Microwave-Assisted Extraction of Brewers' Spent Grain Arabinoxylans

Brewers´ spent grain (BSG) is a by-product from beer industry that can be exploited as a source of arabinoxylo-oligosaccharides (AXOS) with prebiotic activity. In this study, microwave-assisted extractions were performed during 2 min at 140-210°Cin order to evaluate the feasibility of this extraction technology for quantitative extraction of the arabinoxylans (AX) or AXOS from BSG. The AX yield increasedwith the increase of the temperature in the range used. The best condition of extraction of the AXwas 210 ºC during 2 min, allowing the extraction of 43% of total AX. These AX showed structural variability which allow to define specific types of compounds for different applications and uses depending on the extraction conditions used

Factor VIIa administration in traumatic brain injury: an AAST-MITC propensity score analysis.

Background:Recombinant factor VIIa (rFVIIa) has been used off-label as an adjunct in the reversal of warfarin therapy and management of hemorrhage after trauma. Only a handful of these reports are rigorous studies, from which results regarding safety and effectiveness have been mixed. There remains no clear consensus as to the role of rFVIIa in traumatic brain injury (TBI). Methods:Eleven level 1 trauma centers provided clinical data and head CT scans of patients with a Glasgow Coma Scale (GCS) score of ≤13 and radiographic evidence of TBI. A propensity score (PS) to receive rFVIIa in those surviving ≥2 days was calculated for each patient based on patient demographics, comorbidities, physiology, Injury Severity Score, admission GCS score, and treatment center. Patients receiving rFVIIa within 24 hours of admission were matched to patients who did not receive rFVIIa for outcomes assessment. Subgroup analysis evaluated patients with primary head injury with PS matching. Results:There were 4284 patient observations; 129 received rFVIIa. Groups were comparable after matching. No differences in mortality or morbidity were found. Improvement in GCS score from admission to discharge was less among those receiving rFVIIa (5.5 vs. 2.4; P value 0.001); however, there was no difference in average GCS score at discharge. No significant differences in outcomes were identified in patients with isolated TBI receiving rFVIIa. Discussion:rFVIIa in early management of TBI is not associated with a decreased risk of mortality or morbidity, and may negatively impact recovery and functional status at discharge in the severely injured patient with polytrauma. Level of evidence:Level III. Study type:Therapeutic/care management

Gravity with extra dimensions and dark matter interpretation: Phenomenological example via Miyamoto-Nagai galaxy

A configuration whose density profile coincides with the Newtonian potential for spiral galaxies is constructed from a 4D isotropic metric plus extra dimensional components. A Miyamoto-Nagai ansatz is used to solve Einstein equations. The stable rotation curves of such system are computed and, without fitting techniques, we recover with accuracy the observational data for flat or not asymptotically flat galaxy rotation curves. The density profiles are reconstructed and compared to that obtained from the Newtonian potential.Comment: 10 pages, 10 figures, submitted to Brazilian Journal of Physic

A Challenging Abdominal Pain

info:eu-repo/semantics/publishedVersio

New species of Xestoleberididae (Crustacea, Ostracoda) from Archipelago of São Pedro and São Paulo, Equatorial Atlantic

Two new species of Xestoleberididae: Xestoleberis brasilinsularis sp. nov. and Xestoleberis machadoae sp. nov., both endemic to Archipelago of São Pedro and São Paulo, are described. The record of these shallow marine waters species from Brazilian oceanic islands represents an important contribution to the knowledge of the evolutionary history the species inhabit areas

Effects of oxygen depletion on soot production, emission and radiative heat transfer in opposed-flow flame spreading over insulated wire in microgravity

This paper investigates experimentally and numerically pressure effects on soot production and radiative heat transfer in non-buoyant opposed-flow flames spreading over wires coated by Low Density PolyEthylene (LPDE). Experiments, conducted in parabolic flights, consider pressure levels ranging from 50.7 kPa to 121.6 kPa and an oxidizer flowing parallel to the wire's axis at a velocity of 150 mm/s and composed of 20% O2/80% N2 in volume. The numerical model includes a detailed chemistry, a two-equation smoke-point based soot production model, a radiation model coupling the Full-Spectrum correlated-k method with the finite volume method and a simple degradation model for LDPE. An analysis of the experimental data shows that the spread rate, the pyrolysis mass flow rate, and the residence time for soot formation are independent of pressure whereas the soot formation rate is third-order in pressure. The model reproduces quantitatively the effects of pressure on soot production and captures the transition from non-smoking to smoking flames. The radiant fraction increases with pressure because of an enhancement in soot radiation whereas the contribution of radiating gases remains approximately constant over the range of pressures considered. In addition, gas radiation dominates at pressure lower than 75 kPa whereas soot radiation prevails at higher-pressure levels. Consistently with the data obtained at normal gravity, the smoke-point transition is found to occur for a radiant fraction of about 0.3 and the soot oxidation freezing temperature is estimated in the range 1350-1450K. Eventually, whatever the pressure considered, the surface re-radiation from the wire is higher than the incident radiative flux from the flame to the surface along the entire wire. This shows that radiative heat transfer contributes negatively to the heating of the unburnt LDPE and to the heat balance along the pyrolysing surface

Pneumatosis Coli Treated with Metronidazole and Hyperbaric Oxygen Therapy: A Successful Case

A pneumatose intestinal, caracterizada pela presença de gás na parede do cólon, é uma condição incomum com um espectro de apresentação variável. Pode ser idiopática ou secundária a outras doenças. A tomografia computorizada é o método de diagnóstico com maior sensibilidade. Na ausência de sinais e sintomas sugestivos de complicações, como a perfuração e a peritonite, a pneumatose intestinal pode ser tratada de forma conservadora. Apresenta-se o caso de uma mulher de 59 anos com pneumatose cólica secundária a teratoma ovárico benigno. Após a cirurgia, manteve-se sintomática e foi tratada com sucesso com metronidazol e oxigenoterapia hiperbárica