Prospects for Uganda's Dairy Industry

The East African country of Uganda might not be thought of as the location of a viable, growing dairy industry. However, Uganda recorded a threefold increase in milk production from 1991 to 2004. While Uganda's dairy industry faces important challenges, the industry possesses advantages that can lead to further increases in milk production if additional, profitable markets can be found for Uganda's milk and dairy products. A major advantage possessed by Uganda's dairy industry is a favorable climate for milk production. Uganda's farmers also have demonstrated a willingness to accept new technologies that can increase milk production. The biggest challenges facing the industry are those associated with poor milk quality and pronounced seasonality of milk production.Uganda Dairy Industry, Uganda's Political and Economic Environment, Pasture-Based Dairy Industry, Poor Milk Quality, Agribusiness, Crop Production/Industries, Farm Management, Food Consumption/Nutrition/Food Safety, Industrial Organization, International Development, International Relations/Trade, Land Economics/Use, Political Economy, Public Economics,

Liquid rocket performance computer model with distributed energy release Interim final report, 15 Aug. 1969 - 15 Aug. 1970

Liquid propellant rocket engine performance computer program with distributed energy releas

Carefull Ethos: The Construction of Ethos in Dorothy Leigh\u27s The Mothers Blessing

As one of the most popular conduct manuals in the early seventeenth century, Dorothy Leigh\u27s The Mothers Blessing is often categorized as private, domestic literature. In this dissertation, I examine the strategies Leigh employed to create ethos, and I argue that her strategic depiction of herself as a fearefull, faithfull, carefull mother helped her authorize herself as a public figure. Specifically, I investigate the strategies Leigh employed to create a persuasive ethos within the genre of the conduct manual. Through mother-based ethos strategies, Leigh presented herself deliberately, augmenting her authority as Mother and positioning her work within a male-dominated print culture that demanded silence, obedience, and chastity of women. Leigh uses Mother rhetorically to carve out her place as a confident woman and to position herself as the Mother, who the conduct manual into a place for public discourse. I position Dorothy Leigh\u27s The Mothers Blessing in the context of several seventeenth-century political, social, and religious debates, and I argue that Leigh should be seen as a public figure whose career was eminently rhetorical

Effect of Cooking Method on Meat Texture in Normal and Woody Broiler Breast Fillets Using Instrumental Analysis and Descriptive Sensory Analysis

Over the past few decades, broiler breast meat has changed in terms of meat quality. Meat quality has deteriorated with the rise in the occurrence of muscle myopathies. Conditions such as woody breast, which is described as pale and bulging areas of distinct hardness, compromise both the textural and technological traits that have been associated with breast meat. The Meullenet-Owens Razor Shear (MORS) method is a common method for indirectly assessing poultry meat tenderness. A blunt version of the MORS (BMORS) has been shown to be a more sensitive method at higher degrees of toughness. A slightly larger stainless steel incisor blunt blade (IMORS) may offer probe longevity and may also be useful in assessing tough meat with or without WB characteristics. Instrumental analysis was conducted on 56 or 60 d broilers that were processed and scored for woody breast (WB). Individual fillets were separated into right and left fillets and the right fillet and cooked using three different heating methods: bake, grill, or sous vide and were used to measure meat quality attributes such as cook loss, MORS force (MORSF), BMORS force (BMORSF), IMORS force (IMORS), MORS energy (MORSE), BMORS energy (BMORSE), IMORS energy (IMORSE) and peak counts of the shear curves (PC-MORS, PC-BMORS and PC-IMORS). IMORS shear values are higher (P\u3c0.05) than both MORS and BMORS. Cook loss was higher (P\u3c0.001) in severe woody breast fillets than normal fillets regardless of cook method. In the descriptive sensory analysis, trained panelists (n=9) evaluated normal (NORM) and severe (SEV) left fillets from the 56 d broilers used in instrumental analysis. SEV fillets had a higher score (P\u3c0.05) for crunchiness than NORM fillets. SEV fillets cooked sous vide retained more moisture (P\u3c0.001) than SEV fillets that were grilled or baked. Results from the instrumental analysis suggest that IMORS may offer a higher sensitivity for tenderness and textural changes related to WB and that peak counts may offer a visual measure of textural differences related to WB. Descriptive sensory analysis results suggest that certain descriptive attributes are related to WB and that the sous vide cook method may offer improvements of the textual qualities of WB

Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: The CINDERELLA trial

<p>Abstract</p> <p>Background</p> <p>Treatment of patients with recurrent glioma includes neurosurgical resection, chemotherapy, or radiation therapy. In most cases, a full course of radiotherapy has been applied after primary diagnosis, therefore application of re-irradiation has to be applied cauteously. With modern precision photon techniques such as fractionated stereotactic radiotherapy (FSRT), a second course of radiotherapy is safe and effective and leads to survival times of 22, 16 and 8 months for recurrent WHO grade II, III and IV gliomas.</p> <p>Carbon ions offer physical and biological characteristics. Due to their inverted dose profile and the high local dose deposition within the Bragg peak precise dose application and sparing of normal tissue is possible. Moreover, in comparison to photons, carbon ions offer an increased relative biological effectiveness (RBE), which can be calculated between 2 and 5 depending on the GBM cell line as well as the endpoint analyzed. Protons, however, offer an RBE which is comparable to photons.</p> <p>First Japanese Data on the evaluation of carbon ion radiation therapy for the treatment of primary high-grade gliomas showed promising results in a small and heterogeneous patient collective.</p> <p>Methods Design</p> <p>In the current Phase I/II-CINDERELLA-trial re-irradiation using carbon ions will be compared to FSRT applied to the area of contrast enhancement representing high-grade tumor areas in patients with recurrent gliomas. Within the Phase I Part of the trial, the Recommended Dose (RD) of carbon ion radiotherapy will be determined in a dose escalation scheme. In the subsequent randomized Phase II part, the RD will be evaluated in the experimental arm, compared to the standard arm, FSRT with a total dose of 36 Gy in single doses of 2 Gy.</p> <p>Primary endpoint of the Phase I part is toxicity. Primary endpoint of the randomized part II is survival after re-irradiation at 12 months, secondary endpoint is progression-free survival.</p> <p>Discussion</p> <p>The Cinderella trial is the first study to evaluate carbon ion radiotherapy for recurrent gliomas, and to compare this treatment to photon FSRT in a randomized setting using an ion beam delivered by intensity modulated rasterscanning.</p> <p>Trial Registration</p> <p>NCT01166308</p

Collaborative Course Design in Scientific Writing: Experimentation and Productive Failure

English 3820: Scientific Writing, a writing-intensive (WI) course offered by the Department of English at East Carolina University (ECU), serves primarily science majors. According to the course catalog, it provides students with “practice in assimilation and written presentation of scientific information.� The course asks students to consider the situated nature of scientific writing and also to produce scientific writing for various audiences. Throughout the course, students examine theories, methodologies, and ideologies that undergird scientific writing with an eye to perfecting both critique and imitation of scientific styles

Configuration development study of the X-24C hypersonic research airplane

Bottom line results were made of a three-phase study to determine the feasibility of designing, building, and operating, and maintaining an air-launched high performance aircraft capable of cruising at speeds up to Mach 8 for short durations. The results show that Lockalloy heat-sink structure affords the capability for a 'work-horse' vehicle which can serve as an excellent platform for this research. It was further concluded that the performance of a blended wing body configuration surpassed that of a lifting body design for typical X-24C missions. The cost of a two vehicle program, less engines, B-52 modification and contractor support after delivery, can be kept within $70M (in Jan. 1976 dollars)

Characterization of the Oscillometric Method for Measuring Indirect Blood Pressure

In this study, human subjects and dogs were used to determine the ability of the oscillometric method to indicate systolic and diastolic pressure. In the human studies, the auscultatory method was used as the reference. In the animal studies, directly recorded blood pressure was used as the reference. The ability of the sudden increase in cuff pressure oscillations during cuff deflation to indicate systolic pressure was examined and found to overestimate systolic pressure slightly in man, but more in animals. Systolic pressure was encountered when the cuff pressure oscillations were about one half of their maximum amplitude. However, in both man and animals the ratio was not constant; although the range was less in man than in animals. Diastolic pressure was encountered when cuff pressure oscillation amplitude was about 0.8 of the maximal amplitude. This ratio for diastolic pressure was not constant over a range of diastolic pressure. The range of variability was less for man than for the dog

Importance of Considering Rate of Passage When Determining Energy Content of Forages for High Producing Animals

The objective of this study was to determine the effect of higher rates of passage and correspondingly lower rumen retention times on digestion of forages. One hundred and fifty samples of legumes, grasses and grass-legume mixtures were collected from farmer samples submitted to commercial forage testing laboratories and 32 samples of alfalfa at varying maturity were collected from research plots. In vitro digestions were performed for either 24 or 48 hours followed by neutral detergent analysis. Neither acid detergent fiber (ADF) nor neutral detergent fiber (NDF) predicted the standard 48-hour digestion very well (r2 = -0.38 and B0.26, respectively). Similar results were noted for 24-hour digestion (r2 = -0.48 and B0.47, respectively). While the correlation was high between 24- and 48-hour digestions (r2 = 0.86), individual samples showed considerable variation. It is recommended that digestion kinetics be considered with determining energy availability for forages for higher producing animals

NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer\u27s Disease

Alzheimer’s disease (AD) brains are characterized by fibrillar amyloid-β (Aβ) peptide containing plaques and associated reactive microglia. The proinflammatory phenotype of the microglia suggests that they may negatively affect disease course and contribute to behavioral decline. This hypothesis predicts that attenuating microglial activation may provide benefit against disease. Prior work from our laboratory and others has characterized a role for the transcription factor, nuclear factor of activated T cells (NFAT), in regulating microglial phenotype in response to different stimuli, including Aβ peptide. We observed that the NFATc2 isoform was the most highly expressed in murine microglia cultures, and inhibition or deletion of NFATc2 was sufficient to attenuate the ability of the microglia to secrete cytokines. In order to determine whether the NFATc2 isoform, in particular, was a valid immunomodulatory target in vivo, we crossed an NFATc2–/– line to a well-known AD mouse model, an AβPP/PS1 mouse line. As expected, the AβPP/PS1 x NFATc2–/– mice had attenuated cytokine levels compared to AβPP/PS1 mice as well as reduced microgliosis and astrogliosis with no effect on plaque load. Although some species differences in relative isoform expression may exist between murine and human microglia, it appears that microglial NFAT activity is a viable target for modulating the proinflammatory changes that occur during AD