Constraints on Baryon-Nonconserving Yukawa Couplings in a Supersymmetric Theory

The 1-loop evolution of couplings in the minimal supersymmetric standard model, extended to include baryon nonconserving $(B\!\!\!/)$ operators through explicit $R$-parity violation, is considered keeping only $B\!\!\!/$ superpotential terms involving the maximum possible number of third generation superfields. If all retained Yukawa couplings $Y_i$ are required to remain in the perturbative domain $(Y_i < 1)$ upto the scale of gauge group unification, upper bounds ensue on the magnitudes of the $B\!\!\!/$ coupling strengths at the supersymmetry breaking scale, independent of the model of unification. They turn out to be similar to the corresponding fixed point values reached from a wide range of $Y_i$ (including all $Y_i$ greater than unity) at the unification scale. The coupled evolution of the top and $B\!\!\!/$ Yukawa couplings results in a reduction of the fixed point value of the former.Comment: PRL-TH-94/8 and TIFR/TH/94-7, 15 pages, LaTe

Signals of neutralinos and charginos from gauge boson fusion at the CERN Large Hadron Collider

We point out that interesting signals of the non-strongly interacting sector of the supersymmetric standard model arise from the production of charginos and neutralinos via vector boson fusion (VBF) at the Large Hadron Collider (LHC). In particular, if R-parity is violated, the hadronically quiet signals of charginos and neutralinos through direct production get considerably suppressed. We show that in such cases, the VBF channel can be useful in identifying this sector through clean and background-free final states.Comment: 10 pages Latex, 8 figures, minor changes in text and few references added, to be published in Phys. Rev.

Like Sign Dilepton Signature for R-Parity Violating SUSY Search at the Tevatron Collider

The like sign dileptons provide the most promising signature for superparticle search in a large category of $R$-parity violating SUSY models. We estimate the like sign dilepton signals at the Tevatron collider, predicted by these models, over a wide region of the MSSM parameter space. One expects an unambiguous signal upto a gluino mass of $200 - 300$ GeV ($\geq 500$ GeV) with the present (proposed) accumulated luminosity of $\sim 0.1~(1)~{\rm fb}^{-1}$.Comment: 12 page LaTeX file; 5 figures available upon request from the autho

Recursive Calculation of One-Loop QCD Integral Coefficients

We present a new procedure using on-shell recursion to determine coefficients of integral functions appearing in one-loop scattering amplitudes of gauge theories, including QCD. With this procedure, coefficients of integrals, including bubbles and triangles, can be determined without resorting to integration. We give criteria for avoiding spurious singularities and boundary terms that would invalidate the recursion. As an example where the criteria are satisfied, we obtain all cut-constructible contributions to the one-loop n-gluon scattering amplitude, A_n^{oneloop}(...--+++...), with split-helicity from an N=1 chiral multiplet and from a complex scalar. Using the supersymmetric decomposition, these are ingredients in the construction of QCD amplitudes with the same helicities. This method requires prior knowledge of amplitudes with sufficiently large numbers of legs as input. In many cases, these are already known in compact forms from the unitarity method.Comment: 36 pages; v2 clarification added and typos fixed, v3 typos fixe

Aids-related plasmablastic lymphoma of the oral cavity associated with an IgH/MYC translocation–treatment with autologous stem-cell transplantation in a patient with severe haemophilia-A

Plasmablastic lymphoma is an AIDS related lymphoma that continues to have a poor prognosis despite significant advances in the management of HIV and lymphoproliferative diseases. In part this has been due to limited insights into the biology of this disease and the molecular mechanisms of oncogenesis. To date molecular abnormalities have not been described in plasmablastic lymphoma, and its aggressive clinical behaviour has been difficult to understand. We describe the first reported cytogenetic abnormality in plasmablastic lymphoma, an IgH/MYC translocation. It is also the first description of autologous stem cell transplantation in a patient with severe haemophilia A

A study of single sneutrino production in association with fermion pairs at polarised photon colliders

We investigate single sneutrino production in the context of R-parity-violating Supersymmetry at future $\gamma\gamma$ linear colliders. The sneutrino is produced in association with fermion pairs and it is shown that its decays into two further fermions will lead to a clean signal. We also discuss possible backgrounds and the effects of beam polarisation.Comment: 31 pages, LaTeX, 10 postscript figures. Title has been modified. Two new figures and one appendix added. Detailed SM background estimations were made. A new reference added. Version to appear in PR

Genomic landscape and actionable mutations of brain metastases derived from non–small cell lung cancer: A systematic review

Background Brain metastases derived from non–small cell lung cancer (NSCLC) represent a significant clinical problem. We aim to characterize the genomic landscape of brain metastases derived from NSCLC and assess clinical actionability. Methods We searched Embase, MEDLINE, Web of Science, and BIOSIS from inception to 18/19 May 2022. We extracted information on patient demographics, smoking status, genomic data, matched primary NSCLC, and programmed cell death ligand 1 expression. Results We found 72 included papers and data on 2346 patients. The most frequently mutated genes from our data were EGFR (n = 559), TP53 (n = 331), KRAS (n = 328), CDKN2A (n = 97), and STK11 (n = 72). Common missense mutations included EGFR L858R (n = 80) and KRAS G12C (n = 17). Brain metastases of ever versus never smokers had differing missense mutations in TP53 and EGFR, except for L858R and T790M in EGFR, which were seen in both subgroups. Of the top 10 frequently mutated genes that had primary NSCLC data, we found 37% of the specific mutations assessed to be discordant between the primary NSCLC and brain metastases. Conclusions To our knowledge, this is the first systematic review to describe the genomic landscape of brain metastases derived from NSCLC. These results provide a comprehensive outline of frequently mutated genes and missense mutations that could be clinically actionable. These data also provide evidence of differing genomic landscapes between ever versus never smokers and primary NSCLC compared to the BM. This information could have important consequences for the selection and development of targeted drugs for these patients

Higgs Boson Decay into Hadronic Jets

The remarkable agreement of electroweak data with standard model (SM) predictions motivates the study of extensions of the SM in which the Higgs boson is light and couples in a standard way to the weak gauge bosons. Postulated new light particles should have small couplings to the gauge bosons. Within this context it is natural to assume that the branching fractions of the light SM-like Higgs boson mimic those in the standard model. This assumption may be unwarranted, however, if there are non-standard light particles coupled weakly to the gauge bosons but strongly to the Higgs field. In particular, the Higgs boson may effectively decay into hadronic jets, possibly without important bottom or charm flavor content. As an example, we present a simple extension of the SM, in which the predominant decay of the Higgs boson occurs into a pair of light bottom squarks that, in turn, manifest themselves as hadronic jets. Discovery of the Higgs boson remains possible at an electron-positron linear collider, but prospects at hadron colliders are diminished substantially.Comment: 30 pages, 7 figure

Search for Global Dipole Enhancements in the HiRes-I Monocular Data above 10^{18.5} eV

Several proposed source models for Ultra-High Energy Cosmic Rays (UHECRs) consist of dipole distributions oriented towards major astrophysical landmarks such as the galactic center, M87, or Centaurus A. We use a comparison between real data and simulated data to show that the HiRes-I monocular data for energies above 10^{18.5} eV is, in fact, consistent with an isotropic source model. We then explore methods to quantify our sensitivity to dipole source models oriented towards the Galactic Center, M87, and Centaurus A.Comment: 17 pages, 31 figure

Analysis of the vector form factors fKπ+(Q2)f^+_{K\pi}(Q^2) and fKπ−(Q2)f^-_{K\pi}(Q^2) with light-cone QCD sum rules

In this article, we calculate the vector form factors $f^+_{K\pi}(Q^2)$ and $f^-_{K\pi}(Q^2)$ within the framework of the light-cone QCD sum rules approach. The numerical values of the $f^+_{K\pi}(Q^2)$ are compatible with the existing theoretical calculations, the central value of the $f^+_{K\pi}(0)$, $f^+_{K\pi}(0)=0.97$, is in excellent agreement with the values from the chiral perturbation theory and lattice QCD. The values of the $|f^-_{K\pi}(0)|$ are very large comparing with the theoretical calculations and experimental data, and can not give any reliable predictions. At large momentum transfers with $Q^2> 5GeV^2$, the form factors $f^+_{K\pi}(Q^2)$ and $|f^-_{K\pi}(Q^2)|$ can either take up the asymptotic behavior of $\frac{1}{Q^2}$ or decrease more quickly than $\frac{1}{Q^2}$, more experimental data are needed to select the ideal sum rules.Comment: 22 pages, 16 figures, revised version, to appear in Eur. Phys. J.