577 research outputs found
Antecedents and consequences of parental psychological control and autonomy support: the role of psychological basic needs
Research suggest that psychologically controlling and autonomy supportive parenting can be described within the SDT's framework. Two studies were conducted to examine: (a) the role of parental need frustration as a predictor of parental psychological control, (b) the role of parental need satisfaction as a predictor of parental autonomy support and (c) the role of parents' psychological control and autonomy support in the intergenerational transmission of satisfaction and frustration of the psychological basic needs. Study-1 provided evidence, in a sample of 203 Italian coupled parents, that needs frustration and needs satisfaction represent distinct antecedents of psychological control and autonomy support. Study-2, showed that in 135 families, the intergenerational association between parents' and adolescents' need frustration was partial mediated by psychological control and autonomy support. Results clearly showed that parents who experienced high level of psychological needs frustration are more likely to use psychological control and in turn to promote a feeling of need frustration in their adolescents; differently, parents who experienced high levels of psychological needs satisfaction tend to exert more autonomy support in their relationship with their children and in turn adolescents tend to perceive higher level of needs satisfaction. These findings are discussed in light of SDT and underline the importance of needs in the parenting context and have implications for interventions
The Role of parental control and Coping Strategies on adolescents\u2019 problem behaviors
The current study was aimed at contributing to the understanding of the role of perceived parental monitoring, psychological
control, and coping strategies on adolescents\u2019 problem behaviors, in terms of anxiety and drinking behavior. Participants were
541 high school students, 17 to 19-year old (M = 17.09, SD = 0.80) high school students in Sicily and Calabria (Italy).
Participants completed self-report measures assessing parental monitoring, psychological control, coping strategies (i.e., TaskOriented, Emotion-Oriented, and Avoidance-Oriented). Results of the path analysis showed that coping strategies play a mediating role in the association between parental psychological control and both adolescents\u2019 anxiety and drinking behavior.
Furthermore, a direct positive association was reported from parental psychological control and anxiety, while a negative direct
association was reported from parental monitoring to drinking behavior. Results of this study provide a comprehensive model that
showed that the different coping strategies could explain the psychological mechanisms that underline the associations between
two different kinds of parental control (psychological control and monitoring) and both internalizing and externalizing adolescents\u2019 form of maladjustment (e.g. anxiety and drinking behaviors). Overall, coping strategies seem to be a fruitful target for the
prevention programs for adolescents\u2019 anxiety and drinking behaviors
RESCUE MANAGEMENT AND ASSESSMENT OF STRUCTURAL DAMAGE BY UAV IN POST-SEISMIC EMERGENCY
Abstract. The increasing frequency of emergencies urges the need for a detailed and thorough knowledge of the landscape. The first hours after a disaster are not only chaotic and problematic, but also decisive to successfully save lives and reduce damage to the building stock. One of the most important factors in any emergency response is to get an adequate awareness of the real situation, what is only possible after a thorough analysis of all the available information obtained through the Italian protocol Topography Applied to Rescue. To this purpose geomatic tools are perfectly suited to create, manage and dynamically enrich an organized archive of data to have a quick and functional access to information useful for several types of analysis, helping to develop solutions to manage the emergency and improving the success of rescue operations. Moreover, during an emergency like an earthquake, the conventional inspection to assess the damage status of buildings requires special tools and a lot of time. Therefore, given the large number of buildings requiring safety measures and rehabilitation, efficient use of limited resources such as time and equipment, as well as the safety of the involved personnel are important aspects. The applications shown in the paper are intended to underline how the above-mentioned objective, in particular the rehabilitation interventions of the built heritage, can be achieved through the use of data acquired from UAV platform integrated with geographic data stored in GIS platforms
PEEK versus metal cages in posterior lumbar interbody fusion: a clinical and radiological comparative study
