Difficulties met by Unicamp students in the transition to remote learning

This paper conducts an exploratory analysis of data collected from a survey with Brazilian students at Universidade Estadual de Campinas (Unicamp) about the difficulties observed in the transition from in-person to remote learning due to the Covid-19 pandemic. We conducted bibliographic research and applied exploratory factor analysis (EFA) to responses from 1,776 students. Our goal was to obtain a model that explains most of the variance in the data. Upon analyzing the EFA results, two groups of difficulties stood out: those related to course planning and those related to access and the provision of adequate infrastructure for remote learning. These findings can contribute to higher education institutions’ institutional plans. Importantly, we are not inferring a prevalence of difficulties, but rather emphasizing that university stakeholders should actively analyze and explore these challenges

Drug allergy

Drug allergy encompasses a spectrum of immunologically-mediated hypersensitivity reactions with varying mechanisms and clinical presentations. This type of adverse drug reaction (ADR) not only affects patient quality of life, but may also lead to delayed treatment, unnecessary investigations, and even mortality. Given the myriad of symptoms associated with the condition, diagnosis is often challenging. Therefore, referral to an allergist experienced in the identification, diagnosis and management of drug allergy is recommended if a drug-induced allergic reaction is suspected. Diagnosis relies on a careful history and physical examination. In some instances, skin testing, graded challenges and induction of drug tolerance procedures may be required

The university contribution to sustainable development in Brazil: an analysis of the institutionalization of HIDS-Unicamp

This article aims to discuss the International Hub for Sustainable Development (HIDS), integrated into the University of Campinas (Unicamp/Brazil) and to the regional context of the city of Campinas, state of São Paulo, Brazil. We seek to present and analyze the experience of formulating and implementing HIDS, in view of its history of constitution, participating actors, structuring process, and its perspective of the concepts of sustainability and scientific and technological development. The HIDS concerns a partnership between 14 institutions, which correspond to legal categories such as public companies, higher education institutions, state authorities, social organizations, private law foundations, research, development and innovation institutions, multinationals companies, among others. In addition, it aims to contribute to the process of sustainable development, considering the production of knowledge and technologies through national and international cooperation, to mitigate and solve problem-situations in contemporary society. Methodologically, this article consists of bibliographic reviews and access to documents and information published on the institutional website of the researched experience. Considering that HIDS is a project still in the structuring and implementation phase, the focus of the analysis is on presenting the initiative’s formulation trajectory, its context and constitution process, as well as its alignment in relation to the main  mobilized topics. In addition, it is worth discussing which models of international experiences are cited in their constitution process and how these experiences impact the emergence and current structure of HIDS. Therefore, we aim to contribute to the reflection on innovative institutional initiatives, whose main mission is oriented to the promotion of transformative technologies and enterprises, integrated urban development, and sustainability.Este artigo tem como objetivo dissertar sobre o Hub Internacional para o Desenvolvimento Sustentável (HIDS), integrado à Universidade Estadual de Campinas (Unicamp/Brasil) e ao contexto regional do município de Campinas, estado de São Paulo, Brasil. Em outras palavras, busca-se apresentar e analisar a experiência de formulação e implementação do HIDS, tendo em vista seu histórico de constituição, atores participantes, estruturação e sua visão relativa aos conceitos de sustentabilidade e de desenvolvimento científico e tecnológico. O HIDS diz respeito a uma parceria realizada entre 14 instituições, que correspondem a categorias jurídicas como empresas públicas, instituições de ensino superior, autarquias estaduais, organizações sociais, fundações de direito privado, instituições de pesquisa, desenvolvimento e inovação, empresas multinacionais, entre outras. Além disso, possui como objetivo contribuir para o processo do desenvolvimento sustentável, considerando-se a produção de conhecimento e tecnologias por meio de cooperações nacionais e internacionais, de modo a mitigar e solucionar situações-problema da sociedade contemporânea. Metodologicamente, este artigo constitui-se a partir de revisões bibliográficas e acesso aos documentos e informações publicadas pelo site institucional da experiência pesquisada. Em razão do HIDS se constituir em um projeto ainda em fase de estruturação e implementação, o foco da análise está em apresentar a trajetória de formulação da iniciativa, seu contexto e processo de constituição, bem como seu alinhamento em relação às principais temáticas mobilizadas. Além disso, importa discutir quais modelos de experiências internacionais são citados em seu processo de constituição e de que forma tais experiências impactam o surgimento e estrutura atual do HIDS. Dessa maneira, este artigo visa contribuir para a reflexão em torno de iniciativas institucionais inovadoras, cuja missão principal esteja orientada para a promoção de tecnologias e empreendimentos transformadores, desenvolvimento urbano integrado e sustentabilidade

