Activities of Irish psychiatric services 2002 / Antoinette Daly, Dermot Walsh

HRB / 200

Mental illness in Ireland 1750 - 2002: reflections on the rise and fall of institutional care / Dermot Walsh and Antoinette Daly

HRB / 200

Activities of Irish psychiatric services 2003 / by Antoinette Daly...[et al].

HRB / 200

Activities of Irish psychiatric units and hospitals 2018.

There were 17,000 admissions to Irish psychiatric hospitals and units during 2018 according to the latest figures from the Health Research Board (HRB). This represents an increase of 257 from 2017. Depression, schizophrenia, mania, neurosis and alcoholic disorders account for over two-thirds of all admissions

Irish psychiatric units and hospitals census 2016: main findings.

This report presents findings from the ninth national psychiatric census of patients in psychiatric units and hospitals, the latest in a series of censuses first carried out in 1963. The census is a count of all patients resident in psychiatric units and hospitals operating within the provisions of the Mental Health Act 2001, (Government of Ireland, 2001), at midnight on 31 March 2016. Data for this report are based on residents in 64 units and hospitals on the Register of Approved Centres under the Mental Health Act 2001, including child and adolescent units. Eighty-four per cent of those with a diagnosis of intellectual disability had been in hospital for five years or more on census night. In contrast, 28% of those with schizophrenia, 19% of those with organic mental disorders, 19% of those with alcoholic disorders, 7% of those with depressive disorders and 12% of those with mania had been in hospital for five years or more on census night

Feasibility, acceptability, and safety of the Recapture Life videoconferencing intervention for adolescent and young adult cancer survivors

© 2018 John Wiley & Sons, Ltd. Objective: Online psychological therapies provide a way to connect adolescent and young adult (AYA) cancer survivors to evidence-based support. We aimed to establish the feasibility, acceptability, and safety of Recapture life, a six-session group-based online cognitive-behavioural intervention, led by a facilitator, for AYAs in the early post-treatment period. Methods: A randomised-controlled trial compared Recapture Life to an online peer-support group control and a waitlist control. Participants could nominate a support person. Acceptability was assessed using study opt-in and retention rates, participant-reported benefits/burdens of participation, and group facilitator burden. We also assessed the feasibility (eg, frequency/impact of technological difficulties) and psychological safety (ie, occurrence of clinically concerning distress) of the program. Results: Sixty-one participants took part (45 AYAs, 51.1% female; 19 support people). The opt-in rate was 30%, the enrolment rate was 87%, and 75% of participants took part in ≥5/6 sessions. AYAs reported high benefit and low burden of participation. Overall, 95 online group sessions were conducted; few required rescheduling by group facilitators (3%), but many took place outside of office hours (~90 hours). It took 40 days on average to create online groups, but established weekly sessions commenced quickly (M = 4.0 minutes). Technological difficulties were common but had a low impact on intervention delivery. Although 54% of AYAs returned a clinically concerning distress screen at some point, none reflected acute mental health risks. Conclusions: The data largely indicate that Recapture Life is an acceptable, feasible, and safe model of evidence-based psychological support for AYAs during early survivorship, which nevertheless experienced common challenges in online/AYA intervention delivery

Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel

To date, most BC GWASs have been performed Background Polygenic risk score (PRS), calculated in individuals of European (EUR) ancestry, and based on genome-wide association studies (GWASs), the generalisation of EUR-based PRS to other can improve breast cancer (BC) risk assessment. populations is a major challenge. In this study, we examined the performance of EUR-based BC PRS models in Ashkenazi Jewish (AJ) women. Methods We generated PRSs based on data on EUR women from the Breast Cancer Association Consortium (BCAC). We tested the performance of the PRSs in a cohort of 2161 AJ women from Israel (1437 cases and 724 controls) from BCAC (BCAC cohort from Israel (BCAC-IL)). In addition, we tested the performance of these EUR-based BC PRSs, as well as the established 313-SNP EUR BC PRS, in an independent cohort of 181 AJ women from Hadassah Medical Center (HMC) in Israel. Results In the BCAC-IL cohort, the highest OR per 1 SD was 1.56 (±0.09). The OR for AJ women at the top 10% of the PRS distribution compared with the middle quintile was 2.10 (±0.24). In the HMC cohort, the OR per 1 SD of the EUR-based PRS that performed best in the BCAC-IL cohort was 1.58±0.27. The OR per 1 SD of the commonly used 313-SNP BC PRS was 1.64 (±0.28). Conclusions Extant EUR GWAS data can be used for generating PRSs that identify AJ women with markedly elevated risk of BC and therefore hold promise for improving BC risk assessment in AJ women.</p