(Un)conventional coupling: Interracial sex and intimacy in contemporary neo-slave narratives

(Un)Conventional Coupling initiates a more expansive critical conversation on the contemporary neo-slave narrative. The dissertation\u27s central argument is that authors of neo-slave narratives rely on the politicized theme of interracial coupling to both reimagine history and explore the possibility of social transformation. to establish a framework for my particular focus on interracial intimacy, this study extends the boundaries of the genre by adopting Paul Gilroy\u27s theory of the black Atlantic. This theoretical paradigm serves as a provisional framework for both accommodating and analyzing the complexity of authorship, nationality, and influence within this large body of work.;This dissertation interprets neo-slave narratives\u27 preoccupation with interracial sex and intimacy as a compelling reason to situate the critical analysis of the genre within a more expansive context. The prevalence of discourses and representations of interracial desire, sexuality, and intimacy within the genre reveals a preoccupation with cross-cultural connection. Additionally, authors of neo-slave narratives rely on black-white coupling to explore the concepts and realities of race. Indeed, interracial intimacy provides an effective mechanism for this literature to invigorate a dialogue about race and why it still matters in the twenty-first century.;Adopting the term (un)conventional coupling to destabilize racialized ideologies of sexuality and desire, this project reads black-white coupling as a trope that represents a complex and conflicted sense of transracial intimacy in these novels. This study analyzes the representation of transracial intimacy in three different novels: Sherley Anne Williams\u27 Dessa Rose, David Bradley\u27s The Chaneysville Incident, and Valerie Martin\u27s Property. Each chapter demonstrates the different ways in which these authors rely on the trope of black-white coupling to construct the double-edged critique of black Atlantic political culture. First, this trope exposes a hidden history in order to reveal a more comprehensive and nuanced version of slavery and its myriad legacies. Secondly, representations of interracial intimacy allow authors to posit utopian possibilities out of relations of difference by creating a space for transformative acts of social reinvention

Junior Recital:Colleen Doyle, Viola

Kemp Recital Hall Sunday Evening March 25, 2007 7:00p.m

Senior Recital:Colleen Doyle, Viola

Kemp Recital Hall Saturday Evening April 19, 2008 7:00p.m

Signs of progress in the Australian post-2000 COPD experience, but some old problems remain

This study aims to describe current trends in Australia regarding chronic obstructive pulmonary disease (COPD) mortality and morbidity rates, and in its treatment and prevention from 2000 to 2010. The study’s purpose is to better define future directions in curbing COPD. People with COPD and their caregivers who attend patient support groups (n = 21), pulmonary rehabilitation group coordinators (n = 27) within Victoria, and the Australian Lung Foundation provided informed feedback. COPD was a leading underlying cause of death in both sexes during these years. Nevertheless, mortality rates declined from 1980 to 2007, with rates for males almost halving. Its prevalence has also substantially declined. Smoking rates have declined in age groups over 40 years old in both sexes. The COPD-X Plan provides evidence-based guidelines for the management of COPD. Many government, professional, and community initiatives have been recently implemented to promote the Plan. Two studies—one conducted before and one conducted after the publication of the COPD-X Plan—report some progress, but there are still very considerable departures from evidence-based practice. The Australian Lung Foundation estimates that only 1% of patients who could benefit from pulmonary rehabilitation programs have suitable access to such programs. A common priority for all informants was that there needed to be greater awareness of—and a more positive orientation to—COPD in both the Australian and health professional communities. The study concluded that substantial reductions in COPD and smoking cessation rates contrast with more limited progress toward adopting other aspects of evidence-based practice. The “good news” story concerning reductions in COPD disease with improving smoking cessation rates could form the basis for suitable media campaigns

Evaluation of the Barwon South Western Region Dementia Strategy

The Department of Health (DH) Barwon-South Western (BSW) Region Dementia Strategy was developed with the support of regional health professionals in response to the Regional, State and National Health Departments’ priority to improve services for people affected by dementia. The National Ageing Research Institute (NARI) was commissioned by DH BSW in 2010 to conduct an evaluation of the BSW Region Dementia Strategy

A Refined Method for Quantitation of Divalent Metal Ions in Metalloproteins and Local Stability and Conformational Heterogeneity of Amyotrophic Lateral Sclerosis-Associated Cu, Zn Superoxide Dismutase

