176 research outputs found
Urban energy simulation based on 3d city models: a service-oriented approach
Recent advancements in technology has led to the development of sophisticated software tools revitalizing growth in different domains. Taking advantage of this trend, urban energy domain have developed several compute intensive physical and data driven models. These models are used in various distinct simulation softwares to simulate the whole life-cycle of energy flow in cities from supply, distribution, conversion, storage and consumption. Since some simulation software target a specific energy system, it is necessary to integrate them to predict present and future urban energy needs. However, a key drawback is that, these tools are not compatible with each other as they use custom or propriety formats. Furthermore, they are designed as desktop applications and cannot be easily integrated with third-party tools (open source or commercial). Thereby, missing out on potential model functionalities which are required for sustainable urban energy management. In this paper, we propose a solution based on Service Oriented Architecture (SOA). Our approach relies on open interfaces to offer flexible integration of modelling and computational functionality as loosely coupled distributed services
Effect of Treatment and Cultivar on the Ensiling of Corn Stover
Nine cultivars of corn stover selected for ethanol potential were harvested (34 to 40% dry matter) and each ensiled with six treatments: untreated, lactic acid bacteria, cell-wall degrading enzymes, sulfuric acid, bacteria-enzyme combination and enzyme-acid combination. Ensiling was carried out in vacuum-sealed bags at ~22°C for 60 d. The untreated stovers ensiled well. Lactic acid bacteria and enzyme treatments had no effect on pH, but the bacteria-enzyme combination lowered pH in some cultivars. The acid and acid-enzyme treatments had low pH values ranging from 1.3 to 1.5. Lactic acid was generally highest in the bacteria-enzyme treatment whereas acetic acid was highest for the acid treatments. The acid treatments substantially reduced hemicellulose. Potential ethanol yield on average was highest in the bacteria-enzyme treatments
The ethics of using transgenic non-human primates to study what makes us human
An ongoing flood of comparative genomic data is identifying human lineage specific (HLS) sequences of unknown function, and there is strong interest in investigating their functional effects. Transgenic apes, our closest evolutionary relative, have the highest potential to express HLS sequences as they are expressed in Homo sapiens and likewise experience harm from such transgenic research. These harms render the conduct of this research ethically unacceptable in apes, justifying regulatory barriers between these species and all other non-human primates for transgenic research
Combined and single effects of pesticide carbaryl and toxic Microcystis aeruginosa on the life history of Daphnia pulicaria
The combined influence of a pesticide (carbaryl) and a cyanotoxin (microcystin LR) on the life history of Daphnia pulicaria was investigated. At the beginning of the experiments animals were pulse exposed to carbaryl for 24 h and microcystins were delivered bound in Microcystis’ cells at different, sub-lethal concentrations (chronic exposure). In order to determine the actual carbaryl concentrations in the water LC–MS/MS was used. For analyses of the cyanotoxin concentration in Daphnia’s body enzyme-linked immunosorbent assay (ELISA) was used. Individual daphnids were cultured in a flow-through system under constant light (16 h of light: 8 h of dark), temperature (20°C), and food conditions (Scenedesmus obliquus, 1 mg of C l−1). The results showed that in the treatments with carbaryl egg numbers per female did not differ significantly from controls, but the mortality of newborns increased significantly. Increasing microcystin concentrations significantly delayed maturation, reduced size at first reproduction, number of eggs, and newborns. The interaction between carbaryl and Microcystis was highly significant. Animals matured later and at a smaller size than in controls. The number of eggs per female was reduced as well. Moreover, combined stressors caused frequent premature delivery of offspring with body deformations such as dented carapax or an undeveloped heart. This effect is concluded to be synergistic and could not be predicted from the effects of the single stressors.
Simplicial Complex based Point Correspondence between Images warped onto Manifolds
Recent increase in the availability of warped images projected onto a
manifold (e.g., omnidirectional spherical images), coupled with the success of
higher-order assignment methods, has sparked an interest in the search for
improved higher-order matching algorithms on warped images due to projection.
Although currently, several existing methods "flatten" such 3D images to use
planar graph / hypergraph matching methods, they still suffer from severe
distortions and other undesired artifacts, which result in inaccurate matching.
Alternatively, current planar methods cannot be trivially extended to
effectively match points on images warped onto manifolds. Hence, matching on
these warped images persists as a formidable challenge. In this paper, we pose
the assignment problem as finding a bijective map between two graph induced
simplicial complexes, which are higher-order analogues of graphs. We propose a
constrained quadratic assignment problem (QAP) that matches each p-skeleton of
the simplicial complexes, iterating from the highest to the lowest dimension.
