Tribo-corrosion of steel in artificial saliva

Stainless steel is widely used as dental implant. However, there has been little work on the micro-abrasion of such materials in laboratory simulated oral environments, where abrasion, sliding wear can interact simultaneously. In this study, the effects of applied load, and exposure time were evaluated for a 316 stainless steel in a laboratory simulated artificial saliva. Polarization curves showed an enhancement of corrosion current density with increases in applied load. Wear maps were produced showing low wear safety regimes at intermediate loads and exposure times. Possible reasons for such trends are interpreted in terms of the ability of the passive film in providing resistance against third body particle impact and the concentration of particles in the contact at higher loads

Two Wrongs Don\u27t Make a Right: Federal Death Eligibility Determinations and Judicial Trifurcations

Broadly speaking, the purpose of this article is to bring attention to this radical and irreconcilable disparity between the unequivocal Sixth Amendment right of confrontation criminal defendants are afforded at trial,and the limited, qualified right of confrontation the FDPA grants federal capital defendants during death-eligibility determinations, which occur as part of the sentencing phase. It advances the argument that there is no tenable principled distinction on which this disparate procedural treatment may rest. We will attempt to demonstrate that, as written, the statutory provision that governs the admission of evidence at capital sentencings—18 U.S.C. § 3593(c)—is unconstitutional on its face as it applies to death eligibility determinations—and cannot be salvaged by judicial construction...In reaching our conclusion, this article will explore, inter alia, the extensions of our constitutionally grounded right of confrontation; that is, “[i]n all criminal prosecutions” the Confrontation Clause of the Sixth Amendment unequivocally grants the accused the right “to be confronted with the witnesses against him.”...In Part I, we will attempt to frame the problem we believe needs to be addressed: the manner in which the relaxed evidentiary standard 18 U.S.C. § 3593(c) prescribes deprives capital defendants of the full panoply of their Sixth Amendment confrontation rights during the litigation of facts that are the functional equivalent of elements of federal capital murder, inter alia, by allowing the trial judge to admit testimonial hearsay at his or her discretion. In Part II, we will explore the Supreme Court’s recent forays into what we shall call, for the purpose of this article, “functional equivalence jurisprudence,” to illustrate the constitutional significance of equating statutorily prescribed aggravating factors with elements of an offense, and its resonation with some federal district courts. In Part III, we will advance an alternative argument for applying the right of confrontation to the eligibility determination based on a careful reading of the text of the Sixth Amendment. In Part IV, we will sketch the history of the Sixth Amendment right of confrontation and explore the manner in which the Court’s holding in Crawford marked a sea change in its Sixth Amendment jurisprudence. In Part V, we will turn to Crawford’s effect on 18 U.S.C. § 3593(c).In Part VI, we will explore the recent phenomenon of judicially imposed trifurcation in an effort to address the FDPA’s constitutional shortcomings, and we will argue that that practice, whether by motion or sua sponte, is likewise unconstitutional. Finally, in Part VII, we will propose a pragmatic solution to this constitutional quandary: legislatively mandated trifurcation

Cardiovascular risk stratification in familial hypercholesterolaemia

Familial hypercholesterolaemia (FH) is a common autosomal-dominant disorder in most European countries. Patients with FH are characterised by a raised level of low-density lipoprotein cholesterol and a high risk of premature coronary heart disease (CHD). Currently there is no consensus regarding the clinical utility to predict future coronary events or testing for the presence of subclinical atherosclerotic disease in asymptomatic patients with FH. Family screening of patients with FH as recommended by the UK National Institute of Health and Care Excellence guideline would result in finding many young individuals with a diagnosis of FH who are clinically asymptomatic. The traditional CHD risk scores, that is, the Framingham score, are insufficient in risk prediction in this group of young individuals. In addition, a better understanding of the genetic aetiology of the FH phenotype and CHD risk in monogenic FH and polygenic hypercholesterolaemia is needed. Non-invasive imaging methods such as carotid intima-media thickness measurement might produce more reliable information in finding high-risk patients with FH. The potential market authorisation of novel therapeutic agents such as PCSK9 monoclonal inhibitors makes it essential to have a better screening programme to prioritise the candidates for treatment with the most severe form of FH and at higher risk of coronary events. The utility of new imaging techniques and new cardiovascular biomarkers remains to be determined in prospective trials

Elastocapillary driven assembly of particles at free-standing smectic-A films

Colloidal particles at complex fluid interfaces and within films assemble to form ordered structures with high degrees of symmetry via interactions that include capillarity, elasticity, and other fields like electrostatic charge. Here we study microparticle interactions within free-standing smectic-A films, in which the elasticity arising from the director field distortion and capillary interactions arising from interface deformation compete to direct the assembly of motile particles. New colloidal assemblies and patterns, ranging from 1D chains to 2D aggregates, sensitive to the initial wetting conditions of particles at the smectic film, are reported. This work paves the way to exploiting LC interfaces as a means to direct spontaneously formed, reconfigurable, and optically active materials.Comment: 8 pages, 6 figures. Supplementary Materials: 3 pages, 3 figure

Modeling solvent enhanced gravity drainage from a single matrix block in fractured oil reservoirs

Peer reviewedPostprin

In vitro and in vivo assessment of free radical scavenging and antioxidant activities of Veronica persica Poir

With the appearance of new disorders along with inability of some conventional therapies for the treatment of diseases without any side effects, the discovery of safe and efficient therapeutic agents is of utmost importance in the medical area. In this context, medicinal plants as promising therapeutic candidates can provide a reliable and efficient profile. Since free radicals are at the center of various disorder pathways, reducing their production or complete removal of these chemical species could be advantageous for prevention and treatment of many diseases. In this experiment, free radical scavenging and antioxidant activities of Veronica persica Poir., a known medicinal plant, were evaluated using in vitro and in vivo assays. Chemical characterization results showed a high phenolic content in the V. persica methanol extract. In addition, in vitro assays including DPPH radical-scavenging assay, nitric oxide-scavenging activity assay, hydrogen peroxide scavenging test and bleomycin-dependent DNA damage test revealed significant antioxidant power and radical scavenging capacity of this plant. In accordance, in vivo experiments showed inhibitory effects of the methanol extract on lipid peroxidation, a main cause of cell damage. Our findings revealed the promising potential of this plant in reducing free radicals through different pathways. Moreover, our data suggested a correlation between the high phenolic content of the V. persica extract and its free radical scavenging and antioxidant activities

Nitrogen bioavailability from organic amendments and cover crops in broccoli, sweet corn, and potato

Non-Peer Reviewe

Spatial Structures in a Generalized Ginzburg-Landau Free Energy

Searching for characteristic signatures of a higher order phase transition (specifically of order three or four), we have calculated the spatial profiles and the energies of a spatially varying order parameter in one dimension. In the case of a $p^{th}$ order phase transition to a superconducting ground state, the free energy density depends on temperature as $a^p$, where $a = a_o(1-T/T_c)$ is the reduced temperature. The energy of a domain wall between two degenerate ground states is $\epsilon_p \simeq a^{p-1/2}$. We have also investigated the effects of a supercurrent in a narrow wire. These effects are limited by a critical current which has a temperature dependence $J_c(T) \simeq a^{(2p-1)/2}$. The phase slip center profiles and their energies are also calculated. Given the suggestion that the superconducting transtion in \bkbox, for $x = 0.4$, may be of order four, these predictions have relevance for future experiments.Comment: 7 pages, 5 figure