When Should Screening Mammograms Begin?

When Should Screening Mammograms Begin? Michaela Cragle Lynn Blazaskie M.S., R.T. (R) (ARRT) Abstract Screening mammograms are imaging exams performed yearly to evaluate breast tissue. As women age, changes in breast tissue can be normal or can be an early sign of cancer. The age women should begin screening mammograms is not clear. According to literature it has created much controversy over the years. Most women begin the screening process at the age of 40, and even earlier depending on family history. Research groups from multiple institutions followed and evaluated women who received yearly mammograms. Most women were divided into groups based on age to see if recalls, breast cancer, or biopsies were more common in specific age groups. Some would say that the amount of recalls and biopsies that happen are excessive, and are being too cautious. Results showed that women of younger ages tend to get called back more for benign findings rather than women who are older. This research demonstrates that if cancer can be detected at an earlier age, the outcome for the patient is better. Being a little more cautious is better than overlooking something that could potentially become worse. The age at which screening mammograms should begin may change in the future as technology advances and research is ongoing. Keywords: screening mammogram, recall, benign, cancer, biopsy, age, controversy, family history, earlyhttps://digitalcommons.misericordia.edu/medimg_seniorposters/1040/thumbnail.jp

Age-Based Methods to Explore Time-Related Variables in Occupational Epidemiology Studies

Although age is recognized as the strongest predictor of mortality in chronic disease epidemiology, a calendar-based approach is often employed when evaluating time-related variables. An age-based analysis file, created by determining the value of each time-dependent variable for each age that a cohort member is followed, provides a clear definition of age at exposure and allows development of diverse analytic models. To demonstrate methods, the relationship between cancer mortality and external radiation was analyzed with Poisson regression for 14,095 Oak Ridge National Laboratory workers. Based on previous analysis of this cohort, a model with ten-year lagged cumulative radiation doses partitioned by receipt before (dose-young) or after (dose-old) age 45 was examined. Dose-response estimates were similar to calendar-year-based results with elevated risk for dose-old, but not when film badge readings were weekly before 1957. Complementary results showed increasing risk with older hire ages and earlier birth cohorts, since workers hired after age 45 were born before 1915, and dose-young and dose-old were distributed differently by birth cohorts. Risks were generally higher for smokingrelated than non-smoking-related cancers. It was difficult to single out specific variables associated with elevated cancer mortality because of: (1) birth cohort differences in hire age and mortality experience completeness, and (2) time-period differences in working conditions, dose potential, and exposure assessment. This research demonstrated the utility and versatility of the age-based approach

Prospective evaluation of voice outcome during the first two years in male patients treated by radiotherapy or laser surgery for T1a glottic carcinoma

In this prospective cohort study, we assessed voice outcome in patients before and up to 2 years after treatment for early glottic cancer either by radiotherapy or by laser surgery; 106 male patients, treated for T1aN0M0 glottic cancer either by endoscopic laser surgery (n = 67) or by radiotherapy (n = 39), participated in the study. Patients’ voices were recorded and analysed pre-treatment and 3, 6, 12 and 24 months post-treatment at their routine visit at the outpatient clinic. Average fundamental frequency (F0), percent jitter, percent shimmer and normalized noise energy (NNE) were determined. After 2 years, local control rate was 95% in the radiotherapy group and 97% in the laser surgery group. Larynx preservation rate was 95% after radiotherapy and 100% after laser surgery. Voice outcome recovers more quickly in patients treated with laser surgery in comparison to radiotherapy: 3 months after laser surgery there is no longer a difference with regard to normal voices except for the fundamental frequency, which remains higher pitched, even in the longer term. For patients treated with radiotherapy it takes longer for jitter, shimmer and NNE to become normal, where jitter remains significantly different from normal voices even after 2 years. According to these results, we believe that laser surgery is the first treatment of choice in the treatment of selected cases of T1a glottic carcinomas with good functional and oncological results

Evidence‐based review of treatment options for patients with glottic cancer

Evidence‐based medicine integrates the best available data in decision making, with the goal of minimizing physicians' and patients' subjectivity. In 2006, the American Society of Clinical Oncology edited clinical practice guidelines for the use of larynx preservation strategies. The objective of this review was to evaluate the current levels of evidence for glottic squamous cell carcinoma. Current guidelines for early stage glottic cancer are based on low‐level evidence. Conservation surgery (open or transoral) and radiation therapy are all valid options for T1 and selected T2 lesions. For advanced lesions, surgery and combined chemotherapy and radiation are options. High‐level evidence favors combined chemotherapy and radiation therapy or altered fractionation radiation therapy as nonsurgical strategies for organ preservation, compared with radiation therapy alone. The optimal combination of chemotherapy, targeted therapy, and radiation therapy remains to be demonstrated, however, and for high‐volume tumors, total laryngectomy may still be warranted. © 2011 Wiley Periodicals, Inc. Head Neck, 2011Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87151/1/21528_ftp.pd

The Mineral Balance in Semen and Some of Its Effects on The Metabolic Activity of Bull Spermatozoa

113 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1957.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD