5,154 research outputs found

    Complex Bragg grating writing using direct modulation of the optical fiber with flexural waves

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    A flexural wave is applied to an optical fiber during the process of Bragg grating inscription using the direct writing method through a phase mask. Using this approach, we can dither the writing process to allow complex grating writing. Examples we demonstrate are tunable sampled gratings and phase-shifted gratings. © 2011 American Institute of Physics

    Dominant takeover regimes for genetic algorithms

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    The genetic algorithm (GA) is a machine-based optimization routine which connects evolutionary learning to natural genetic laws. The present work addresses the problem of obtaining the dominant takeover regimes in the GA dynamics. Estimated GA run times are computed for slow and fast convergence in the limits of high and low fitness ratios. Using Euler's device for obtaining partial sums in closed forms, the result relaxes the previously held requirements for long time limits. Analytical solution reveal that appropriately accelerated regimes can mark the ascendancy of the most fit solution. In virtually all cases, the weak (logarithmic) dependence of convergence time on problem size demonstrates the potential for the GA to solve large N-P complete problems

    The impact of COVID-19 on anaesthesia and critical care services in the UK: a serial service evaluation

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    Between October 2020 and January 2021, we conducted three national surveys to track anaesthetic, surgical and critical care activity during the second COVID-19 pandemic wave in the UK. We surveyed all NHS hospitals where surgery is undertaken. Response rates, by round, were 64%, 56% and 51%. Despite important regional variations, the surveys showed increasing systemic pressure on anaesthetic and peri-operative services due to the need to support critical care pandemic demands. During Rounds 1 and 2, approximately one in eight anaesthetic staff were not available for anaesthetic work. Approximately one in five operating theatres were closed and activity fell in those that were open. Some mitigation was achieved by relocation of surgical activity to other locations. Approximately one-quarter of all surgical activity was lost, with paediatric and non-cancer surgery most impacted. During January 2021, the system was largely overwhelmed. Almost one-third of anaesthesia staff were unavailable, 42% of operating theatres were closed, national surgical activity reduced to less than half, including reduced cancer and emergency surgery. Redeployed anaesthesia staff increased the critical care workforce by 125%. Three-quarters of critical care units were so expanded that planned surgery could not be safely resumed. At all times, the greatest resource limitation was staff. Due to lower response rates from the most pressed regions and hospitals, these results may underestimate the true impact. These findings have important implications for understanding what has happened during the COVID-19 pandemic, planning recovery and building a system that will better respond to future waves or new epidemics

    Investigations on the Peach 4 Debrite, a Late Pleistocene Mass Movement on the Northwest British Continental Margin

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    The Peach 4 debrite is the most recent in a series of large scale Pleistocene MTDs within the Barra fan on the northwest British continental margin. Geophysical data indicate that Peach 4 was formed through a combination of blocky and muddy debris flows and affects an area of ~ 700 km2. BGS core sample 56 -10 36, located directly over the Peach 4 debrite, provides a minimum age of 14.68 ka cal BP for the last major failure. An upwards fining turbidite sequence in BGS core sample 56 -10 239 is associ-ated with increased As and S concentrations, indicators of diagenetic pyrite which forms under anoxic conditions. It is proposed that As and S concentrations may pro-vide a method of distinguishing between contourite and turbidite sedimentation, though further research is required

    Foot kinematics in patients with two patterns of pathological plantar hyperkeratosis

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    Background: The Root paradigm of foot function continues to underpin the majority of clinical foot biomechanics practice and foot orthotic therapy. There are great number of assumptions in this popular paradigm, most of which have not been thoroughly tested. One component supposes that patterns of plantar pressure and associated hyperkeratosis lesions should be associated with distinct rearfoot, mid foot, first metatarsal and hallux kinematic patterns. Our aim was to investigate the extent to which this was true. Methods: Twenty-seven subjects with planter pathological hyperkeratosis were recruited into one of two groups. Group 1 displayed pathological plantar hyperkeratosis only under metatarsal heads 2, 3 and 4 (n = 14). Group 2 displayed pathological plantar hyperkeratosis only under the 1st and 5th metatarsal heads (n = 13). Foot kinematics were measured using reflective markers on the leg, heel, midfoot, first metatarsal and hallux. Results: The kinematic data failed to identify distinct differences between these two groups of subjects, however there were several subtle (generally <3°) differences in kinematic data between these groups. Group 1 displayed a less everted heel, a less abducted heel and a more plantarflexed heel compared to group 2, which is contrary to the Root paradigm. Conclusions: There was some evidence of small differences between planter pathological hyperkeratosis groups. Nevertheless, there was too much similarity between the kinematic data displayed in each group to classify them as distinct foot types as the current clinical paradigm proposes

    Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in England (CHASE): a cross-sectional analysis.

