Consistent two--dimensional chiral gravity

We study chiral induced gravity in the light-cone gauge and show that the theory is consistent for a particular choice of chiralities. The corresponding Kac--Moody central charge has no forbidden region of complex values. Generalized analysis of the critical exponents is given and their relation to the $SL(2,R)$ vacuum states is elucidated. All the parameters containing information about the theory can be traced back to the characteristics of the group of residual symmetry in the light--cone gauge.Comment: 38 pages, LateX, to appear in Int.J.Mod.Phys.

A Submillimeter HCN Laser in IRC+10216

We report the detection of a strong submillimeter wavelength HCN laser line at a frequency near 805 GHz toward the carbon star IRC+10216. This line, the J=9-8 rotational transition within the (04(0)0) vibrationally excited state, is one of a series of HCN laser lines that were first detected in the laboratory in the early days of laser spectroscopy. Since its lower energy level is 4200 K above the ground state, the laser emission must arise from the inner part of IRC+10216's circumstellar envelope. To better characterize this environment, we observed other, thermally emitting, vibrationally excited HCN lines and find that they, like the laser line, arise in a region of temperature approximately 1000 K that is located within the dust formation radius; this conclusion is supported by the linewidth of the laser. The (04(0)0), J=9-8 laser might be chemically pumped and may be the only known laser (or maser) that is excited both in the laboratory and in space by a similar mechanism.Comment: 11 pages, 3 figure

Complex flavour couplings in supersymmetry and unexpected CP-violation in the decay B -> phi K

Complex flavour couplings (off-diagonal mass terms) in the squark sector of supersymmetric theories may drastically alter both the rate and the CP-violating asymmetry of certain B-meson decays. We consider the effects of couplings that induce b -> s transitions and lead to final state with strangeness one. We investigate the bounds that must be satisfied by the new terms and explore the possible implications on direct and mixing induced asymmetries in the charged and neutral B -> J/Psi K and B -> phi K decays.Comment: 14 pages, 3 figure

A novel integral representation for the Adler function

New integral representations for the Adler D-function and the R-ratio of the electron-positron annihilation into hadrons are derived in the general framework of the analytic approach to QCD. These representations capture the nonperturbative information encoded in the dispersion relation for the D-function, the effects due to the interrelation between spacelike and timelike domains, and the effects due to the nonvanishing pion mass. The latter plays a crucial role in this analysis, forcing the Adler function to vanish in the infrared limit. Within the developed approach the D-function is calculated by employing its perturbative approximation as the only additional input. The obtained result is found to be in reasonable agreement with the experimental prediction for the Adler function in the entire range of momenta $0 \le Q^2 < \infty$.Comment: 11 pages, 3 figure

MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells

We have previously reported a strong correlation between poor prognosis in childhood neuroblastoma (NB) patients and high-level expression of the transmembrane efflux pump, Multidrug Resistance-associated Protein (MRP1), in NB tumour tissue. In this study, we inhibited the endogenous expression of MRP1 in 2 different NB tumour cell lines by stably transfecting an MRP1 antisense expression vector (MRP-AS). Compared with control cells, MRP-AS transfectant cells demonstrated a higher proportion of dead and morphologically apoptotic cells, spontaneous neuritogenesis, and, increased synaptophysin and neurofilament expression. Bcl-2 protein expression was markedly reduced in MRP-AS cells compared to controls. Conversely, we found that the same NB tumour cell line overexpressing the full-length MRP1 cDNA in sense orientation (MRP-S) demonstrated resistance to the neuritogenic effect of the differentiating agent, all-trans-retinoic acid. Taken together, the results suggest that the level of MRP1 expression in NB tumour cells may influence the capacity of NB cells for spontaneous regression in vivo through cell differentiation and death. © 2001 Cancer Research Campaign  http://www.bjcancer.co

Ubiquitous CP violation in a top-inspired left-right model

We explore CP violation in a Left-Right Model that reproduces the quark mass and CKM rotation angle hierarchies in a relatively natural way by fixing the bidoublet Higgs VEVs to be in the ratio m_b:m_t. Our model is quite general and allows for CP to be broken by both the Higgs VEVs and the Yukawa couplings. Despite this generality, CP violation may be parameterized in terms of two basic phases. A very interesting feature of the model is that the mixing angles in the right-handed sector are found to be equal to their left-handed counterparts to a very good approximation. Furthermore, the right-handed analogue of the usual CKM phase delta_L is found to satisfy the relation delta_R \approx delta_L. The parameter space of the model is explored by using an adaptive Monte Carlo algorithm and the allowed regions in parameter space are determined by enforcing experimental constraints from the K and B systems. This method of solution allows us to evaluate the left- and right-handed CKM matrices numerically for various combinations of the two fundamental CP-odd phases in the model. We find that all experimental constraints may be satisfied with right-handed W and Flavour Changing Neutral Higgs masses as low as about 2 TeV and 7 TeV, respectively.Comment: 37 pages, 13 figure

Mixed Bino-Wino-Higgsino Dark Matter in Gauge Messenger Models

Almost degenerate bino and wino masses at the weak scale is one of unique features of gauge messenger models. The lightest neutralino is a mixture of bino, wino and higgsino and can produce the correct amount of the dark matter density if it is the lightest supersymmetric particle. Furthermore, as a result of squeezed spectrum of superpartners which is typical for gauge messenger models, various co-annihilation and resonance regions overlap and very often the correct amount of the neutralino relic density is generated as an interplay of several processes. This feature makes the explanation of the observed amount of the dark matter density much less sensitive to fundamental parameters. We calculate the neutralino relic density assuming thermal history and present both spin independent and spin dependent cross sections for the direct detection. We also discuss phenomenological constraints from b to s gamma and muon g-2 and compare results of gauge messenger models to well known results of the mSUGRA scenario.Comment: 27 pages, 9 figures, references added, version to appear at JCA