230 research outputs found
The Italian banking system: Facts and interpretations
The paper compares the essential features of the Italian banking system with those of the other large euro-area countries. The analysis focuses on banksâ size, ownership and competitiveness, their role in financing firms, the composition of their balance sheets and their degree of internationalization, profitability and terms for customers. Within this overall framework the paper examines the banking systemâs response to the financial crisis of 2007-09 and subsequent developments. The progress made in decades past is recalled and further necessary steps set out.Autore: Pozzolo, Alberto Franco; email: [email protected]
Bleeding risk evaluation in cerebral cavernous malformation, the role of medications, and hemorrhagic factors: a case-control study
Objective: Cerebral cavernous malformations (CCMs) are vascular lesions with an overall risk of rupture from 2% to 6% per year, which is associated with significant morbidity and mortality. The diagnostic incidence is increasing, so it is of paramount importance to stratify patients based on their risk of rupture. Data in the literature seem to suggest that specific medications, particularly antithrombotic and cardiovascular agents, are associated with a reduced risk of bleeding. However, the effect of the patient coagulative status on the cumulative bleeding risk remains unclear. The aim of this study was to assess the impact of different radiological, clinical, and pharmacological factors on the bleeding risk of CCMs and to assess the predictive power of an already validated scale for general bleeding risk, the HAS-BLED (hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile international normalized ratio, elderly, drugs/alcohol concomitantly). Method: This was a multicenter retrospective observational study. The authors collected imaging, clinical status, and therapy data on patients with bleeding and nonbleeding CCMs. Univariate analysis and subsequent multivariate logistic regression were performed between the considered variables and bleeding or nonbleeding status to identify potential independent predictors of bleeding. Results: The authors collected data on 257 patients (46.7% male, 25.3% with bleeding CCMs). Compared with patients with nonbleeding lesions, those with bleeding CCMs were younger, less frequently had hypertension, and less frequently required antiplatelet drugs and beta-blockers (all p < 0.05). Bleeding lesions, however, had significantly higher median volumes (1050 mm3 vs 523 mm3 , p < 0.001). On multivariate analyses, after adjusting for age, history of hypertension and diabetes, and use of antiplatelet drugs or beta-blockers, lesion volume â„ 300 mm3 was the only significant predictor of bleeding (adjusted OR 3.11, 95% CI 1.09-8.86). When the diagnostic accuracy of different volume thresholds was explored, volume â„ 300 mm3 showed a limited sensitivity (36.7%, 95% CI 24.6%-50.0%), but a high specificity 78.2% (95% CI 71.3%-84.2%), with an area under the curve of 0.57 (95% CI 0.51-0.64). Conclusions: This study supports previous findings that the CCM volume is the only factor influencing the bleeding risk. Antithrombotic agents and propranolol seem to have a protective role against the bleeding events. A high HAS-BLED score was not associated with an increased bleeding risk. Further studies are needed to confirm these results
New Insights of Historical Mortars Beyond Pompei: The Example of Villa del Pezzolo, Sorrento Peninsula
The topic of this study is the archaeometric characterization of mortars from Villa del Pezzolo, a Roman Villa located in Seiano (Napoli-Campania, Italy), dated between the 1st century B.C. and the 3rd century A.D. Mortars were analyzed by means of a multi-analytical approach (polarized optical microscopy, X-ray powder diffraction, scanning electron microscopy and energy-dispersed spectrometry, thermal analyses and mercury intrusion porosimetry) according to existing recommendations. Analytical results evidenced the use of local geomaterials composed of sedimentary and volcanic aggregates in the mix design and confirmed the three distinct building phases identified by archaeologists. Volcanic tuff fragments, identified in the 1st building phase can be ascribed to Campanian Ignimbrite formation, widely cropping out in the Sorrento Peninsula, as confirmed by the presence of glassy shards, partially devitrified and replaced by authigenic feldspar, a typical feature of welded grey ignimbrite lithofacies (WGI). Volcanic aggregates in samples of the 2nd and 3rd building phases show, instead, the presence of leucite-bearing volcanic scoriae and garnet crystal fragments related to Somma-Vesuvius products. Study of these mortars allowed us to: (1) understand the production technologies; (2) highlight use of materials with hydraulic behavior, such as volcanic and fictile fragments; (3) confirm the three building phases from compositional features of mortars and (4) highlight the change over time of the volcanic aggregate for mortars mix-design
Biotic, mineralogical, petrographic, and geomorphological characterization of the Falerno-Domitio shoreline (Campania region, southern Italy), with implication for environmental health studies: preliminary results
We report the first results of an ongoing study related to the project FARO (i.e. the Italian âFund for original research projectsâ, granted by the UniversitĂ di Napoli Federico II and IMI bank partner). This research project aims to the enhancement of the physical and biotic features of the coastal landscape related to the Falerno-Domitio shoreline, located in the mid-north coast of the Campania region (southern Italy), from the Garigliano river and Torregaveta. In the national scenario, this area can be considered as a valuable ânatural laboratoryâ, for its wildlife (i.e. the Natural Reserve Foce Volturno, the Regional Park of Campi Flegrei, etc.), famous archaeological sites (i.e. Cuma excavations), and peculiar geological and volcanological characteristics (i.e. Phlegraean Fields). Unfortunately, it also suffers for a strong pollution and environmental degradation due to human activities. The research consists of a multidisciplinary analysis, mainly based on a bathymetric sensing, sampling of both the sea bottom sediments and the beach sands; it comprises: 1) integrated monitoring of the quality of environmental health through a biological study, 2) geomorphological and sedimentological analyses of the area and of the whole sample sets, with GIS data processing, 3) taxonomic and ecological analyses of selected benthic meiofauna assemblages, 4) mineralogy, petrography and geochemistry of beach sands along the shoreline, as well as of sea bottom samples. A complete sampling work of the beach sands, from the Garigliano estuary to the Cuma site, has been done, and the results of mineralogical, petrographic and chemical features, mainly in relation to major and trace elements data, as well as the granulometric curves, are presented. The ecologic and eco-toxicological studies are also carried out on selected samples, revealing the structure of meiofauna (benthic foraminifers and ostracods) assemblages. Tests on the occurrence of the bio-indicator organism Artemia salina have also performed, showing a relatively low toxicity of the samples analysed up to now. Preliminary bathymetric data are also presented
Detection chain and electronic readout of the QUBIC instrument
The Q and U Bolometric Interferometer for Cosmology (QUBIC) Technical Demonstrator (TD) aiming to shows the feasibility of the combination of interferometry and bolometric detection. The electronic readout system is based on an array of 128 NbSi Transition Edge Sensors cooled at 350mK readout with 128 SQUIDs at 1K controlled and amplified by an Application Specific Integrated Circuit at 40K. This readout design allows a 128:1 Time Domain Multiplexing. We report the design and the performance of the detection chain in this paper. The technological demonstrator unwent a campaign of test in the lab. Evaluation of the QUBIC bolometers and readout electronics includes the measurement of I-V curves, time constant and the Noise Equivalent Power. Currently the mean Noise Equivalent Power is ~ 2 x 10â»ÂčⶠW/âHz
Detection chain and electronic readout of the QUBIC instrument
The Q and U Bolometric Interferometer for Cosmology (QUBIC) Technical Demonstrator (TD) aiming to shows the feasibility of the combination of interferometry and bolometric detection. The electronic readout system is based on an array of 128 NbSi Transition Edge Sensors cooled at 350mK readout with 128 SQUIDs at 1K controlled and amplified by an Application Specific Integrated Circuit at 40K. This readout design allows a 128:1 Time Domain Multiplexing. We report the design and the performance of the detection chain in this paper. The technological demonstrator unwent a campaign of test in the lab. Evaluation of the QUBIC bolometers and readout electronics includes the measurement of I-V curves, time constant and the Noise Equivalent Power. Currently the mean Noise Equivalent Power is ~ 2 x 10â»ÂčⶠW/âHz
A study of CP violation in B-+/- -> DK +/- and B-+/- -> D pi(+/-) decays with D -> (KSK +/-)-K-0 pi(-/+) final states
A first study of CP violation in the decay modes and , where labels a or meson and labels a or meson, is performed. The analysis uses the LHCb data set collected in collisions, corresponding to an integrated luminosity of 3 fb. The analysis is sensitive to the CP-violating CKM phase through seven observables: one charge asymmetry in each of the four modes and three ratios of the charge-integrated yields. The results are consistent with measurements of using other decay modes
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