2,966 research outputs found

    Extended skyrmion lattice scattering and long-time memory in the chiral magnet Fe1−x_{1-x}Cox_xSi

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    Small angle neutron scattering measurements on a bulk single crystal of the doped chiral magnet Fe1−x_{1-x}Cox_xSi with xx=0.3 reveal a pronounced effect of the magnetic history and cooling rates on the magnetic phase diagram. The extracted phase diagrams are qualitatively different for zero and field cooling and reveal a metastable skyrmion lattice phase outside the A-phase for the latter case. These thermodynamically metastable skyrmion lattice correlations coexist with the conical phase and can be enhanced by increasing the cooling rate. They appear in a wide region of the phase diagram at temperatures below the AA-phase but also at fields considerably smaller or higher than the fields required to stabilize the A-phase

    Editorial: Ecosystem Services and Disservices Provided by Plant-Feeding Predatory Arthropods

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    Editorial of the Research Topic issue on Ecosystem Services and Disservices Provided by Plant-Feeding Predatory Arthropod

    Universality of the helimagnetic transition in cubic chiral magnets: Small angle neutron scattering and neutron spin echo spectroscopy studies of Fe1−x_{1-x}Cox_xSi

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    We present a comprehensive Small Angle Neutron Scattering (SANS) and Neutron Spin Echo Spectroscopy (NSE) study of the structural and dynamical aspects of the helimagnetic transition in Fe1−x_{1-x}Cox_xSi with xx = 0.30. In contrast to the sharp transition observed in the archetype chiral magnet MnSi, the transition in Fe1−x_{1-x}Cox_xSi is gradual and long-range helimagnetic ordering coexists with short-range correlations over a wide temperature range. The dynamics are more complex than in MnSi and involve long relaxation times with a stretched exponential relaxation which persists even under magnetic field. These results in conjunction with an analysis of the hierarchy of the relevant length scales show that the helimagnetic transition in Fe1−x_{1-x}Cox_xSi differs substantially from the transition in MnSi and question the validity of a universal approach to the helimagnetic transition in chiral magnets

    Reversal of hepatorenal syndrome type 1 with terlipressin plus albumin vs. placebo plus albumin in a pooled analysis of the OT-0401 and REVERSE randomised clinical studies

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    Background The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available. Aim To compare the efficacy of terlipressin plus albumin vs. placebo plus albumin in patients with HRS-1. Methods Pooled patient-level data from two large phase 3, randomised, placebo-controlled studies were analysed for HRS reversal [serum creatinine (SCr) value ≤133 μmol/L], 90-day survival, need for renal replacement therapy and predictors of HRS reversal. Patients received intravenous terlipressin 1–2 mg every 6 hours plus albumin or placebo plus albumin up to 14 days. Results The pooled analysis comprised 308 patients (terlipressin: n = 153; placebo: n = 155). HRS reversal was significantly more frequent with terlipressin vs. placebo (27% vs. 14%; P = 0.004). Terlipressin was associated with a more significant improvement in renal function from baseline until end of treatment, with a mean between-group difference in SCr concentration of −53.0 μmol/L (P \u3c 0.0001). Lower SCr, lower mean arterial pressure and lower total bilirubin and absence of known precipitating factors for HRS were independent predictors of HRS reversal and longer survival in terlipressin-treated patients. Conclusions Terlipressin plus albumin resulted in a significantly higher rate of HRS reversal vs. albumin alone in patients with HRS-1. Terlipressin treatment is associated with improved renal function
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