1,970 research outputs found

    Fortuna e abilità in 65 anni di serie A

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    Introduzione – 1. Come posizionare i Campionati di Serie A lungo il continuum fortuna/abilità – 2. L’andamento della fortuna nel tempo – 3. Quali fattori dietro la fortuna: ipotesi di ricerca – 4. I fattori che spiegano il peso della fortuna in Serie A – 5. Fortuna e media spettatori – 6. Il Campionato di Serie A 2010/11 in chiave diacronica e in ottica europea – 7. I campionati e le squadre più (e meno) fortunati – Conclusioni – Bibliografiafortuna, abilità, campionato di calcio di serie A

    The cohesion of committees is key in determining their legislative effectiveness

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    The role played by legislative committees in parliamentary democracies is a rather underestimated topic. After all, legislative standing committees exist in almost all parliamentary democracies. Still, they can have an impact on our understanding of how a democracy works. Luigi Curini explains what exactly it encompasses, and argues that the similarity of committee members’ preferences represents the most important factor in deciding the effectiveness of committee work

    I FONDI SPECULATIVI: PROFILI EVOLUTIVI E STRATEGIE DI INVESTIMENTO.

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    Il presente studio si concentra sull’analisi dei Fondi Speculativi, versione italiana dei più noti Hedge Funds. L’introduzione nel nostro ordinamento dei Fondi Speculativi rappresenta una forte novità per l’arricchimento delle opportunità di investimento disponibili per gli investitori e per le diverse logiche di gestione cui gli intermediari sono obbligati nel provvedere alla loro offerta. Dopo aver delineato in termini evolutivi il quadro normativo in materia di fondi comuni di investimento, si propone una disamina sia degli aspetti strutturali, sia delle peculiari strategie di investimento adottate dagli Hedge Funds; tali fondi si caratterizzano infatti per l’adozione di una varietà enorme di strategie di investimento, con caratteristiche di rischio/rendimento molto differenziate tra di loro. Il lavoro si completa poi con un’analisi quali-quantitativa dell’asset management industry in Italia, con particolare attenzione ai profili evolutivi del patrimonio gestito dai Fondi Speculativi di diritto italiano e, soprattutto, alle performance da questi realizzate nel corso del 2007, distinguendo in relazione alle singole strategie di investimento adottate

    Risk assessment, and carcinogen mutagen for workers potentially exposed in the research laboratories of “Sapienza” University of Rome for Health Surveillance

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    The following work is meant to represent the evaluation of risk factors for the health of exposed workers, arising from the management of carcinogenic and mutagenic substances, through the use of algorithms. In some places of work as a research laboratory, it is more suitable a theoretical and practical methodology (algorithm) which allows a "timely" exposure assessment. The methodology developed and used is able to determine the level of risk of exposure due to a single agent and / or to more agents. Results obtained by the algorithm, have shown an higher exposure to 1 for formaldehyde (Lcanc = 1.32), while for acrylamide results obtained shows a lower exposure to 1 (Lcanc = 0.528). Although the overall exposure level of studied workers higher value to 1 (Lcanc= 1.848), the Occupational Medicine Centre of "Sapienza" - University of Rome, in agreement with the position taken by the Italian Society of Occupational Medicine and Industrial Hygiene applies health surveillance even in the presence of potential health risk reducing it among the general protection measures the health and safety of workers

    Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy

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    A case of pleuropneumonia is reported in an adult male bottlenose dolphin (Tursiops truncatus) found stranded in 2014 along the Central Adriatic coast of Italy. A severe pyogranulomatous pneumonia and thoracic lymphadenopathy were present at necropsy. Numerous Splendore-Hoeppli bodies were found microscopically scattered throughout the lung. Histochemical evidence of Actinomyces-like organisms was obtained from the pulmonary parenchyma, with a strain of Photobacterium damselae subsp. piscicida and Ureaplasma spp. being also isolated from the same tissue. For the latter, a genome fragment of approximately 1400 bp from the 16s rDNA was amplified and sequenced. BLAST analysis revealed 100% identity with an uncultured Ureaplasma spp. (JQ193826.1)

    Meccanismi di Evoluzione del Cariotipo nei Monocelididi (Turbellaria Proseriata)

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    Mechanisms of karyotype evolution in the Monocelididae (Turbellaria Proseriata). Within the Proseriata (Turbellaria: Seriata), the family Monocelididae displays several interesting patterns of chromosomal evolution. A basic set of n = 3 -made up or one large metacentric, one medium-sized metacentric and one small clearly heterobrachial chromosome -has been detected. It is widely distributed in species pertaining to both the subfamilies in which the Monocelididae are subdivided. From this basic set, other complements -either with n = 3 or n > 3 -would be originated.Several karyological mechanisms or common occurrence within the family (translocations, small chromosome rearrangements involving the centromere, genome growth) have been detected. As to the chromosome complements with n > 3 -occurring within the subfamily Monocelidinae -they can be interpreted as the result of a fission of one or both the metacentric chromosomes of the basic set. Karyometrical data are in good agreement with this suggestion. Centric fusion or polyploidy, well known for fresh- water Triclads, have been never found in the family

    Mitochondrial DNA reveals genetic structuring of <i>Pinna nobilis</i> across the Mediterranean Sea

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    Pinna nobilis is the largest endemic Mediterranean marine bivalve. During past centuries, various human activities have promoted the regression of its populations. As a consequence of stringent standards of protection, demographic expansions are currently reported in many sites. The aim of this study was to provide the first large broad-scale insight into the genetic variability of P. nobilis in the area that encompasses the western Mediterranean, Ionian Sea, and Adriatic Sea marine ecoregions. To accomplish this objective twenty-five populations from this area were surveyed using two mitochondrial DNA markers (COI and 16S). Our dataset was then merged with those obtained in other studies for the Aegean and Tunisian populations (eastern Mediterranean), and statistical analyses (Bayesian model-based clustering, median-joining network, AMOVA, mismatch distribution, Tajima’s and Fu’s neutrality tests and Bayesian skyline plots) were performed. The results revealed genetic divergence among three distinguishable areas: (1) western Mediterranean and Ionian Sea; (2) Adriatic Sea; and (3) Aegean Sea and Tunisian coastal areas. From a conservational point of view, populations from the three genetically divergent groups found may be considered as different management units

    Peptides binding cocaine: A strategy to design biomimetic receptors

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    A computational methodology for designing and rationalizing the selection of small peptides as biomimetic receptors for cocaine is proposed. The method started by searching and filtering proteins X-ray and NMR data of biological receptor-cocaine complexes. On the basis of different cocaine zones, the amino acids involved in biological binding sites were selected as pivots to design an initial library of 768 penta-peptides. The peptides flexibility was studied determining the minimum number of conformers required to make a reliable computed binding score. The 25 highest ranked penta-peptides were selected and used as starting point to generate a 3000 hexapeptides library by inserting each of the 20 natural amino acids in all sequence positions. All structures were energy minimized and docking runs were carried out using FRED tool from OpenEye scientific. The binding scores calculated by FRED were compared with a preliminary in vivo experimental test, using two different peptides as selective sorbent material used for cocaine in Solid Phase Extraction (SPE) technique coupled with Mass Spectrometry (MS). The simulation data were found to be in agreement with experimental laboratory results, supporting the methodology proposed in this work. © 2013 Perez G, et al

    Analisi della struttura genetica di <i>Hediste diversicolor</i> (Polychaeta, Nereididae) nel Mediterraneo occidentale mediante marcatori ISSR

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    La struttura genetica del polichete Hediste diversicolor del Mediterraneo occidentale è stata studiata utilizzando gli ISSR (Inter Simple Sequence Repeats) come marcatori genetici. Sono stati raccolti 30 individui in ciascuna delle seguenti località: Stagno di Calich (Sardegna N-O), Baia di Figari (Corsica S-O), Migliacciaru (Corsica E), Fiume Morto (Toscana N-O) e Coltano (Toscana N-O). L'MDS applicato alle distanze genetiche individuali ha mostrato elevata diversità tra gli individui, ma non ha messo in evidenza alcuna sottostrutturazione genetica nelle popolazioni. Un forte segnale della divergenza genetica tra le popolazioni è dato dal fatto che il 37% del numero totale di bande rilevato è costituito da bande private, cioè esclusive di una popolazione. La varianza genetica, analizzata mediante AMOVA, è risultata equamente ripartita nelle componenti intra- e inter-popolazione (rispettivamente 46.9% e 53.1%). La Φ-statistica ha evidenziato la divergenza genetica tra le popolazioni (Φst = 0.469, P&lt;0.001). La notevole divergenza genetica tra le popolazioni di H. diversicolor è determinata in primo luogo dalla frammentazione naturale dell'habitat che produce isolamento con virtuale assenza di flusso genico tra le popolazioni. L'assenza di sottostrutturazione delle popolazioni, invece, conferma le osservazioni fatte in passato sulla dispersione degli adulti e delle postlarve all'interno dei singoli biotopi
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