Background: Low back pain and sciatica represent a common disabling condition with a significant impact on the social, working and economic lives of patients. Transforaminal lumbar interbody fusion (TLIF) is a surgical procedure used in degenerative spine conditions. Several types of cages were used in the TLIF procedure. Purpose: To determine whether there is a difference in terms of symptomatology improvement, return to daily activities and fusion rate between metal cages and polyetheretherketone (PEEK) cages. Methods: We have retrospectively reviewed 40 patients who have undergone TLIF from October 2015 to May 2016. All patients were clinically evaluated with questionnaires and were assessed with CT scan and standing X-ray films of the full-length spine. Results: We found no significant functional differences in the two groups. At 1-year follow-up, osteolysis was present in 50% of cases of the PEEK cages and in 10% cases of the metal cages. The degree of fusion at 1 year was evaluated as complete in 40% cases of the metal cages and 15% cases of the PEEK cages. Conclusions: We have found a better fusion rate and prevalence of fusion in the group treated with metal cages, reflecting the well-known osteoinductive properties of titanium and tantalum
Arthroscopic-guided balloon tibioplasty in schatzker iii tibial plateau fracture
Purpose The study aims to present the results at a mean 28-months follow-up of arthroscopic-guided balloon tibioplasty and to spot some technical tricks and some practice using tools and materials. Methods The study relates to six patients with tibial plateau fractures type Schatzker III with tibial plateau depression more than 4 mm at preoperative computed tomography scan (CT-scan). The follow-up period ranged from 22 to 33 months, with a mean of 28 months. No patients were lost to follow-up. The patients were evaluated clinically using the Rasmussen score system and Lysholm score systems at 6 to 12 and 24 months, postoperatively. Radiographic evaluations (standard X-rays) were done preoperatively at 1, 3, and 12 months postoperatively while a CT-scan with 3D reconstruction was performed preoperatively, at the first day and 6 months, postoperatively. Results The mean Rasmussen clinical score at 6 months postoperatively was 26.3 while at 1-year postoperatively the mean Rasmussen clinical score was 28.33. At 2-year postoperatively the mean Rasmussen clinical score was 28.83. Statistically significant difference was found in 6-months and 2-years results (p < 0.05). CT-scan achieved the first postoperative day showed the recovery of approximately 70% of the area of the interested tibial plateau, restoring of the joint surface without articular bone free fragments. Conclusion The described surgical procedure, if correctly performed with proper indications (Schatzker III), respect the principles mentioned above and the clinical and radiological results confirm our purpose. Level of Evidence This is a therapeutic case series, level IV study
Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-gamma
Leukotrienes (LT) and prostaglandins (PG) are proinflammatory mediators generated by the conversion of arachidonic acid via 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It has long been proposed that the inhibition of the 5-LO could enhance the COX pathway leading to an increased PG generation. We have found that in in vitro models of inflammation, such as mice-elicited peritoneal macrophages activated with lipopolysaccharide (LPS)/interferon- γ (IFN-γ), the deletion of the gene encoding for 5-LO or the enzyme activity inhibition corresponded to a negative modulation of the COX pathway. Moreover, exogenously added LTC4, but not LTD4, LTE 4, and LTB4, was able to increase PG production in stimulated cells from 5-LO wild-type and knockout mice. LTC4 was not able to induce COX-2 expression by itself but rather potentiated the action of LPS/IFN-γ through the extracellular signal-regulated kinase-1/2 activation, as demonstrated by the use of a specific mitogen-activated protein kinase (MAPK) kinase inhibitor. The LT-induced increase in PG generation, as well as MAPK activation, was dependent by a specific ligand-receptor interaction, as demonstrated by the use of a cys-LT1 receptor antagonist, although also a direct action of the antagonist used, on PG generation, cannot be excluded. Thus, the balance between COX and 5-LO metabolites could be of great importance in controlling macrophage functions and consequently, inflammation and tumor promotion
Technological addiction in adolescents: the interplay between parenting and psychological basic needs
lthough technological addictions, similar to other behavioural addictions, share psychosocial risk factors with substance-related addictions, the studies on the interplay between contextual and personal variables in the prediction of technological addictions are still limited. For this reason, in accordance with Self-Determination Theory (SDT), the aim of this study was to examine the integrated role of parental psychological control and parental autonomy with need satisfaction and need frustration in the understanding of technological addictions (internet addiction, gaming addiction, smartphone addiction, and social network addiction) in adolescents. Using a sample of 482 adolescents (200 males) with an age range between 14 and 17, path analyses showed that both parental psychological control and need frustration predicted all the technological addictions examined. Furthermore, indirect effects from psychological control to all technological addictions through need frustration were also found. The findings are discussed in line with the SDT
