: treatment of women with stress urinary incontinence (SUI). Investigated problem: substantiation of the choice of treatment methods in the management of women of different ages with SUI depending on the urogynecological status, age, financial capabilities, risk of complications and speed of achieving the desired result. The main scientific results: An approach has been developed to substantiate the most rational method of treatment of women of different ages with SUI, taking into account the provision of an adequate standard of living. It is based on the use of hierarchy analysis, which allows to determine the priorities between competing treatments - mid-urethral sling (MUS), pelvic floor muscle training (PFMT) and containment (absorbent pads). The expediency of applying a formal differentiated approach is confirmed by the results of questionnaires of representative groups of women on the technology of UDI-6 and IIQ-7 questionnaires before and after treatment. It is recommended to choose a rational method of treatment or a set of treatment methods personally depending on the urogynecological status, age, financial capabilities, risk of complications and speed of achieving the desired result. MUS has gained the highest number of points due to the short time of treatment and rehabilitation, long-term postoperative effect, accessibility, low level of complications and significant improvement of life quality in young and elderly women. The most rational method of treatment of middle-aged patients with SUI is the method of PFMT as one that has a positive impact on the life quality of women and does not require financial costs. The area of practical use of the research results: medical institutions providing urogynecological care to women. Innovative technological product: development of a formal differentiated approach to the management of women with SUI, which allows to choose the most rational method of treatment taking into account the life quality. Scope of the innovative technological product: clinical practice of treatment of women with SUI

    Determination of atmospheric air pollution by physical and chemical characteristics of snowmelt

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     The state of the environment in cities is determined by the degree of pollution of individual components of the environment. Geochemical anomalies in urban agglomerations are often formed in pollution depositing media such as soil, snow cover, bottom sediments. The purpose of the study is environmental monitoring of anthropogenic impact in diff erent areas of Smolensk and Vyazma according to the physical and chemical characteristics of melted snow. Snow was chosen as the object of the study, because it accumulates many substances entering the atmosphere, and subsequently can become a source of secondary pollution of the soil cover, underground and surface waters. The study determined organoleptic parameters (smell, color, turbidity, the presence of sediment in melt water), chemical parameters (the number of suspended particles, pH, total rigidity and mineralization, the amount of organic substances).The presence of chloride ions (Cl- ), sulfate ions (SO4 2-), nitrate ions (NO3-), nitrite ions (NO2 - ), bicarbonate ions (HCO3 - ) and ions of some heavy metals (Pb2+, Cu2+, Fe3+) have been determined. Bioindication of the studied samples on watercress has been carried out in parallel. A low level of air pollution in Smolensk and Vyazma has been established. The greatest contribution to the formation of the level of pollution in the cold period of the year is made by suspended substances, iron and manganese compounds in concentrations exceeding the maximum permissible concentration. The concentration of impurities depends on the distance from large industrial objects, automobile and railway objects, sanitary and technical condition and cleaning regime of the territory. The courtyard territories of Smolensk and Vyazma are the cleanest. The largest part of snow pollution is provided by the thermoelectric power stations and transport. Samples taken near car parks, railway tracks and near the thermoelectric power stations were the most unfavorable

    Evolutionary Relationships Between the Laccase Genes of Polyporales: Orthology-Based Classification of Laccase Isozymes and Functional Insight From Trametes hirsuta

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    Laccase is one of the oldest known and intensively studied fungal enzymes capable of oxidizing recalcitrant lignin-resembling phenolic compounds. It is currently well established that fungal genomes almost always contain several non-allelic copies of laccase genes (laccase multigene families); nevertheless, many aspects of laccase multigenicity, for example, their precise biological functions or evolutionary relationships, are mostly unknown. Here, we present a detailed evolutionary analysis of the sensu stricto laccase genes (CAZy – AA1_1) from fungi of the Polyporales order. The conducted analysis provides a better understanding of the Polyporales laccase multigenicity and allows for the systemization of the individual features of different laccase isozymes. In addition, we provide a comparison of the biochemical and catalytic properties of the four laccase isozymes from Trametes hirsuta and suggest their functional diversification within the multigene family

    Martian dust storm impact on atmospheric H<sub>2</sub>O and D/H observed by ExoMars Trace Gas Orbiter

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    Global dust storms on Mars are rare but can affect the Martian atmosphere for several months. They can cause changes in atmospheric dynamics and inflation of the atmosphere, primarily owing to solar heating of the dust. In turn, changes in atmospheric dynamics can affect the distribution of atmospheric water vapour, with potential implications for the atmospheric photochemistry and climate on Mars. Recent observations of the water vapour abundance in the Martian atmosphere during dust storm conditions revealed a high-altitude increase in atmospheric water vapour that was more pronounced at high northern latitudes, as well as a decrease in the water column at low latitudes. Here we present concurrent, high-resolution measurements of dust, water and semiheavy water (HDO) at the onset of a global dust storm, obtained by the NOMAD and ACS instruments onboard the ExoMars Trace Gas Orbiter. We report the vertical distribution of the HDO/H O ratio (D/H) from the planetary boundary layer up to an altitude of 80 kilometres. Our findings suggest that before the onset of the dust storm, HDO abundances were reduced to levels below detectability at altitudes above 40 kilometres. This decrease in HDO coincided with the presence of water-ice clouds. During the storm, an increase in the abundance of H2O and HDO was observed at altitudes between 40 and 80 kilometres. We propose that these increased abundances may be the result of warmer temperatures during the dust storm causing stronger atmospheric circulation and preventing ice cloud formation, which may confine water vapour to lower altitudes through gravitational fall and subsequent sublimation of ice crystals. The observed changes in H2O and HDO abundance occurred within a few days during the development of the dust storm, suggesting a fast impact of dust storms on the Martian atmosphere

    Genomic analyses inform on migration events during the peopling of Eurasia.

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    High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, the availability of high-resolution genomic data has led to the development of new methodologies for inferring population history and refuelled the debate on the mutation rate in humans. Here we present the Estonian Biocentre Human Genome Diversity Panel (EGDP), a dataset of 483 high-coverage human genomes from 148 populations worldwide, including 379 new genomes from 125 populations, which we group into diversity and selection sets. We analyse this dataset to refine estimates of continent-wide patterns of heterozygosity, long- and short-distance gene flow, archaic admixture, and changes in effective population size through time as well as for signals of positive or balancing selection. We find a genetic signature in present-day Papuans that suggests that at least 2% of their genome originates from an early and largely extinct expansion of anatomically modern humans (AMHs) out of Africa. Together with evidence from the western Asian fossil record, and admixture between AMHs and Neanderthals predating the main Eurasian expansion, our results contribute to the mounting evidence for the presence of AMHs out of Africa earlier than 75,000 years ago.Support was provided by: Estonian Research Infrastructure Roadmap grant no 3.2.0304.11-0312; Australian Research Council Discovery grants (DP110102635 and DP140101405) (D.M.L., M.W. and E.W.); Danish National Research Foundation; the Lundbeck Foundation and KU2016 (E.W.); ERC Starting Investigator grant (FP7 - 261213) (T.K.); Estonian Research Council grant PUT766 (G.C. and M.K.); EU European Regional Development Fund through the Centre of Excellence in Genomics to Estonian Biocentre (R.V.; M.Me. and A.Me.), and Centre of Excellence for Genomics and Translational Medicine Project No. 2014-2020.4.01.15-0012 to EGC of UT (A.Me.) and EBC (M.Me.); Estonian Institutional Research grant IUT24-1 (L.S., M.J., A.K., B.Y., K.T., C.B.M., Le.S., H.Sa., S.L., D.M.B., E.M., R.V., G.H., M.K., G.C., T.K. and M.Me.) and IUT20-60 (A.Me.); French Ministry of Foreign and European Affairs and French ANR grant number ANR-14-CE31-0013-01 (F.-X.R.); Gates Cambridge Trust Funding (E.J.); ICG SB RAS (No. VI.58.1.1) (D.V.L.); Leverhulme Programme grant no. RP2011-R-045 (A.B.M., P.G. and M.G.T.); Ministry of Education and Science of Russia; Project 6.656.2014/K (S.A.F.); NEFREX grant funded by the European Union (People Marie Curie Actions; International Research Staff Exchange Scheme; call FP7-PEOPLE-2012-IRSES-number 318979) (M.Me., G.H. and M.K.); NIH grants 5DP1ES022577 05, 1R01DK104339-01, and 1R01GM113657-01 (S.Tis.); Russian Foundation for Basic Research (grant N 14-06-00180a) (M.G.); Russian Foundation for Basic Research; grant 16-04-00890 (O.B. and E.B); Russian Science Foundation grant 14-14-00827 (O.B.); The Russian Foundation for Basic Research (14-04-00725-a), The Russian Humanitarian Scientific Foundation (13-11-02014) and the Program of the Basic Research of the RAS Presidium “Biological diversity” (E.K.K.); Wellcome Trust and Royal Society grant WT104125AIA & the Bristol Advanced Computing Research Centre (http://www.bris.ac.uk/acrc/) (D.J.L.); Wellcome Trust grant 098051 (Q.A.; C.T.-S. and Y.X.); Wellcome Trust Senior Research Fellowship grant 100719/Z/12/Z (M.G.T.); Young Explorers Grant from the National Geographic Society (8900-11) (C.A.E.); ERC Consolidator Grant 647787 ‘LocalAdaptatio’ (A.Ma.); Program of the RAS Presidium “Basic research for the development of the Russian Arctic” (B.M.); Russian Foundation for Basic Research grant 16-06-00303 (E.B.); a Rutherford Fellowship (RDF-10-MAU-001) from the Royal Society of New Zealand (M.P.C.)

    Family business: property disputes resolution

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    Within the framework of this article, the problem of dividing a family business by spouses when being in divorce is considered. The paper presents possible options for dividing a family business based on judicial practice. The work covers some features of divorce if a spouse has a share in a limited liability company. The authors also note some distinctive features of the distribution of jointly acquired property, if one of the spouses has the status of an individual entrepreneur. And some nuances are also considered in the division of property in the event of the liquidation of a peasant (farm) economy. Court decisions on these issues are analyzed and reflected in the study
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