13 research outputs found

    A Cylinder of Nebuchadnezzar II from Uruk in the Cindy and David Sofer Collection displayed in the Bible Lands Museum Jerusalem

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    A three-column clay cylinder on display at the Bible Lands Museum (Jerusalem) and inscribed with an Akkadian inscription records Nebuchadnezzar II's (r. 604–562 BCE) reconstruction of Eanna (whose Sumerian name means "House of Heaven"), the temple of the goddess Ishtar at Uruk (modern Warka). Although this Neo-Babylonian king's rebuilding of Eanna has been known since the mid-nineteenth century, there has been little textual and archaeological evidence from Uruk itself to support Nebuchadnezzar's claims. This is the first positively-identified foundation document of this NeoBabylonian king to have come from Ishtar's most important temple in Babylonia. The cylinder's production was connected to the return of that goddess' statue to her beloved city during the reign of Nebuchadnezzar II

    Nabuchodonosor au Liban : les inscriptions de Brisa dans leur contexte historique

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    Nabuchodonosor II fut un roi charismatique et ses réalisations politiques et militaires ont transformé Babylone en une puissance mondiale. Sous son long règne (605-562 avant J.-C.), Babylone atteignit son extension territoriale maximale en annexant de vastes zones qui se trouvaient précédemment sous contrôle assyrien et en réduisant l'influence égyptienne en Syrie et au Levant (Carte). Régions et villes sous contrôle de l'Empire néo-babylonien. Suite à ses campagnes militaires, les matières ..

    Nabuchodonosor au Liban : les inscriptions de Brisa dans leur contexte historique

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    Nabuchodonosor II fut un roi charismatique et ses réalisations politiques et militaires ont transformé Babylone en une puissance mondiale. Sous son long règne (605-562 avant J.-C.), Babylone atteignit son extension territoriale maximale en annexant de vastes zones qui se trouvaient précédemment sous contrôle assyrien et en réduisant l'influence égyptienne en Syrie et au Levant (Carte). Régions et villes sous contrôle de l'Empire néo-babylonien. Suite à ses campagnes militaires, les matières ..

    Sources at the End of the Cuneiform Era

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    The aim of this article is to discuss several groups of sources which are of special interest regarding the question of Mesopotamian identities after 539 BCE, towards the end of the use of cuneiform writing. In this late period, several languages and scripts were in use in Mesopotamia; therefore, groups of Akkadian, Aramaic, Greek, and Sumerian texts are discussed. The scripts used are Aramaic letters, cuneiform, and the Greek alphabet. A scholar who is interested in late Mesopotamian identities needs to take all these documents into account. This article aims at giving a brief overview on available textual material and where to find it. The topics of these texts vary from administrative documents to highly literary texts. The authors discuss Aramaic inscriptions, legal and administrative cuneiform texts, the astronomical diaries, the Seleucid Uruk scholarly texts, the late Babylonian priestly literature, Emesal cult-songs from the Hellenistic period, the Graeco-Babyloniaca (clay tablets containing cuneiform and Greek), and finally Greek inscriptions from Mesopotamia.Peer reviewe

    Measurements of the pp -> ZZ production cross section and the Z -> 4l branching fraction, and constraints on anomalous triple gauge couplings at root s=13TeV

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    Correction: DOI:10.1140/epjc/s10052-018-5769-1Four-lepton production in proton-proton collisions, pp -> (Z/gamma*)(Z/gamma*) -> 4l, where l = e or mu, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 35.9 fb(-1). The ZZ production cross section, sigma(pp -> ZZ) = 17.2 +/- 0.5 (stat) +/- 0.7 (syst) +/- 0.4 (theo) +/- 0.4 (lumi) pb, measured using events with two opposite-sign, same-flavor lepton pairs produced in the mass region 60 4l) = 4.83(-0.22)(+0.23) (stat)(-0.29)(+0.32) (syst) +/- 0.08 (theo) +/- 0.12(lumi) x 10(-6) for events with a four-lepton invariant mass in the range 80 4GeV for all opposite-sign, same-flavor lepton pairs. The results agree with standard model predictions. The invariant mass distribution of the four-lepton system is used to set limits on anomalous ZZZ and ZZ. couplings at 95% confidence level: -0.0012 <f(4)(Z) <0.0010, -0.0010 <f(5)(Z) <0.0013, -0.0012 <f(4)(gamma) <0.0013, -0.0012 <f(5)(gamma) <0.0013.Peer reviewe

    Tapering Canakinumab Monotherapy in Patients with Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results from an Open\u2010label, Randomized Phase IIIb/IV Study

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    Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis

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    Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

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    Background Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates

    Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

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    International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
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