A predição do crescimento intrauterino restrito a partir do doppler das artérias uterinas no primeiro trimestre da gestação

Backgroud: Intrauterine growth restriction (IUGR) is obstetric complications at high risk of perinatal morbidity and mortality and long-term permanent damage. In this study, IUGR is defined by fetal weight below the 10th percentile for gestational age (GA). Objectives: To associate the value of the average PI of uterine (PIaUt) between 11-14 weeks of gestation, with the prediction of newborns with birth weight below the 10th percentile and 5 for gestational age and require interruption of pregnancy before 37 weeks. Methods: A retrospective, cross-sectional, observational study including 693 singleton pregnancies with evaluation of the PI of the uterine arteries in the first trimester from October 2010 to December 2013 in Maternidade Escola - UFRJ (ME-UFRJ). Outcomes were recorded in the medical records: infants with birth weight below the 10th percentile (IUGR10) and the 5th percentile (IUGR5); IUGR 10 with delivery before 37 weeks (IUGR 0.5 in all associations made, however, was not entirely satisfactory because there intersection PIaUt values in normal and pathological pregnancy, which reflects the low sensitivity of your individual use. However, the test is good for correctly classifying 80% to 90% of the sample from the PIaUt 2.4, with high specificity as 90% of normal pregnancies have value below 2.4. The benefit to be achieved with the early identification of risk pregnancies for the development of fetuses with IUGR is to establish clinical protocols to ensure the risk pregnancies, conducting proper fetal workup in the third trimester, to the clinical management appropriate and optimized perinatal outcomes. Conclusion: PIaUt in the first trimester of pregnancy was associated on a regular basis to predicting the IUGR.Introdução: O crescimento intrauterino restrito (CIR) constitui intercorrência obstétrica com risco elevado de morbimortalidade perinatal e de danos permanentes a longo prazo. Neste trabalho, define-se, por CIR, fetos com peso abaixo do percentil 10 para idade gestacional (IG). OBJETIVOS: Associar o valor do PI médio das uterinas (PImUt), entre 11-14 semanas de gestação, com a predição de recémnascidos com peso ao nascer abaixo do percentil 10 e 5 para a idade gestacional e que necessitam de interrupção da gestação antes de 37 semanas. Metodologia: estudo retrospectivo, transversal e observacional, incluindo 693 gestações únicas com avaliação do PI das artérias uterinas no primeiro trimestre no período de outubro de 2010 a dezembro de 2013 na Maternidade Escola - UFRJ (MEUFRJ). Os desfechos foram verificados nos prontuários médicos: RN com peso ao nascer abaixo do percentil 10 (CIR10) e do percentil 5 (CIR5); CIR 10 com interrupção da gestação antes de 37 semanas (CIR10 0,5 em todas associações feitas, porém, não foi totalmente satisfatório porque há interseção de valores do PImUt em gestantes normais e patológicas, que reflete na baixa sensibilidade do seu uso isolado. No entanto, o teste é bom para classificar corretamente 80% a 90% da amostra a partir do PImUt de 2,4, com alta especificidade já que 90% das gestações normais têm valor abaixo de 2,4. O benefício que deve ser alcançado com a identificação precoce de gestações de risco para o desenvolvimento de fetos com CIR é o estabelecimento de protocolos clínicos que garantam às gestações de risco, a realização de adequada propedêutica fetal no 3o trimestre, a fim de o manejo clinico seja adequado e os resultados perinatais otimizados. Conclusão: O PImUt no 1o trimestre da gestação associou-se de maneira regular na predição do CIR

