Оптимизация процессов легирования силумина ионно-электронно-плазменным методом

The surface morphology, chemical composition, microstructure, nanohardness, and tribological properties of a film silumin on aluminum were investigated. The film (Al-25% Si) / substrate (Al-12% Si) has modificated by ion-electron-plasma method. The wear resistance and hardness of a slight increase in 1.3 times

Регулируемый электропривод конвейера Распадской обогатительной фабрики

Цель работы – разработка и исследование регулируемого электропривода ленточного конвейера. Произведен расчет конвейера и выбор основного электрооборудования, построены электромеханические и механические характеристики асинхронного электродвигателя. Построены переходные процессы для различных режимов работы.The work purpose – development and research of the adjustable electric drive of the tape conveyor. Calculation of the conveyor and the choice of the capital electric equipment is made, electromechanical and mechanical characteristics of the asynchronous electric motor are constructed. Transition processes for various operating modes are constructed

Проектирование бизнес-модели спортивного квест-рума «SportQuest»

Цель данной выпускной квалификационной работы – разработка бизнес-модели стартап-проекта по реализации спортивно-развлекательных квестов для населения города Томска. Задачи, которые поставлены для достижения цели: – Проанализировать рынок квест-румов и отдельно спортивных квест-румов в мире, России и городе Томске; – Охарактеризовать бизнес-идею спортивного квест-рума и каждый из видов квеста в стартап-проекте – Построить бизнес-модель стартап-проекта и произвести расчёт показателей эффективности реализации проекта и определить его перспективность в реализации. Объект исследования – спортивный квест-рум в городе Томске. Предмет исследования – бизнес-модель спортивного квест-рума.The purpose of this final qualification work is to develop a business model for a startup project to implement sports and entertainment quests for the population of the city of Tomsk. Tasks that are set to achieve the goal: - Analyze the market of quest rooms and sports quest rooms separately in the world, Russia and the city of Tomsk; - Describe the business idea of the sports quest room and each of the types of quests in the startup project -Build a business model of the startup project and calculate the performance indicators of the project and determine its prospects for implementation. The object of the study is a sports quest room in the city of Tomsk. The subject of the research is the business model of a sports quest room

Feasibility of Prehospital Teleconsultation in Acute Stroke – A Pilot Study in Clinical Routine

BACKGROUND: Inter-hospital teleconsultation improves stroke care. To transfer this concept into the emergency medical service (EMS), the feasibility and effects of prehospital teleconsultation were investigated. METHODOLOGY/PRINCIPAL FINDINGS: Teleconsultation enabling audio communication, real-time video streaming, vital data and still picture transmission was conducted between an ambulance and a teleconsultation center. Pre-notification of the hospital was carried out with a 14-item stroke history checklist via e-mail-to-fax. Beside technical assessments possible influences on prehospital and initial in-hospital time intervals, prehospital diagnostic accuracy and the transfer of stroke specific data were investigated by comparing telemedically assisted prehospital care (telemedicine group) with local regular EMS care (control group). All prehospital stroke patients over a 5-month period were included during weekdays (7.30 a.m.-4.00 p.m.). In 3 of 18 missions partial dropouts of the system occurred; neurological co-evaluation via video transmission was conducted in 12 cases. The stroke checklist was transmitted in 14 cases (78%). Telemedicine group (n = 18) vs. control group (n = 47): Prehospital time intervals were comparable, but in both groups the door to brain imaging times were longer than recommended (median 59.5 vs. 57.5 min, p = 0.6447). The prehospital stroke diagnosis was confirmed in 61% vs. 67%, p = 0.8451. Medians of 14 (IQR 9) vs. 5 (IQR 2) stroke specific items were transferred in written form to the in-hospital setting, p<0.0001. In 3 of 10 vs. 5 of 27 patients with cerebral ischemia thrombolytics were administered, p = 0.655. CONCLUSIONS: Teleconsultation was feasible but technical performance and reliability have to be improved. The approach led to better stroke specific information; however, a superiority over regular EMS care was not found and in-hospital time intervals were unacceptably long in both groups. The feasibility of prehospital tele-stroke consultation has future potential to improve emergency care especially when no highly trained personnel are on-scene. TRIAL REGISTRATION: International Standard Randomised Controlled Trial Number Register (ISRCTN) ISRCTN83270177

Veränderung der Hämodynamik durch die Kombinationsnarkose aus Xenon und Isofluran im Vergleich zu der aus Xenon und Sevofluran an Schweinen