Diagnostic accuracy of the disturbed sleep pattern in patients with acute coronary syndrome

Objective: To clinically validate the nursing diagnosis, disturbed sleep pattern (00198), in patients with acute coronary syndrome. Data collection: A clinical validation study using the patient history, Visual Analog Sleep scale, and diagnostic inference. Accuracy techniques were performed. Synthesis of data: There were 75 patients: 76.00% were men, and 82.66% had a myocardial infarction. The defining characteristic, changes in sleep pattern, presented a sensitivity of 0.900 and specificity of 0.9714. Conclusion: Changes in sleep pattern was a predictor of the nursing diagnosis. Implications for practice: Results will contribute to the identification of sleep disturbances, by nurses, emphasizing the importance of improving sleep during hospitalization.312101108Objetivo: Validar clinicamente o Diagnóstico de Enfermagem Padrão de Sono Prejudicado (00198) em pacientes com Síndrome Coronariana Aguda. Métodos: Estudo de validação clínica, utilizando Histórico de Enfermagem, Escalas Visuais Análogas do Sono e inferência diagnóstica. Realizada medidas de acurácia. Resultados: 75 pacientes, 76,00% homens e 82,66% com Infarto do Miocárdio. A característica definidora Alteração do Padrão de Sono teve 0,900 de Sensibilidade e 0,9714 de Especificidade. Conclusões: Alteração do padrão de sono foi preditora do diagnóstico de enfermagem. Implicações para a prática: Contribuirá na identificação de distúrbios do sono, pelos enfermeiros, ressaltando a importância da melhoria do sono durante a internação

Inhaled Fluorescent Magnetic Nanoparticles Induced Extramedullary Hematopoiesis in the Spleen of Mice

Inhaled Fluorescent Magnetic Nanoparticles Induced Extramedullary Hematopoiesis in the Spleen of Mice: Jung-Taek KWON, et al. Laboratory of Toxicology, College of Veterinary Medicine, Seoul National University, Korea-Objectives: Nanomaterials are used in a wide variety of industrial materials such as semiconductors, magnetic resonance imaging, gene delivery carriers for gene therapy and many others; thus, human seems to be frequently exposed to them. Such diverse applications of nanoparticles elicit the need to identify the positive aspects of nanomaterials while avoiding the potential toxic effects. In this study, inhalation toxicity of manufactured nanomaterials using fluorescent magnetic nanoparticles (FMNPs) was assessed to address the issue of potential nanoparticle toxicity. Methods: Biological samples from a previous mouse FMNP exposure experiment were analyzed for potential FMNP toxicity. Mice inhaled FMNPs for 4 wk through a nose-only exposure chamber developed by our group for 4 wk and the potential toxicity of FMNPs was analyzed. Results: The nanoparticle distribution by scanning mobility particle sizer (SMPS) analysis showed that the mean values of number concentration (mass concentrations) in the nose-only exposure chamber were maintained at 4.89x10(5)/cm(3) (approximately 159.4 mu g/m(3)) for the low concentration and 9.34x10(5)/cm(3) (approximately 319.5 mu g/m(3)) for the high concentration, respectively. Inhalation of FMNPs caused a decrease of body weight and significant changes of white blood cells (WBCs) levels in whole blood. The FMNPs induced extramedullary hematopoiesis in the spleen without having a pulmonary effect. Conclusions: Our results support the proposition that extensive toxicity evaluation is needed for practical applications of anthropogenic nanomaterials and suggest that careful regulation of nanoparticle applications may be necessary to maintain a high quality of life as well as for facilitating the development of nanotechnology. (J Occup Health 2009; 51: 423-431)Y