AMPLIANDO OS SABERES EM SAÚDE - MÍDIAS SOCIAIS COMO FERRAMENTA DA EDUCAÇÃO EM SAÚDE PARA A COVID-19

A pandemia do novo Coronavírus (Sars-CoV-2), causador da COVID-19, gerou um impacto de grande proporção na vida das pessoas, com necessidade de mudanças de hábitos e necessidade de informações sobre a nova doença. Por outro lado, as mídias sociais configuram-se como importantes canais de informação, comunicação e criação de conteúdos. No último ano, observou-se que o número de pessoas que buscam se atualizar sobre a pandemia do novo coronavírus pelas redes sociais cresceu consideravelmente. Porém, a participação intensiva nas redes sociais pode gerar um excesso de informação ou, em muitos casos, desinformação sobre a pandemia. A exposição informações falsas ou descontextualizadas sobre a pandemia podem mudar as ações das pessoas, consequentemente, colocando as em perigo. Com isso, o Ampliando Saberes em Saúde usou a força das mídias sociais para promover conteúdos científicos educacionais sobre a COVID-19, com uma linguagem simplificada, acessível e confiável. Este projeto de extensão universitária criou páginas no Instagram e Facebook com conteúdo científicos digitais, postados três vezes na semana, direcionados à promoção do conhecimento e educação em saúde sobre a COVID-19. Ao longo do ano de 2020 e início de 2021 foram postados 116 conteúdos digitais, utilizando o formato de vídeos e folhetos. O número de seguidores das páginas cresceu ao longo deste período, bem como as interações com as publicações. Diante disto, o projeto alcançou o seu principal objetivo que é promover as medidas de saúde que auxiliam na contenção da propagação do vírus, bem como educar a população sobre a COVID-19, democratizando o conhecimento e reduzindo a rede de desinformação

Synthesis, characterization and biological activity of novel Cu(II) complexes of 6-methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehy de-4N-substituted thiosemicarbazones

Three new 6-methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehyde-thiosemicarbazones-N-4-substituted pro-ligands and their Cu(II) complexes (1, -NH2; 2, -NHMe; 3, -NHEt) have been prepared and characterized. In both the X-ray structures of 1 and 3, two crystallographically independent complex molecules were found that differ either in the nature of weakly metal-binding species (water in 1a and nitrate in 1b) or in the co-ligand (water in 3a and methanol in 3b). Electron Paramagnetic Resonance (EPR) measurements carried out on complexes 1 and 3 confirmed the presence of such different species in the solution. The electrochemical behavior of the pro-ligands and of the complexes was investigated, as well as their biological activity. Complexes 2 and 3 exhibited a high cytotoxicity against human tumor cells and 3D spheroids derived from solid tumors, related to the high cellular uptake. Complexes 2 and 3 also showed a high selectivity towards cancerous cell lines with respect to non-cancerous cell lines and were able to circumvent cisplatin resistance. Via the Transmission Electron Microscopy (TEM) imaging technique, preliminary insights into the biological activity of copper complexes were obtained

Avaliação biomecânica das atividades de corte de madeira semimecanizado na Amazônia.

O objetivo deste trabalho é realizar uma análise biomecânica das posturas adotadas pelos trabalhadores nas atividades de corte arbóreo em florestas naturais, no Estado do Pará. Para avaliar as posturas dos trabalhadores nas atividades de derrubada, traçamento e destocamento utilizaram-se os métodos OWAS, REBA e de Michigan. Pelo OWAS todas as posturas adotadas exigem medidas corretivas em um futuro próximo. Pelo REBA a atividade de derrubada apresentou situação mais crítica. Pelo modelo biomecânico as articulações dos cotovelos e dos ombros não apresentaram risco de lesão. A força de compressão do disco L5-S1 ultrapassou o valor recomendado na atividade de destocar

Da doença ao milagre: etnografia de soluções terapêuticas entre evangélicos na cidade de Boa Vista, Roraima

São várias as possibilidades de articulação entre doença, religião e cura. O artigo em questão constitui uma análise de narrativas sobre doença e cura pela religião, realizada a partir de abordagem etnográfica em 10 bairros de Boa Vista, Roraima, com indivíduos que afirmaram terem sido curados através de intervenção divina. Os resultados mostram que a doença não se reduz aos sintomas físicos universais da realidade empírica. Rituais mágicos de cura são, também, caminhos abertos à sua interpretação

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration

Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector

Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02  TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1  μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos⁡2Δϕ modulation for all ΣETPb ranges and particle pT

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector

This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}$and correspond to an integrated luminosity of$4.6\;{\rm f}{{{\rm b}}^{-1}}$. The measurement is performed by reconstructing the boosted W or Z bosons in single jets. The reconstructed jet mass is used to identify the W and Z bosons, and a jet substructure method based on energy cluster information in the jet centre-of-mass frame is used to suppress the large multi-jet background. The cross-section for events with a hadronically decaying W or Z boson, with transverse momentum${{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}$and pseudorapidity$|\eta |\lt 1.9$, is measured to be${{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques