374 research outputs found

    Inclusive Scholarship: Developing Black Studies in the United States

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    Brings together four reports commissioned between 1982 and 2000 that examine the history of African American Studies, its impact, and its institutionalization. Reviews Ford's grantmaking to African American Studies programs from 1982 to 2007

    Chlorpromazine for schizophrenia: a Cochrane systematic review of 50 years of randomised controlled trials

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    BACKGROUND: Chlorpromazine (CPZ) remains one of the most common drugs used for people with schizophrenia worldwide, and a benchmark against which other treatments can be evaluated. Quantitative reviews are rare; this one evaluates the effects of chlorpromazine in the treatment of schizophrenia in comparison with placebo. METHODS: We sought all relevant randomised controlled trials (RCT) comparing chlorpromazine to placebo by electronic and reference searching, and by contacting trial authors and the pharmaceutical industry. Data were extracted from selected trials and, where possible, synthesised and random effects relative risk (RR), the number needed to treat (NNT) and their 95% confidence intervals (CI) calculated. RESULTS: Fifty RCTs from 1955–2000 were included with 5276 people randomised to CPZ or placebo. They constitute 2008 person-years spent in trials. Meta-analysis of these trials showed that chlorpromazine promotes a global improvement (n = 1121, 13 RCTs, RR 0.76 CI 0.7 to 0.9, NNT 7 CI 5 to 10), although a considerable placebo response is also seen. People allocated to chlorpromazine tended not to leave trials early in both the short (n = 945, 16 RCTs, RR 0.74 CI 0.5 to 1.1) and medium term (n = 1861, 25 RCTs, RR 0.79 CI 0.6 to 1.1). There were, however, many adverse effects. Chlorpromazine is sedating (n = 1242, 18 RCTs, RR 2.3 CI 1.7 to 3.1, NNH 6 CI 5 to 8), increases a person's chances of experiencing acute movement disorders, Parkinsonism and causes low blood pressure with dizziness and dry mouth. CONCLUSION: It is understandable why the World Health Organization (WHO) have endorsed and included chlorpromazine in their list of essential drugs for use in schizophrenia. Low- and middle-income countries may have more complete evidence upon which to base their practice compared with richer nations using recent innovations

    Validating attention bias as a novel measure of affect in sheep

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    To facilitate the understanding and enhancement of animal well-being in livestock production systems, there is a need to develop robust methods which can assess the emotional or affective states of animals, as an aspect of their welfare. Chapter 1 of this thesis discusses some current methods used for the assessment of animal affect, highlighting the key limitations of each approach. The potential role of cognitive methods for welfare assessment is introduced, with a particular focus on attention bias tests. The aim of this thesis was to further develop and validate a novel attention bias test for the assessment of affective states in sheep. Chapter 2 examines the impact of pharmacologically-induced stress on judgement bias and attention bias in sheep. The study finds no clear indication that elevated cortisol concentrations impacted on cognitive biases in sheep. Chapter 3 refines the attention bias test methodology to remove a habituation period, improving the practical application of the test. The study demonstrates that pharmacologically-induced anxiety-like and calm-like states impact on attention bias in sheep. Chapter 4 introduces a modified method for the assessment of attention bias, which is shown to assess and differentiate pharmacologically-induced anxiety-like and depression-like states in sheep. Chapter 5 examines the potential influence of pharmacologically induced positive affective states on the modified attention bias test, finding no clear effect of positive states on attention bias in sheep. It is suggested that external factors may have confounded results of this study. Chapter 6 examines repeatability of the attention bias test to gain insight into the factors influencing animal behaviour during the attention bias test. Key measures of attention had low repeatability and are suggested to be readily influenced by emotions and moods. Measures of vigilance and zones crossed had moderate repeatability and are suggested to be more heavily influenced by temperament or personality traits. Finally, chapter 7 concludes that the attention bias test developed throughout this thesis may be a useful and practical tool for the assessment of negative affective states in sheep

