Restaging role of 18F-FDG-PET/CT in a patient with a Malignant Peripheral Nerve Sheath Tumor (MPNST) caused by neurofibromatosis – case report

Malignant Peripheral Nerve Sheath Tumors (MPNST) are a malignant disease that originates in the cells that cover and protect the peripheral nerves. They are a rare disease, accounting for 6% of soft tissue sarcomas. We present a patient with a malignant peripheral nerve sheath tumor on the left brachium with neurofibromatosis. The patient underwent whole body PET/CT for restaging after total extirpation of a tumor formation originated from n. musculocutaneous in 09.2017, an excision of a recurrent tumor formation in the proximal half of the brachium invading into m. biceps brachii in 12.2017, a performed MRI in 02.2018 - with data for multiple MPSNT in the area between the two previous operations - and subsequent definitive radiotherapy (boost) in the area of the tumor formation and 6 cycles of chemotherapy with Epirubicin. After restaging PET/CT scan of the whole body was performed, progression of the disease was defined - increased in size and activity subpleural lesion in the lower lobe of the right lung

Monitoring the effect of therapy on a patient with a neuroendocrine tumor of the pancreas with PET/CT, 68Ga-DOTATATE - case report

Neuroendocrine tumors (NET) are a rare diagnosis, often without symptoms or mimicking other different symptoms. Тhey are a heterogeneous group of tumors derived from neuroendocrine cells, most commonly of the gastrointestinal tract, but may originate also from other organs including the pancreas, lungs, ovaries, thyroid, pituitary, and adrenal glands (3). Due to the difficult diagnosis, NET‘s are detected at a late stage in their development, often already locally advanced or metastasized. PET/CT with 68Gallium DOTATATE proved to be an effective imaging method not only for the primary diagnosis of NET and subsequent therapeutic behavior, but also for evaluating the effect of the treatment. (1) We present a case of a positive PET/CT scan, performed with Ga-68 DOTATATE in the topical location of the tail of the pancreas after therapy with Sandostain lar

Silvicultural Efficiency of the Thinning Efficiency of Pinus sylvestris L. Plantation in the Dry Subzone of Northern Kazakhstan Steppes

Aim of study: Thinning efficiency after 18 years of cutting at the Scots pine (Pinus sylvestris L.) plantations, in the subzone of the dry grass steppe, were examined. Area of study: On 45-year-old Scots pine plantations on the territory of the state enterprise ZhasylAimak in Nur-Sultan city in the Northern Kazakhstan. Material and methods: The plantations were established by high density planting (13,300 seedlings/ha) of 2-year old seedlings. The planting was carried out on forest-suitable soils. To assess the silvicultural efficiency of the thinning in the plantation, the coefficient of growth tension or a complex estimated figure (CEF) was used. Main results: The research confirm that Scots pine plantations can be established in the subzone of dry fescue feather-grass steppe (Festuca valesiaca-Stipetum capillatae Sillinger 1930). The maximum silvicultural effect of thinning was achieved with three steps. In the 1st step of the thinning of the forest, 1015 years old trees are cut down. Trees with over-developed crown are also cut down. The 2nd step is made in 25-30 years with thinning intensity of 25% by stock. The 3rd step is made in 40-50 years in a uniform way. Highlights: In the harsh climatic conditions of Northern Kazakhstan steppe, deciduous trees and shrubs begin to age and die much earlier than the long-lived Scots pine