Introducing the Dark Energy Universe Simulation Series (DEUSS)

In this "Invisible Universe" proceedings, we introduce the Dark Energy Universe Simulation Series (DEUSS) which aim at investigating the imprints of realistic dark energy models on cosmic structure formation. It represents the largest dynamical dark energy simulation suite to date in term of spatial dynamics. We first present the 3 realistic dark energy models (calibrated on latest SNIa and CMB data): LambdaCDM, quintessence with Ratra-Peebles potential, and quintessence with Sugra potential. We then isolate various contributions for non-linear matter power spectra from a series of pre-DEUSS high-resolution simulations (130 million particles). Finally, we introduce DEUSS which consist in 9 Grand Challenge runs with 1 billion particles each thus probing scales from 4 Gpc down to 3 kpc at z=0. Our goal is to make these simulations available to the community through the "Dark Energy Universe Virtual Observatory" (DEUVO), and the "Dark Energy Universe Simulations" (DEUS) consortium.Comment: 6 pages, 3 figures, to appear in the AIP proceedings of the 'Invisible Universe International Conference', UNESCO-Paris, June 29-July 3, 200

Міхал Бобжинський: суспільно-політична діяльність

Розглянута суспільно-політична діяльність визначного представника краківської історичної школи М. Бобжинського. Акцентовано увагу на зв’язку наукових поглядів історика з його політичною практикою. Охарактеризовано дискусії, які досьогодні точаться серед науковців щодо оцінки результатів його діяльності.Рассмотрена общественно-политическая деятельность выдающегося представителя краковской исторической школы М. Бобжинского. Акцентировано внимание на связи научных взглядов историка с его политической практикой. Охарактеризованы дискуссии, которые досегодня ведутся среди ученых относительно оценки результатов его деятельности.The socio-political activities of M. Bobzhynski – a prominent representative of the Krakow historical school – are reviewed. Attention is given to the connection of the historian scholarly views with his political practice. The discussions that until now are going on among scholars in evaluating the results of his work are characterised

From "retailers" to health care providers: Transforming the role of community pharmacists in chronic disease management

© 2015. Community pharmacists are the third largest healthcare professional group in the world after physicians and nurses. Despite their considerable training, community pharmacists are the only health professionals who are not primarily rewarded for delivering health care and hence are under-utilized as public health professionals. An emerging consensus among academics, professional organizations, and policymakers is that community pharmacists, who work outside of hospital settings, should adopt an expanded role in order to contribute to the safe, effective, and efficient use of drugs-particularly when caring for people with multiple chronic conditions. Community pharmacists could help to improve health by reducing drug-related adverse events and promoting better medication adherence, which in turn may help in reducing unnecessary provider visits, hospitalizations, and readmissions while strengthening integrated primary care delivery across the health system. This paper reviews recent strategies to expand the role of community pharmacists in Australia, Canada, England, the Netherlands, Scotland, and the United States. The developments achieved or under way in these countries carry lessons for policymakers world-wide, where progress thus far in expanding the role of community pharmacists has been more limited. Future policies should focus on effectively integrating community pharmacists into primary care; developing a shared vision for different levels of pharmacist services; and devising new incentive mechanisms for improving quality and outcomes

Large Deformation Effects in the N = Z 44Ti Compound Nucleus

The N = Z 44Ti* nucleus has been populated in Fusion Evaporation process at very high excitation energies and angular momenta using two entrance channels with different mass-asymmetry. The deformation effects in the rapidly rotating nuclei have been investigated through the energy distribution of the alpha-particle combined to statistical-model calculations. In the case of low-multiplicity events, the ratio between first particle emitted has been measured and shows significant disagreement with the predictions of the statistical-model. This may explain The large discrepancies observed in proton energy spectra measured in previous experiments performed in the same mass region.Comment: Proceeding of the 10th International Conference on Nuclear Reaction Mechanisms, Varenna Italy, June 9-13 2003. 10 pages, 6 figures, 1 tabl

Extending the Hoyle-State Paradigm to 12 C + 12 C Fusion

Carbon burning is a key step in the evolution of massive stars, Type 1a supernovae and superbursts in x-ray binary systems. Determining the 12C þ 12C fusion cross section at relevant energies by extrapolation of direct measurements is challenging due to resonances at and below the Coulomb barrier. A study of the 24Mgðα; α0Þ24Mg reaction has identified several 0þ states in 24Mg, close to the 12C þ 12C threshold, which predominantly decay to 20Neðground stateÞ þ α. These states were not observed in 20Neðα; α0 Þ20Ne resonance scattering suggesting that they may have a dominant 12C þ 12C cluster structure. Given the very low angular momentum associated with sub-barrier fusion, these states may play a decisive role in 12C þ 12C fusion in analogy to the Hoyle state in helium burning. We present estimates of updated 12C þ 12C fusion reaction rates

Variants Cause Spastic Paraplegia Associated with Cerebral Hypomyelination

Oculodentodigital dysplasia is an autosomal dominant disorder due to variants characterized by dysmorphic features. Neurologic symptoms have been described in some patients but without a clear neuroimaging pattern. To understand the pathophysiology underlying neurologic deficits in oculodentodigital dysplasia, we studied 8 consecutive patients presenting with hereditary spastic paraplegia due to variants. Clinical disease severity was highly variable. Cerebral MR imaging revealed variable white matter abnormalities, consistent with a hypomyelination pattern, and bilateral hypointense signal of the basal ganglia on T2-weighted images and/or magnetic susceptibility sequences, as seen in neurodegeneration with brain iron accumulation diseases. Patients with the more prominent basal ganglia abnormalities were the most disabled ones. This study suggests that -related hereditary spastic paraplegia is a complex neurodegenerative disease affecting both the myelin and the basal ganglia. variants should be considered in patients with hereditary spastic paraplegia presenting with brain hypomyelination, especially if associated with neurodegeneration and a brain iron accumulation pattern

Deformation of the N=Z nucleus 76Sr using beta-decay studies

A novel method of deducing the deformation of the N=Z nucleus 76Sr is presented. It is based on the comparison of the experimental Gamow-Teller strength distribution B(GT) from its beta decay with the results of QRPA calculations. This method confirms previous indications of the strong prolate deformation of this nucleus in a totally independent way. The measurement has been carried out with a large Total Absorption gamma Spectrometer, "Lucrecia", newly installed at CERN-ISOLDE.Comment: Accepted in Phys. Rev. Letter

Constraints on Titan's middle atmosphere ammonia abundance from Herschel/SPIRE sub-millimetre spectra

Sub-millimetre spectra measured with Herschel's SPIRE Fourier Transform Spectrometer were used to search for ammonia (NH3) in Titan's stratosphere. Observations were taken during 2010 and 2011, just after Titan's northern spring equinox, which occurred in mid-2009. In our analysis we used high spectral resolution data (0.074 cm-1 apodised) from the SPIRE shortwave spectrometer array (SSW), which provided the best possible signal-to-noise ratio for detecting any NH3 emission features. These data have the most sensitivity to NH3 spectral emission of any currently available observations, although despite this we did not detect any significant emission features above the noise. However, we can place an improved 3-sigma upper limit on NH3 abundance of <0.19ppb for altitudes 65-110 km (75 km peak sensitivity), or alternatively a column abundance of <1.23×1015molecules/cm2. These observations provide modest constraint for future photochemical models and are consistent with most current stratospheric predictions. Scaling of photochemical model profiles, in order to fit elevated abundances observed at 1100 km by Cassini's INMS instrument, are for the most part also consistent with our observations. © 2012 Elsevier Ltd