Measurements to the described hemodynamic parameters in mono-anesthesia with isoflurane or sevoflurane were taken as baseline values. Therefore the volatile anesthetics were administered at 1.0, 1.3 and 1.6 MAC. After that measurements together with xenon and one of the volatiles were performed. Xenon was delivered at increasing levels (15%, 30%, 40%, 50% and 65%) and each xenon concentration was combined with the volatiles at 1.0, 1.3, 1.6 MAC in a stepwise design. The parameters heart rate (HR), mean arterial pressure (MAP), cardiac output (CO) and systemic vascular resistence (TPR) were examined due to significant changes by administering different combinations of xenon together with isoflurane or sevoflurane. As a result the parameters are significantly changed only at high levels of xenon. In our study heart rate was decreased by using increased concentrations of both volatile anesthetics in mono-anesthesia due to a higher level of anesthesia. We suggest a “time-effect” because each pig in both groups shows continuously increasing values for heart rate according to the very long duration of the examination. The other parameters show no “time-effect”. The combination of xenon with isoflurane shows a significant increase of CO of 18% at 1.3 MAC and about 23.3 % at 1.6 MAC in 65% xenon. With use of sevoflurane increasing levels of CO are seen at first with 50 % xenon. They are about 25.2 % at 1.3 MAC and 34.6% at 1.6 MAC. There is a continuous increase in CO when using 1.6 MAC sevoflurane with each xenon concentration. The study shows significant increase in MAP when using isoflurane at 1.3 and 1.6 MAC together with all different xenon concentrations. When using sevoflurane we see this effect at 1.6 MAC. The study examined no significant alterations in TPR in mono-anesthesia. When using the combination with xenon the results were not uniform. In conclusion the combination of xenon together with isoflurane or sevoflurane can influence the hemodynamic situation in a positive matter when xenon is administered in a high concentration. In this study this effect can be seen for both volatile anesthetics when xenon is used at a concentration of 65%. There is an advantage for sevoflurane because the effect is also seen when xenon is administered only at 50%. In a matter of balanced anesthesia the combination of xenon with volatile anesthetics might stabilizise the hemodynamic situation by reducing volatiles MAC. Xenon itself has no adverse side effects. This form of anesthesia is favorable for patients with reduced cardiovascular compliance because they need a very high grade of cardiovascular stability and a high concentration of inspired oxygen

Veränderung der Hämodynamik durch die Kombinationsnarkose aus Xenon und Isofluran im Vergleich zu der aus Xenon und Sevofluran an Schweinen

Measurements to the described hemodynamic parameters in mono-anesthesia with isoflurane or sevoflurane were taken as baseline values. Therefore the volatile anesthetics were administered at 1.0, 1.3 and 1.6 MAC. After that measurements together with xenon and one of the volatiles were performed. Xenon was delivered at increasing levels (15%, 30%, 40%, 50% and 65%) and each xenon concentration was combined with the volatiles at 1.0, 1.3, 1.6 MAC in a stepwise design. The parameters heart rate (HR), mean arterial pressure (MAP), cardiac output (CO) and systemic vascular resistence (TPR) were examined due to significant changes by administering different combinations of xenon together with isoflurane or sevoflurane. As a result the parameters are significantly changed only at high levels of xenon. In our study heart rate was decreased by using increased concentrations of both volatile anesthetics in mono-anesthesia due to a higher level of anesthesia. We suggest a “time-effect” because each pig in both groups shows continuously increasing values for heart rate according to the very long duration of the examination. The other parameters show no “time-effect”. The combination of xenon with isoflurane shows a significant increase of CO of 18% at 1.3 MAC and about 23.3 % at 1.6 MAC in 65% xenon. With use of sevoflurane increasing levels of CO are seen at first with 50 % xenon. They are about 25.2 % at 1.3 MAC and 34.6% at 1.6 MAC. There is a continuous increase in CO when using 1.6 MAC sevoflurane with each xenon concentration. The study shows significant increase in MAP when using isoflurane at 1.3 and 1.6 MAC together with all different xenon concentrations. When using sevoflurane we see this effect at 1.6 MAC. The study examined no significant alterations in TPR in mono-anesthesia. When using the combination with xenon the results were not uniform. In conclusion the combination of xenon together with isoflurane or sevoflurane can influence the hemodynamic situation in a positive matter when xenon is administered in a high concentration. In this study this effect can be seen for both volatile anesthetics when xenon is used at a concentration of 65%. There is an advantage for sevoflurane because the effect is also seen when xenon is administered only at 50%. In a matter of balanced anesthesia the combination of xenon with volatile anesthetics might stabilizise the hemodynamic situation by reducing volatiles MAC. Xenon itself has no adverse side effects. This form of anesthesia is favorable for patients with reduced cardiovascular compliance because they need a very high grade of cardiovascular stability and a high concentration of inspired oxygen