Health implications of an immigration raid: findings from a Latino community in the midwestern United States.

Immigration raids exemplify the reach of immigration law enforcement into the lives of Latino community members, yet little research characterizes the health effects of these raids. We examined the health implications of an immigration raid that resulted in multiple arrests and deportations and occurred midway through a community survey of a Latino population. We used linear regression following principal axis factoring to examine the influence of raid timing on immigration enforcement stress and self-rated health. We controlled for age, sex, relationship status, years in the county in which the raid occurred, children in the home, and nativity. 325 participants completed the survey before the raid and 151 after. Completing the survey after the raid was associated with higher levels of immigration enforcement stress and lower self-rated health scores. Findings indicate the negative impact of immigration raids on Latino communities. Immigration discussions should include holistic assessments of health.UL1 TR000433 - NCATS NIH HH

Microelectronic cmos implementation of a machine learning technique for sensor calibration

An integrated machine-learning based adaptive circuit for sensor calibration implemented in standard 0.18μm CMOS technology with 1.8V power supply is presented in this paper. In addition to linearizing the device response, the proposed system is also capable to correct offset and gain errors. The building blocks conforming the adaptive system are designed and experimentally characterized to generate numerical high-level models which are used to verify the proper performance of each analog block within a defined multilayer perceptron architecture. The network weights, obtained from the learning phase, are stored in a microcontroller EEPROM memory, and then loaded into each of the registers of the proposed integrated prototype. In order to verify the proposed system performance, the non-linear characteristic of a thermistor is compensated as an application example, achieving a relative error er below 3% within an input span of 130°C, which is almost 6 times less than the uncorrected response. The power consumption of the whole system is 1.4mW and it has an active area of 0.86mm 2 . The digital programmability of the network weights provides flexibility when a sensor change is required

On the Effect of Correlation on the Capacity of Backscatter Communication Systems

We analyse the effect of correlation between the forward and backward links on the capacity of backscatter communication systems. To that aim, we obtain an analytical expression for the average capacity under a correlated Rayleigh product fading channel, as well as closed-form asymptotic expressions for the high and low signal-to-noise ratio (SNR) regimes. Our results show that correlation is indeed detrimental for a fixed target SNR; contrarily to the common belief, we also see that correlation can be actually beneficial in some instances when a fixed power budget is considered.Comment: This work has been submitted for publication. Copyright may be transferred without notice, after which this version may no longer be accessibl

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2

The Fanconi Anemia (FA) pathway is important for the repair of DNA interstrand crosslinks (ICL). The FANCD2-FANCI complex is central to the pathway, and localizes to ICLs dependent on its monoubiquitination. It has remained elusive whether the complex is recruited before or after the critical monoubiquitination. Here we report the first structural insight into the human FANCD2-FANCI complex by obtaining the cryo- EM structure. The complex contains an inner cavity, large enough to accommodate a double stranded DNA helix, as well as a protruding Tower domain. Disease-causing mutations in the Tower domain is observed in several FA patients. Our work reveals that recruitment of the complex to a stalled replication fork serves as the trigger for the activating monoubiquitination event. Taken together, our results uncover the mechanism of how the FANCD2-FANCI complex activates the FA pathway, and explains the underlying molecular defect in FA patients with mutations in the Tower domain

Incorporating Biotic Information in Species Distribution Models: A Coregionalized Approach

In this work, we discuss the use of a methodological approach for modelling spatial relationships among species by means of a Bayesian spatial coregionalized model. Inference and prediction is performed using the integrated nested Laplace approximation methodology to reduce the computational burden. We illustrate the performance of the coregionalized model in species interaction scenarios using both simulated and real data. The simulation demonstrates the better predictive performance of the coregionalized model with respect to the univariate models. The case study focus on the spatial distribution of a prey species, the European anchovy (Engraulis encrasicolus), and one of its predator species, the European hake (Merluccius merluccius), in the Mediterranean sea. The results indicate that European hake and anchovy are positively associated, resulting in improved model predictions using the coregionalized model.Postprin