108 research outputs found
Producing forage crop seeds for organic agriculture: evolving techniques
This tool is a data sheet that can be used by French farmers who produce or want to produce forage crops seeds in organic conditions.
It provides advice starting from the contract signing to the seed drying, going through the specificities of the crop, the sowing, irrigation, specific pests and their management, and the harvest
Producing zucchini seeds for organic agriculture
This tool is a data sheet that can be used by French farmers who produce or want to produce zucchini seeds in organic conditions.
It provides advices starting from the contract signing to the seed drying, going through the specificities of the crop, the sowing, irrigation, specific pests and their management, and the harvest
Long-term results and GvHD after prophylactic and preemptive donor lymphocyte infusion after allogeneic stem cell transplantation for acute leukemia
We report on 318 patients with acute leukemia, receiving donor lymphocyte infusion (DLI) in complete hematologic remission (CHR) after allogeneic stem cell transplantation (alloSCT). DLI were applied preemptively (preDLI) for minimal residual disease (MRD, n = 23) or mixed chimerism (MC, n = 169), or as prophylaxis in high-risk patients with complete chimerism and molecular remission (proDLI, n = 126). Median interval from alloSCT to DLI1 was 176 days, median follow-up was 7.0 years. Five-year cumulative relapse incidence (CRI), non-relapse mortality (NRM), leukemia-free and overall survival (LFS/OS) of the entire cohort were 29.1%, 12.7%, 58.2%, and 64.3%. Cumulative incidences of acute graft-versus-host disease (aGvHD) grade II–IV°/chronic GvHD were 11.9%/31%. Nineteen patients (6%) died from DLI-induced GvHD. Age ≥60 years (p = 0.046), advanced stage at transplantation (p = 0.003), shorter interval from transplantation (p = 0.018), and prior aGvHD ≥II° (p = 0.036) were risk factors for DLI-induced GvHD. GvHD did not influence CRI, but was associated with NRM and lower LFS/OS. Efficacy of preDLI was demonstrated by decreasing MRD/increasing blood counts in 71%, and increasing chimerism in 70%. Five-year OS after preDLI for MRD/MC was 51%/68% among responders, and 37% among non-responders. The study describes response and outcome of DLI in CHR and helps to identify candidates without increased risk of severe GvHD
An eV-scale sterile neutrino search using eight years of atmospheric muon neutrino data from the IceCube Neutrino Observatory
The results of a 3+1 sterile neutrino search using eight years of data from
the IceCube Neutrino Observatory are presented. A total of 305,735 muon
neutrino events are analyzed in reconstructed energy-zenith space to test for
signatures of a matter-enhanced oscillation that would occur given a sterile
neutrino state with a mass-squared differences between 0.01\,eV and
100\,eV. The best-fit point is found to be at
and , which is consistent with the no sterile
neutrino hypothesis with a p-value of 8.0\%.Comment: 11 pages, 5 figures. This letter is supported by the long-form paper
"Searching for eV-scale sterile neutrinos with eight years of atmospheric
neutrinos at the IceCube neutrino telescope," also appearing on arXiv.
Digital data release available at:
https://github.com/icecube/HE-Sterile-8year-data-releas
Searching for eV-scale sterile neutrinos with eight years of atmospheric neutrinos at the IceCube neutrino telescope
We report in detail on searches for eV-scale sterile neutrinos, in the
context of a 3+1 model, using eight years of data from the IceCube neutrino
telescope. By analyzing the reconstructed energies and zenith angles of 305,735
atmospheric and events we construct confidence
intervals in two analysis spaces: vs.
under the conservative assumption ; and
vs. given sufficiently large that
fast oscillation features are unresolvable. Detailed discussions of the event
selection, systematic uncertainties, and fitting procedures are presented. No
strong evidence for sterile neutrinos is found, and the best-fit likelihood is
consistent with the no sterile neutrino hypothesis with a p-value of 8\% in the
first analysis space and 19\% in the second.Comment: This long-form paper is a companion to the letter "An eV-scale
sterile neutrino search using eight years of atmospheric muon neutrino data
from the IceCube Neutrino Observatory". v2: update other experiments contours
on results plo
Paper Trails: Following the Money
In many recent elections, the candidates who raise the most money have a better shot at winning, so candidates must raise millions of dollars to win an election. A top question to consider in all elections: Where is the money coming from?
Posting about the financing behind federal elections from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.
http://inallthings.org/paper-trails-following-the-money
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
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