    Chlorpromazine versus placebo for schizophrenia

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    Adolescents Becoming Feminist on Twitter: New Literacies Practices, Commitments, and Identity Work

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    The author investigated the relation between young people\u27s new literacies practices and identity development on Twitter and found that participants used three new literacies practices (live‐tweeting, hashtagging, and information sharing) in unique ways to develop feminist identities in this social media space. Participants mobilized popular culture to initiate dialogue about feminist issues, such as the wage gap, to participate in social activism (e.g., advocating for women\u27s reproductive care), and to provide informal counsel to peers. Twitter can be a vital space for young people to become feminists, providing opportunities to learn, develop, and participate

    Digital methods for ethnography: analytical concepts for ethnographers exploring social media environments

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    The aim of this article is to introduce some analytical concepts suitable for ethnographers dealing with social media environments. As a result of the growth of social media, the Internet structure has become a very complex, fluid, and fragmented space. Within this space, it is not always possible to consider the 'classical' online community as the privileged field site for the ethnographer, in which s/he immerses him/herself. Differently, taking inspiration from some methodological principles of the Digital Methods paradigm, I suggest that the main task for the ethnographer moving across social media environments should not be exclusively that of identifying an online community to delve into but of mapping the practices through which Internet users and digital devices structure social formations around a focal object (e.g., a brand). In order to support the ethnographer in the mapping of social formations within social media environments, I propose five analytical concepts: community, public, crowd, self-presentation as a tool, and user as a device

    Green Mind Theory: How Brain-Body-Behaviour Links into Natural and Social Environments for Healthy Habits

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    We propose a Green Mind Theory (GMT) to link the human mind with the brain and body, and connect the body into natural and social environments. The processes are reciprocal: environments shape bodies, brains, and minds; minds change body behaviours that shape the external environment. GMT offers routes to improved individual well-being whilst building towards greener economies. It builds upon research on green exercise and nature-based therapies, and draws on understanding derived from neuroscience and brain plasticity, spiritual and wisdom traditions, the lifeways of original cultures, and material consumption behaviours. We set out a simple metaphor for brain function: a bottom brain stem that is fast-acting, involuntary, impulsive, and the driver of fight and flight behaviours; a top brain cortex that is slower, voluntary, the centre for learning, and the driver of rest and digest. The bottom brain reacts before thought and directs the sympathetic nervous system. The top brain is calming, directing the parasympathetic nervous system. Here, we call the top brain blue and the bottom brain red; too much red brain is bad for health. In modern high-consumption economies, life has often come to be lived on red alert. An over-active red mode impacts the gastrointestinal, immune, cardiovascular, and endocrine systems. We develop our knowledge of nature-based interventions, and suggest a framework for the blue brain-red brain-green mind. We show how activities involving immersive-attention quieten internal chatter, how habits affect behaviours across the lifecourse, how long habits take to be formed and hard-wired into daily practice, the role of place making, and finally how green minds could foster prosocial and greener economies. We conclude with observations on twelve research priorities and health interventions, and ten calls to action

    Margarita de Sossa, Sixteenth-Century Puebla de los Ángeles, New Spain (Mexico)

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    Margarita de Sossa’s freedom journey was defiant and entrepreneurial. In her early twenties, still enslaved in Portugal, she took possession of her body; after refusing to endure her owner’s sexual demands, he sold her, and she was transported to Mexico. There, she purchased her freedom with money earned as a healer and then conducted an enviable business as an innkeeper. Sossa’s biography provides striking insights into how she conceptualized freedom in terms that included – but was not limited to – legal manumission. Her transatlantic biography offers a rare insight into the life of a free black woman (and former slave) in late sixteenth-century Puebla, who sought to establish various degrees of freedom for herself. Whether she was refusing to acquiesce to an abusive owner, embracing entrepreneurship, marrying, purchasing her own slave property, or later using the courts to petition for divorce. Sossa continued to advocate on her own behalf. Her biography shows that obtaining legal manumission was not always equivalent to independence and autonomy, particularly if married to an abusive husband, or if financial successes inspired the envy of neighbors
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