1,671 research outputs found

    Gibberellic acid, chlorocholine chloride and yield increases in Zante currant

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    GA and CCC additively increased yield of Zante currant fruit. GA induced an increase in berry size (weight and volume) which was unaffected by CCC, while CCC offset to an appreciable extent the reduction in berry number associated with low concentrations of GA

    Effect of emergency department fast track on emergency department length of stay : a case-control study

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    Objective: To examine the effect of fast track on emergency department (ED) length of stay (LOS).Design and setting: Pair-matched case&ndash;control design in a public teaching hospital in metropolitan Melbourne, Australia.Participants: Patients treated by the ED fast track (cases) between 1 January and 31 March 2007 were compared with patients treated by the usual ED processes (controls) from 1 July to 15 November 2006 (n = 822 matched pairs).Intervention: ED fast track was established in November 2006 and focused on the management of patients with non-urgent complaints.Main outcome measures: The primary outcome measure was ED LOS for fast-track patients. Secondary outcomes were waiting times and ED LOS for other ED patients.Results: Median ED LOS for non-admitted patients was 132 minutes (interquartile range (IQR) 83&ndash;205.25) for controls and 116 minutes (IQR 75.5&ndash;159.0) for cases (p&lt;0.01). Fast-track patients had a significantly higher incidence of discharge within 2 h (53% vs 44%, p&lt;0.01) and 4 h (92% vs 84%, p&lt;0.01).Conclusions: ED fast track decreased ED LOS for non-admitted patients without compromising waiting times and ED LOS for other ED patients<br /

    Mastication of Nuts under Realistic Eating Conditions: Implications for Energy Balance

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    The low digestibility and high satiety effects of nuts have been partly attributed to mastication. This work examines chewing forces and the bolus particle size of nuts (walnuts, almonds, pistachios) varying in physical properties under different conditions (with and without water, juice, sweetened yogurt and plain yogurt) along with satiety sensations and gut hormone concentrations following walnut consumption (whole or butter). In a randomized, cross-over design with 50 adults (25 males, 25 females; Body Mass Index (BMI) 24.7 ± 3.4 kg/m²; age: 18⁻52 years old (y/o), the chewing forces and particle size distribution of chewed nuts were measured under different chewing conditions. Appetite sensations were measured at regular intervals for 3 h after nut intake, and plasma samples were collected for the measurement of glucose, insulin and Glucagon-like peptide-1 (GLP-1). The three nuts displayed different particle sizes at swallowing though no differences in chewing forces were observed. Walnuts with yogurt yielded larger particle sizes than the other treatments. Particle size was not correlated with either food palatability or flavor. Fullness sensations were higher after whole nut than nut butter consumption though there were no significant changes in glucose, insulin, or GLP-1 concentrations under any condition. Changing the conditions at swallowing might influence the release of energy from nuts

    Acute and second-meal effects of almond form in impaired glucose tolerant adults: a randomized crossover trial

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    <p>Abstract</p> <p>Background</p> <p>Nut consumption may reduce the risk of developing type 2 diabetes. The aim of the current study was to measure the acute and second-meal effects of morning almond consumption and determine the contribution of different nut fractions.</p> <p>Methods</p> <p>Fourteen impaired glucose tolerant (IGT) adults participated in a randomized, 5-arm, crossover design study where whole almonds (WA), almond butter (AB), defatted almond flour (AF), almond oil (AO) or no almonds (vehicle - V) were incorporated into a 75 g available carbohydrate-matched breakfast meal. Postprandial concentrations of blood glucose, insulin, non-esterified free fatty acids (NEFA), glucagon-like peptide-1 (GLP-1) and appetitive sensations were assessed after treatment breakfasts and a standard lunch.</p> <p>Results</p> <p>WA significantly attenuated second-meal and daylong blood glucose incremental area under the curve (AUCI) and provided the greatest daylong feeling of fullness. AB and AO decreased blood glucose AUCI in the morning period and daylong blood glucose AUCI was attenuated with AO. WA and AO elicited a greater second-meal insulin response, particularly in the early postprandial phase, and concurrently suppressed the second-meal NEFA response. GLP-1 concentrations did not vary significantly between treatments.</p> <p>Conclusions</p> <p>Inclusion of almonds in the breakfast meal decreased blood glucose concentrations and increased satiety both acutely and after a second-meal in adults with IGT. The lipid component of almonds is likely responsible for the immediate post-ingestive response, although it cannot explain the differential second-meal response to AB versus WA and AO.</p