Amyotrophic lateral sclerosis (ALS) is a devastating and progressive disease that results in selective death of motor neurons in the cortex, brain stem and spinal cord. ALS is the most common adult onset motor neuron disease resulting in paralysis and death, commonly within 2 – 5 years of symptom onset, yet there remains no effective treatment for the disease. The majority of ALS cases show no hereditary link (referred to as sporadic ALS or sALS); however, ~10% of cases show a dominant pattern of inheritance (referred to as familial ALS or fALS). Over 170 different mutations in human Cu, Zn superoxide dismutase (SOD1) have been identified to account for ~20% of fALS. SOD1 is a ubiquitously expressed homodimeric antioxidant enzyme. It is widely accepted that mutations in SOD1 result in a gain of toxic function, rather than a loss of native function. A prominent hypothesis for the gain of function is the formation of protein aggregates, which have been shown to be toxic to motor neurons. Protein aggregation is observed in a number of neurodegenerative disorders, including Alzheimer’s, Huntington’s and Parkinson’s disease. Each β-rich monomer of SOD1 binds one catalytic Cu ion and one structural Zn ion. The metallation state of SOD1 significantly influences the structure, dynamics, activity, stability, and aggregation propensity. A similar trend has been observed in a number of metalloenzymes and as such a method to rapidly and accurately quantitate metal ions in proteins is of great importance. Here a review of previous methods using the chromogenic chelator PAR to quantitate metal ions in proteins is presented. Three methods are assessed for their accuracy, precision and ease of use. The methods vary in accuracy, which is highest only under the specific conditions it was designed for. A robust new method is presented here that uses spectral decomposition software to accurately resolve the absorption bands of Cu and Zn with high precision. This method may be successful as a more general method for metal analysis of proteins allowing for the quantitation of additional metal combinations (e.g. Zn/Co, Ni/Cu, Ni/Co). Thermodynamic stability has widely been implicated as playing a major role in the aggregation of globular proteins. Metal loss significantly decreases the global stability of SOD1 and as such metal-depleted (apo) forms of SOD1 have largely been the focus of SOD1 investigations. Recent studies, however, suggest that complete global unfolding is not required for protein aggregation. Local unfolding has been investigated and proposed to be sufficient to induce irreversible protein aggregation in the absence of global destabilization. Enhanced local unfolding has been observed in a number of disease-related proteins. Since SOD1 aggregation may occur from partially unfolded forms, NMR temperature dependence studies have been carried out on the most abundant form of SOD1 in vivo, the fully metallated (holo) dimer, to provide a residue specific picture of subglobal structural changes in SOD1 upon heating. Amide proton (N1H) temperature coefficients report on the hydrogen bonding status of a protein. A curved N1H temperature dependence indicates that the proton populates an alternative conformation generally within 5 kcal/mol of the ground state. NMR temperature dependence studies of pseudoWT indicate that the thermal unfolding process of holo pWT begins with “fraying” of the structure at its periphery. In particular, increased disorder is observed in edge strands β5 and β6, as well as surrounding the zinc binding site. The local stability and conformational heterogeneity of ALS-associated mutants G93A, E100G and V148I was also assessed. All mutants display similar local unfolding patterns to pseudoWT, but also show distinct differences in the hydrogen bonding network surrounding the mutation site. Interestingly, each mutation regardless of its structural context results in altered dynamics at the β-barrel plug, a key stabilizing element in SOD1. A significant proportion of residues (~30%) access alternative states in both pseudoWT and mutants, however, overall mutants appear to be able to access higher free energy alternative states compared to pseudoWT. The implications of these results for the mechanism of protein aggregation and disease are discussed.1 yea

How do case managers spend time on their functions and activities?

Background: Case management has been a widely accepted approach to practice in various care settings. This study aimed to explore how community aged care case managers allocated their time to case management functions, how frequently they performed specific case management activities, and what factors influenced the frequency of their activities. Methods: The study involved 154 survey participants, or 17.1 % of the target case managers in the State of Victoria, Australia. Key information collected included participants’ socio-demographic characteristics, proportions of time allocated to six core case management functions, and frequency ratings of 41 specific activities within seven case management functions. Ordinal regression analyses were performed to determine significant factors associated with participants’ frequency ratings of their activities. Results: Participants allocated the largest proportion of time to care coordination (22.0 %), and the smallest proportion of time to outcome evaluation (8.0 %). Over 70 % of the participants assigned high frequency ratings to 31 of the 41 case management activities. The remaining ten activities, including all four outcome evaluation activities, three needs assessment activities, one care planning activity, one care coordination activity, and one general functions-related activity were less commonly performed very frequently. The regression analyses indicated that some case manager and client factors were significantly associated with frequency ratings of nine of the ten activities aforementioned. The two main findings of the regression analyses were: First, emphasising achieving more case management goals was significantly associated with higher frequency of three outcome evaluation activities; second, longer work experience was significantly associated with higher frequency of one care coordination activity and one outcome evaluation activity. Conclusions: The frequent performance of most case management activities and relative absence of factors influencing their frequency suggest a uniformity of practice in community aged care case managers’ practice. What is not clear is whether the frequency of these activities (in particular less frequent performance of outcome evaluation activities) conforms to expectations

Evaluation Of Innovative Dementia Programmes: A Short Review

Dementia patients are now surviving longer than they did 30 years ago. The result is that in the absence of a cure, carers have to come up with increasingly innovative solutions to the management and treatment of dementia and its behavioural manifestations. This working paper focuses on the social and behavioural techniques used to manage dementia, and discusses alternative ways to evaluate these techniques. Five main attributes of dementia programmes are reviewed: the use of physical design to ameliorate symptoms; communication and the significance of interpersonal relationships; activity programmes; segregated care; and behaviour modification techniques. Finally, alternative models of evaluation programmes are discussed

How to Assess the Quality of Long Term Care

This working paper reviews three methods of assessing the quality of long term care for the aged. The three methods are as follows. First, in criterion-guided assessment, a largely subjective assessment is made, using a set of guidelines as a framework for the assessment. These guidelines are a list of criteria which define the aspects of care which are important. Second, assessment may be made using structured assessment protocols which may include completion of written questionnaires. Structured assessment procedures concentrate on assessment of individuals living in the facility, or consist of a more general assessment of the 'personality' of the facility. Third, assessment may be based on selected key indicators which are assumed to reflect the level of quality of care found in other unmeasured areas as well, or they are used as markers for more intensive investigation. This method is a shorthand summary of the overall quality, and is used either alone or in conjunction with more detailed assessments. These methods are reviewed here with particular reference to the method of assessing quality of long term care that is used by the Australian federal government. After reviewing the literature, the policy implications of the review, and future directions for research in this field are discussed