Evaluation of a Gel Containing a Propionibacterium Extract in an In Vivo Model of Wound Healing
Inappropriate wound healing (WH) management can cause significant comorbidities, especially in patients affected by chronic and metabolic diseases, such as diabetes. WH involves several different, partially overlapping processes, including hemostasis, inflammation, cell proliferation, and remodeling. Oxidative stress in WH contributes to WH impairment because of the overexpression of radical oxygen species (ROS) and nitrogen species (RNS). This study aimed to evaluate the in vitro antioxidative action of a gel containing a Propionibacterium extract (Emorsan (R) Gel) and assess its skin re-epithelialization properties in a mouse model of WH. The scavenging effects of the bacterial extract were assessed in vitro through the ABTS and DPPH assays and in L-929 murine fibroblasts. The effects of the Emorsan (R) Gel were studied in vivo in a murine model of WH. After WH induction, mice were treated daily with vehicle or Emorsan (R) Gel for 6 or 12 days. According to the in vitro tests, the Propionibacterium extract exerted an inhibitory effect on ROS and RNS, consequently leading to the reduction in malondialdehyde (MDA) and nitrite levels. Before proceeding with the in vivo study, the Emorsan (R) Gel was verified to be unabsorbed. Therefore, the observed effects could be ascribed to a local action. The results obtained in vivo showed that through local reduction of oxidative stress and inflammation (IL-1 beta, TNF-alpha), the Emorsan (R) Gel significantly reduced the infiltration of mast cells into the injured wound, leading to the amelioration of symptoms such as itch and skin irritation. Therefore, the Emorsan (R) Gel improved the speed and percentage of wound area closure by improving the tissue remodeling process, prompting vascular-endothelial growth factor (VEGF) and transforming growth factor (TGF)-beta production and reducing the expression of adhesion molecules. Emorsan (R) Gel, by its ability to inhibit free radicals, could reduce local inflammation and oxidative stress, thus enhancing the speed of wound healing
Trauma coagulopathy and its outcomes
Background and Objectives: Trauma coagulopathy begins at the moment of trauma. This study investigated whether coagulopathy upon arrival in the emergency room (ER) is correlated with increased hemotransfusion requirement, more hemodynamic instability, more severe anatomical damage, a greater need for hospitalization, and hospitalization in the intensive care unit (ICU). We also analyzed whether trauma coagulopathy is correlated with unfavorable indices, such as acidemia, lactate increase, and base excess (BE) increase. Material and Methods: We conducted a prospective, monocentric, observational study of all patients (n = 503) referred to the Department of Emergency and Acceptance, IRCCS Fondazione Policlinico San Matteo, Pavia, for major trauma from 1 January 2018 to 30 January 2019. Results: Of the 503 patients, 204 had trauma coagulopathy (group 1), whereas 299 patients (group 2) did not. Group 1 had a higher hemotransfusion rate than group 2. In group 1, 15% of patients showed hemodynamic instability compared with only 8% of group 2. The shock index (SI) distribution was worse in group 1 than in group 2. Group 1 was more often hypotensive, tachycardic, and with low oxygen saturation, and had a more severe injury severity score than group 2. In addition, 47% of group 1 had three or more body districts involved compared with 23% of group 2. The hospitalization rate was higher in group 1 than in group 2 (76% vs. 58%). The length of hospitalization was >10 days for 45% of group 1 compared with 28% of group 2. The hospitalization rate in the ICU was higher in group 1 than in group 2 (22% vs. 14.8%). The average duration of ICU hospitalization was longer in group 1 than in group 2 (12.5 vs. 9.78 days). Mortality was higher in group 1 than in group 2 (3.92% vs. 0.98%). Group 1 more often had acidemia and high lactates than group 2. Group 1 also more often had BE <−6. Conclusions: Trauma coagulopathy patients, upon arrival in the ER, have greater hemotransfusion (p = 0.016) requirements and need hospitalization (p = 0.032) more frequently than patients without trauma coagulopathy. Trauma coagulopathy seems to be more present in patients with a higher injury severity score (ISS) (p = 0.000) and a greater number of anatomical districts involved (p = 0.000). Head trauma (p = 0.000) and abdominal trauma (p = 0.057) seem related to the development of trauma coagulopathy. Males seem more exposed than females in developing trauma coagulopathy (p = 0.018). Upon arrival in the ER, the presence of tachycardia or alteration of SI and its derivatives can allow early detection of patients with trauma coagulopathy
Effects of Liver × receptor agonist treatment on signal transduction pathways in acute lung inflammation
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