The accuracy and robustness of our approach are illustrated on both synthetic
and real-world spherical / warped (projected) images with known ground-truth
correspondences. We significantly outperform existing state-of-the-art
spherical matching methods on a diverse set of datasets.Comment: Accepted at ECCV 202
Numerical investigations regarding a novel process chain for the production of a hybrid bearing bushing
This contribution deals with the numerical investigations to develop a novel process chain for hybrid solid components using Tailored Forming. For manufacturing a hybrid bearing bushing, co-extrusion is the first step to produce hybrid semi-finished workpieces followed by a die forging process, machining processes and hardening. Combining aluminium with steel, compounds with wear-resistant functional surfaces and reduced weight are realised. Numerical simulations are a decisive part of the process chain design, for example to determine suitable process parameters for the co-extrusion process and to predict the thickness of intermetallic phases in the joining zone using a macroscopic phenomenological model. A numerical design including a tool analysis of the die forging process was carried out taking the experimentally determined material properties and the temperature profile after inductive heating into account. Additionally, the damage and fatigue behaviour of the polycrystalline material of the joining zone are modelled at the microstructure level. Moreover, a new discretization scheme, namely the virtual element method, which is more efficient at grain level, is developed regarding a crystal plasticity framework. Numerical simulations are used to develop inductive heating strategies for the forming process and for the design of the inductive hardening of the functional surface at the end of the process chain. In order to investigate the performance of this hybrid machine element under application-oriented conditions, a contact simulation is linked with a statistical damage model to calculate the bearing fatigue. In this study, a general overview of the individual process steps is given and results of the respective models are presented. © 2020, The Author(s)
Human Health Risk Assessment (HHRA) for environmental development and transfer of antibiotic resistanc
This is the final version of the article. Available from NIEHS via the DOI in this record.Open access journalBACKGROUND: Only recently has the environment been clearly implicated in the risk of antibiotic resistance to clinical outcome, but to date there have been few documented approaches to formally assess these risks. OBJECTIVE: We examined possible approaches and sought to identify research needs to enable human health risk assessments (HHRA) that focus on the role of the environment in the failure of antibiotic treatment caused by antibiotic-resistant pathogens. METHODS: The authors participated in a workshop held 4-8 March 2012 in Québec, Canada, to define the scope and objectives of an environmental assessment of antibiotic-resistance risks to human health. We focused on key elements of environmental-resistance-development "hot spots," exposure assessment (unrelated to food), and dose response to characterize risks that may improve antibiotic-resistance management options. DISCUSSION: Various novel aspects to traditional risk assessments were identified to enable an assessment of environmental antibiotic resistance. These include a) accounting for an added selective pressure on the environmental resistome that, over time, allows for development of antibiotic-resistant bacteria (ARB); b) identifying and describing rates of horizontal gene transfer (HGT) in the relevant environmental "hot spot" compartments; and c) modifying traditional dose-response approaches to address doses of ARB for various health outcomes and pathways. CONCLUSIONS: We propose that environmental aspects of antibiotic-resistance development be included in the processes of any HHRA addressing ARB. Because of limited available data, a multicriteria decision analysis approach would be a useful way to undertake an HHRA of environmental antibiotic resistance that informs risk managers.This manuscript was conceived at a workshop (Antimicrobial Resistance in the Environment: Assessing and Managing Effects of Anthropogenic Activities) held 4–8 March 2012 in Montebello, Québec, Canada. The workshop was sponsored by the Canadian Society of Microbiologists, with financial support from AstraZeneca Ltd.; Pfizer Animal Health; F. Hoffman-La Roche Ltd.; GlaxoSmithKline; Unilever; Huvepharma; the American Cleaning Institute; the Canadian Animal Health Institute; the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety; Health Canada; and the Public Health Agency of Canada
Thermo-electrochemical production of compressed hydrogen from methane with near-zero energy loss
[EN] Conventional production of hydrogen requires large industrial plants to minimize energy losses and capital costs associated with steam reforming, water-gas shift, product separation and compression. Here we present a protonic membrane reformer (PMR) that produces high-purity hydrogen from steam methane reforming in a single-stage process with near-zero energy loss. We use a BaZrO3-based proton-conducting electrolyte deposited as a dense film on a porous Ni composite electrode with dual function as a reforming catalyst. At 800 degrees C, we achieve full methane conversion by removing 99% of the formed hydrogen, which is simultaneously compressed electrochemically up to 50 bar. A thermally balanced operation regime is achieved by coupling several thermo-chemical processes. Modelling of a small-scale (10 kg H-2 day-1) hydrogen plant reveals an overall energy efficiency of >87%. 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