6,012 research outputs found
Anatomo-functional correspondence in the superior temporal sulcus
The superior temporal sulcus (STS) is an intriguing region both for its complex anatomy and for the multiple functions that it hosts. Unfortunately, most studies explored either the functional organization or the anatomy of the STS only. Here, we link these two aspects by investigating anatomo-functional correspondences between the voice-sensitive cortex (Temporal Voice Areas) and the STS depth. To do so, anatomical and functional scans of 116 subjects were processed such as to generate individual surface maps on which both depth and functional voice activity can be analyzed. Individual depth profiles of manually drawn STS and functional profiles from a voice localizer (voice > non-voice) maps were extracted and compared to assess anatomo-functional correspondences. Three major results were obtained: first, the STS exhibits a highly significant rightward depth asymmetry in its middle part. Second, there is an anatomo-functional correspondence between the location of the voice-sensitive peak and the deepest point inside this asymmetrical region bilaterally. Finally, we showed that this correspondence was independent of the gender and, using a machine learning approach, that it existed at the individual level. These findings offer new perspectives for the understanding of anatomo-functional correspondences in this complex cortical region
Gregarine species (Apicomplexa) parasitic in the burrowing echinoid <i>Echinocardium cordatum</i>: occurrence and host reaction
Cyclic occurrence of gregarine trophozoites (Apicomplexa) in the burrowing echinoid <i>Echinocardium cordatum</i> (Echinodermata, Spatangoidea)
The occurrence of the gregarine Urospora neapolitana in the spatangoid echinoid Echinocardium cordatum was followed monthly over a 1 yr period. Infesting stages (sporozoites) were seen only in the digestive cells of the hosts' gastric caecum while growing stages (trophozoites) only occurred in the hosts' body cavity. Sporozoites showed no variation in abundance over the investigated period. The number of trophozoites, however, clearly varied with a minimum in summer and early autumn. Trophozoite variation appears to be related to the gonadal cycle of the host
The valuation of clean spread options: linking electricity, emissions and fuels
The purpose of the paper is to present a new pricing method for clean spread options, and to illustrate its main features on a set of numerical examples produced by a dedicated computer code. The novelty of the approach is embedded in the use of a structural model as opposed to reduced-form models which fail to capture properly the fundamental dependencies between the economic factors entering the production process
Dispersion forces in methane
The coefficients of the R-6 and R-7 terms in the series representation of the dispersion interaction between two methane molecules and between methane and helium, neon and argon are calculated by a variation method
Sum rule expressions for bounds on Van der Waals coefficients
We present a simple matrix solution for the moment equations that occur in recently discovered bounds on van der Waals coefficients. Using this matrix solution it is possible to express these new bounds directly in terms of the oscillator strength sum rules of the interacting systems
On the isotropic-liquid crystal phase separation in a solution of rodlike particles of different lengths
The Onsager theory for the isotropic-anisotropic phase separation in a solution of rodlike particles is extended to the case of mixtures of such particles with different lengths. The concentration, composition, order parameters, and orientation dependent thermodynamic quantities of the coexisting phases are calculated for the case of a mixture of rods of two different lengths for different length ratios. It is found that there is a significantly higher mole fraction of the longer rods in the anisotropic phase than in the isotropic phase. The order parameter of the longer rods is higher than in the one component case, whereas the order parameter of the shorter rods first increases and then decreases as the mole fraction of the longer rods is increased. All these features are accentuated as the length ratio of the two kinds of rods increases
Creation of regular arrays of faceted AlN nanostructures via a combined top-down, bottom-up approach
The realisation of spatially-determined, uniform arrays of faceted aluminium nitride (AlN) nanostructures has had limited exploration, largely due to the fact that selective area growth of AlN via MOVPE (Metal Organic Vapour Phase Epitaxy) has not been realised. Instead, this paper reports the use of a combined top-down, bottom-up approach to realise well-faceted, highly-uniform, periodic nanotextured AlN surfaces. MOVPE regrowth is performed upon dry-etched AlN nanorods and nanoholes, and we present a study into the effect of the growth conditions on the resulting faceting and morphology. Specifically, growth temperature, V/III ratio and growth time are investigated and analysed via scanning-electron and atomic-force microscopy. The V/III ratio was found to influence the nanostructure morphology most whilst the growth temperature was found to have much less of an impact within the temperature range studied. Experiments with a longer growth time are performed to create nanostructures for potential use in applications, such as for AlGaN-based quantum-well or quantum-dot emitters
Caveats in transneuronal tracing with unmodified rabies virus: An evaluation of aberrant results using a nearly perfect tracing technique
Apart from the genetically engineered, modified, strains of rabies virus (RABV), unmodified ‘fixed’ virus strains of RABV, such as the ‘French’ subtype of CVS11, are used to examine synaptically connected networks in the brain. This technique has been shown to have all the prerequisite characteristics for ideal tracing as it does not metabolically affect infected neurons within the time span of the experiment, it is transferred transneuronally in one direction only and to all types of neurons presynaptic to the infected neuron, number of transneuronal steps can be precisely controlled by survival time and it is easily detectable with a sensitive technique. Here, using the ‘French’ CVS 11 subtype of RABV in Wistar rats, we show that some of these characteristics may not be as perfect as previously indicated. Using injection of RABV in hind limb muscles, we show that RABV-infected spinal motoneurons may already show lysis 1 or 2 days after infection. Using longer survival times we were able to establish that Purkinje cells may succumb approximately 3 days after infection. In addition, some neurons seem to resist infection, as we noted that the number of RABV-infected inferior olivary neurons did not progress in the same rate as other infected neurons. Furthermore, in our hands, we noted that infection of Purkinje cells did not result in expected transneuronal labeling of cell types that are presynaptic to Purkinje cells such as molecular layer interneurons and granule cells. However, these cell types were readily infected when RABV was injected directly in the cerebellar cortex. Conversely, neurons in the cerebellar nuclei that project to the inferior olive did not take up RABV when this was injected in the inferior olive, whereas these cells could be infected with RABV via a transneuronal route. These results suggest that viral entry from the extracellular space depends on other factors or mechanisms than those used for retrograde transneuronal transfer. We conclude that transneuronal tracing with RABV may result in unexpected results, as not all properties of RABV seem to be ubiquitously valid
Influence of the reactor environment on the selective area thermal etching of GaN nanohole arrays
Selective area thermal etching (SATE) of gallium nitride is a simple subtractive process for creating novel device architectures and improving the structural and optical quality of III-nitride-based devices. In contrast to plasma etching, it allows, for example, the creation of enclosed features with extremely high aspect ratios without introducing ion-related etch damage. We report how SATE can create uniform and organized GaN nanohole arrays from c-plane and (11–22) semi-polar GaN in a conventional MOVPE reactor. The morphology, etching anisotropy and etch depth of the nanoholes were investigated by scanning electron microscopy for a broad range of etching parameters, including the temperature, the pressure, the NH3 flow rate and the carrier gas mixture. The supply of NH3 during SATE plays a crucial role in obtaining a highly anisotropic thermal etching process with the formation of hexagonal non-polar-faceted nanoholes. Changing other parameters affects the formation, or not, of non-polar sidewalls, the uniformity of the nanohole diameter, and the etch rate, which reaches 6 µm per hour. Finally, the paper discusses the SATE mechanism within a MOVPE environment, which can be applied to other mask configurations, such as dots, rings or lines, along with other crystallographic orientations
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