    Hepatocyte growth factor regulates neovascularization in developing fat pads

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    In this study, we used lentiviral-delivered shRNA to generate a clonal line of 3T3-F442A preadipocytes with stable silencing of hepatocyte growth factor (HGF) expression and examined the long-term consequence of this modification on fat pad development. HGF mRNA expression was reduced 94%, and HGF secretion 79% (P < 0.01), compared with preadipocytes treated with nontargeting shRNA. Fat pads derived from HGF knockdown preadipocytes were significantly smaller (P < 0.01) than control pads beginning at 3 days postinjection (0.022 ± 0.003 vs. 0.037 ± 0.004 g), and further decreased in size at day 7 (0.015 ± 0.004 vs. 0.037 ± 0.003 g) and day 14 (0.008 ± 0.002 vs. 0.045 ± 0.007 g). Expression of the endothelial cell genes TIE1 and PECAM1 increased over time in control fat pads (1.6 ± 0.4 vs. 11.4 ± 1.7 relative units at day 3 and 14, respectively; P < 0.05) but not in HGF knockdown fat pads (1.1 ± 0.5 vs. 5.9 ± 2.2 relative units at day 3 and 14). Contiguous vascular structures were observed in control fat pads but were much less developed in HGF knockdown fat pads. Differentiation of preadipocytes to mature adipocytes was significantly attenuated in HGF knockdown fat pads. Fat pads derived from preadipocytes with knockdown of the HGF receptor c-MET were smaller than control pads at day 3 postinjection (0.034 ± 0.002 vs. 0.049 ± 0.004 g; P < 0.05), and remained the same size through day 14. c-MET knockdown fat pads developed a robust vasculature, and preadipocytes differentiated to mature adipocytes. Overall these data suggest that preadipocyte-secreted HGF is an important regulator of neovascularization in developing fat pads

    Planck scale still safe from stellar images

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    The recent paper of Lieu and Hillman [1] that a possible, (birefringence like) phase difference ambiguity coming from Planck effects would alter stellar images of distant sources is questioned. Instead for {\em division of wavefront} interference and diffraction phenomena, initial (lateral) coherence is developed simply by propagation of rays (cf. van Cittert-Zernike theorem). This case is strongly immune to quantum gravity influences that could tend to reduce phase coherence. The phase ambiguity, if actually present, could reduce any underlying polarization of the light rays.Comment: final version for CQ

    Optimizing Heat Alert Issuance with Reinforcement Learning

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    A key strategy in societal adaptation to climate change is the use of alert systems to reduce the adverse health impacts of extreme heat events by prompting preventative action. In this work, we investigate reinforcement learning (RL) as a tool to optimize the effectiveness of such systems. Our contributions are threefold. First, we introduce a novel RL environment enabling the evaluation of the effectiveness of heat alert policies to reduce heat-related hospitalizations. The rewards model is trained from a comprehensive dataset of historical weather, Medicare health records, and socioeconomic/geographic features. We use variational Bayesian techniques to address low-signal effects and spatial heterogeneity, which are commonly encountered in climate & health settings. The transition model incorporates real historical weather patterns enriched by a data augmentation mechanism based on climate region similarity. Second, we use this environment to evaluate standard RL algorithms in the context of heat alert issuance. Our analysis shows that policy constraints are needed to improve the initially poor performance of RL. Lastly, a post hoc contrastive analysis provides insight into scenarios where our modified heat alert-RL policies yield significant gains/losses over the current National Weather Service alert policy in the United States.Comment: Main text has 21 pages with 3 tables and 7 figure

    Learning in Informal Environments Through Engineering Activities Through the Partnership with the Girl Scouts

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    More affordable and portable robots have enabled easier access for outreach activities to happen in different environments. However, exposure to robotics often relies on seeing robots in action, such as industrial robotics and robots that are used for research purposes. Old Dominion University’s College of Engineering and Technology in Norfolk, Virginia recently signed a partnership agreement with the Girl Scouts of Colonial Coast as one of the focused outreach strategies that target the female population. Various events are held on campus in the Hampton Roads residential area located in the southeastern United States, which has a population of around 2 million people. Through this method, elementary age girls can be exposed to engineering content by attending events that are held on the university campus and lead by faculty along with graduate and undergraduate students. This paper showcases one such learning activity through an informal setting activity designed for the K-5 elementary grade levels. In this case, Girl Scouts in the following groups: Daisies, Brownies, and Juniors. Similar activities can be delivered on any other college campus that offers majors related to the area of mechanical engineering / mechanical engineering technology; civil engineering / civil engineering technology; and electrical engineering / electrical engineering technology
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