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    BACKGROUND: Regular breakfast consumption may protect against type 2 diabetes risk in adults but little is known about its influence on type 2 diabetes risk markers in children. We investigated the associations between breakfast consumption (frequency and content) and risk markers for type 2 diabetes (particularly insulin resistance and glycaemia) and cardiovascular disease in children. METHODS AND FINDINGS: We conducted a cross-sectional study of 4,116 UK primary school children aged 9-10 years. Participants provided information on breakfast frequency, had measurements of body composition, and gave fasting blood samples for measurements of blood lipids, insulin, glucose, and glycated haemoglobin (HbA1c). A subgroup of 2,004 children also completed a 24-hour dietary recall. Among 4,116 children studied, 3,056 (74%) ate breakfast daily, 450 (11%) most days, 372 (9%) some days, and 238 (6%) not usually. Graded associations between breakfast frequency and risk markers were observed; children who reported not usually having breakfast had higher fasting insulin (percent difference 26.4%, 95% CI 16.6%-37.0%), insulin resistance (percent difference 26.7%, 95% CI 17.0%-37.2%), HbA1c (percent difference 1.2%, 95% CI 0.4%-2.0%), glucose (percent difference 1.0%, 95% CI 0.0%-2.0%), and urate (percent difference 6%, 95% CI 3%-10%) than those who reported having breakfast daily; these differences were little affected by adjustment for adiposity, socioeconomic status, and physical activity levels. When the higher levels of triglyceride, systolic blood pressure, and C-reactive protein for those who usually did not eat breakfast relative to those who ate breakfast daily were adjusted for adiposity, the differences were no longer significant. Children eating a high fibre cereal breakfast had lower insulin resistance than those eating other breakfast types (p for heterogeneity <0.01). Differences in nutrient intakes between breakfast frequency groups did not account for the differences in type 2 diabetes markers. CONCLUSIONS: Children who ate breakfast daily, particularly a high fibre cereal breakfast, had a more favourable type 2 diabetes risk profile. Trials are needed to quantify the protective effect of breakfast on emerging type 2 diabetes risk. Please see later in the article for the Editors' Summary

    Linear scleroderma as a rare cause of enophthalmos: a case report

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    © 2007 Fernando et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

    Pull-out and push-in tests of bonded steel strands

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    Martí Vargas, JR. (2013). Pull-out and push-in tests of bonded steel strands. Magazine of Concrete Research. 65(18):1128-1131. doi:10.1680/macr.13.00061S112811316518Balázs LG .Bond Model with Non-Linear Bond-Slip Law, 1987, Politecnico di Milano, Italy, 395–430, Studi e Ricerche, Post-Graduate Course for Reinforced Concrete Structures, V.8/86.Balazs, G. L. (1992). Transfer Control of Prestressing Strands. PCI Journal, 37(6), 60-71. doi:10.15554/pcij.11011992.60.71Balazs, G. L. (1993). Transfer Length of Prestressing Strand as a Function of Draw-In and Initial Prestress. PCI Journal, 38(2), 86-93. doi:10.15554/pcij.03011993.86.93Balázs, G. L. (2007). Connecting Reinforcement to Concrete by Bond. Beton- und Stahlbetonbau, 102(S1), 46-50. doi:10.1002/best.200710109Carmo RNF .Ancoragem de Armaduras Pré-Esforçadas por Pré-Tensão. MSc thesis, 1999, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, Portugal, (in Portuguese).Faria, D. M. V., Lúcio, V. J. G., & Pinho Ramos, A. (2011). Pull-out and push-in tests of bonded steel strands. Magazine of Concrete Research, 63(9), 689-705. doi:10.1680/macr.2011.63.9.689Faria, D. M. V., Lúcio, V. J. G., & Ramos, A. P. (2011). Strengthening of flat slabs with post-tensioning using anchorages by bonding. Engineering Structures, 33(6), 2025-2043. doi:10.1016/j.engstruct.2011.02.039Faria, D. M. V., Lúcio, V. J. G., & Pinho Ramos, A. (2012). Post-punching behaviour of flat slabs strengthened with a new technique using post-tensioning. Engineering Structures, 40, 383-397. doi:10.1016/j.engstruct.2012.03.014Laldji S .Bond Characteristics of Prestressing Strand in Grout. MPhil thesis, 1987, University of Leicester, UK.Laldji, S., & Young, A. G. (1988). Bond between steel strand and cement grout in ground anchorages. Magazine of Concrete Research, 40(143), 90-98. doi:10.1680/macr.1988.40.143.90Lopes, S. M. R., & do Carmo, R. N. F. (2002). Bond of prestressed strands to concrete: transfer rate and relationship between transmission length and tendon draw-in. Structural Concrete, 3(3), 117-126. doi:10.1680/stco.2002.3.3.117Martí-Vargas, J. R., Serna-Ros, P., Fernández-Prada, M. A., Miguel-Sosa, P. F., & Arbeláez, C. A. (2006). Test method for determination of the transmission and anchorage lengths in prestressed reinforcement. Magazine of Concrete Research, 58(1), 21-29. doi:10.1680/macr.2006.58.1.21Marti-Vargas, J. R., Arbelaez, C. A., Serna-Ros, P., Navarro-Gregori, J., & Pallares-Rubio, L. (2007). Analytical model for transfer length prediction of 13 mm prestressing strand. Structural Engineering and Mechanics, 26(2), 211-229. doi:10.12989/sem.2007.26.2.211Palmer, K. D., & Schultz, A. E. (2011). Experimental investigation of the web-shear strength of deep hollow-core units. PCI Journal, 56(4), 83-104. doi:10.15554/pcij.09012011.83.10
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