Avaliação de margens cirúrgicas e prevalência de neoplasias mamárias em cadelas: um estudo retrospectivo

Na cirurgia de remoção de neoplasias mamárias a obtenção de margens livres é importante para predizer a eficácia do procedimento. O objetivo deste estudo foi avaliar a relação das margens com os achados clínicos e histopatológicos de cadelas com neoplasia mamária submetidas à exérese cirúrgica. Foi realizado um estudo retrospectivo, no período de 2016 à 2020, de 169 cadelas diagnosticadas com neoplasia mamária maligna, onde foram obtidas informações quanto: avaliação das margens, localização, tamanho, apresentação clínica, grau de aderência, graduação e classificação histopatológica das neoplasias e o comprometimento de linfonodos regionais. As margens estavam comprometidas em 11 (6,5%) pacientes. As neoplasias malignas mais frequentes foram carcinoma em tumor misto (n=83; 29,64%). Pacientes com carcinoma anaplásico (n=6; 2,14%) apresentaram mais probabilidade de ter as margens comprometidas (p= 0,050), e os pacientes com adenomioepitelioma maligno (n=13; 100%), maiores chances de apresentarem as margens livres (p=0,021). Os pacientes que apresentaram os linfonodos com metástases, possuíram mais chance de as margens estarem comprometidas (p=0.041). Podemos concluir que os achados histopatológicos possuem relação com as margens cirúrgicas, enquanto os parâmetros clínicos como: localização, o tamanho, a apresentação não interferiram. Nesse estudo os pacientes acometidos com carcinomas anaplásicos apresentam uma maior chance de as margens estarem comprometidas, enquanto os acometidos por adenomioepitelioma maligno tenderam a apresentar as margens cirúrgicas livres de neoplasia

Avaliação de margens cirúrgicas e prevalência de neoplasias mamárias em cadelas: um estudo retrospectivo

In surgery for removal of mammary neoplasms, the achievement of free margins is important to predict the effectiveness of the procedure. The aim of this study was to evaluate the relationship between margins and clinical and histopathological findings in bitches with mammary neoplasms submitted to surgical excision. A retrospective study was conducted from 2016 to 2020, of 170 bitches diagnosed with malignant mammary neoplasia, where information was obtained regarding: evaluation of the margins, location, size, clinical presentation, degree of adhesion, degree and histopathological classification of neoplasms and the involvement of regional lymph nodes. Margins were compromised in 11 (6.5%) patients. The most frequent malignant neoplasms were mixed tumor carcinoma (n=83, 29.64%). Patients with anaplastic carcinoma (n=6, 2.14%) were more likely to have compromised margins (p= 0.050), and patients with malignant adenomyoepithelioma (n=13, 100%), more likely to have free margins (p=0.021). Patients who had lymph nodes with metastases were more likely to have compromised margins (p=0.041). We can conclude that the histopathological findings are related to surgical margins, while the clinical parameters evaluated, such as location, size and presentation did not interfere. Patients affected with anaplastic carcinomas had a greater chance of having compromised margins, while those affected by malignant adenomyoepithelioma tended to have surgical margins free of neoplasia.Na cirurgia de remoção de neoplasias mamárias a obtenção de margens livres é importante para predizer a eficácia do procedimento. O objetivo deste estudo foi avaliar a relação das margens com os achados clínicos e histopatológicos de cadelas com neoplasia mamária submetidas à exérese cirúrgica. Foi realizado um estudo retrospectivo, no período de 2016 à 2020, de 169 cadelas diagnosticadas com neoplasia mamária maligna, onde foram obtidas informações quanto: avaliação das margens, localização, tamanho, apresentação clínica, grau de aderência, graduação e classificação histopatológica das neoplasias e o comprometimento de linfonodos regionais. As margens estavam comprometidas em 11 (6,5%) pacientes. As neoplasias malignas mais frequentes foram carcinoma em tumor misto (n=83; 29,64%). Pacientes com carcinoma anaplásico (n=6; 2,14%) apresentaram mais probabilidade de ter as margens comprometidas (p= 0,050), e os pacientes com adenomioepitelioma maligno (n=13; 100%), maiores chances de apresentarem as margens livres (p=0,021). Os pacientes que apresentaram os linfonodos com metástases, possuíram mais chance de as margens estarem comprometidas (p=0.041). Podemos concluir que os achados histopatológicos possuem relação com as margens cirúrgicas, enquanto os parâmetros clínicos como: localização, o tamanho, a apresentação não interferiram. Nesse estudo os pacientes acometidos com carcinomas anaplásicos apresentam uma maior chance de as margens estarem comprometidas, enquanto os acometidos por adenomioepitelioma maligno tenderam a apresentar as margens cirúrgicas livres de neoplasia

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Evaluation of surgical margins as a prognostic factor in mammary tumors in bitches and study of the feeling of mourning of tutors after the loss of pets

One of the neoplasms that occur most frequently in dogs is mammary neoplasia, which may have an unfavorable prognosis and lead the animal to death. Two studies were carried out, the first study with the objective of evaluating the relationship between surgical margins and the clinical and histopathological findings of female dogs with mammary neoplasia, and the second study aimed to obtain information about the feelings and what is the impact on the lives of the tutors , when facing the period of illness and death of their pets. In order to carry out the study on surgical margins, data were obtained through a retrospective study of patients treated at HCV UFPel, from 2016 to 2020, collecting patient review data, as well as clinical and histopathological information. 181 medical records were obtained and of these, 170 were recorded. It was observed that patients affected with anaplastic carcinomas have a greater chance of the margins being compromised, while those affected by malignant adenomyoepithelioma tended to have surgical margins free of neoplasia. For the second study, information was obtained through an online questionnaire, about the feeling of the tutors during the period of illness and/or death of the pets. 418 questionnaires were answered by tutors, and more than 70% (295) of the participants reported that both the period of illness and death were difficult periods, for most respondents their pet was like a child 294 (70,33 %). We conclude that the histopathological findings are related to the surgical margins, while the evaluated clinical parameters, such as: location, size, presentation did not interfere. Patients with anaplastic carcinomas are more likely to have the margins compromised, while those with malignant adenomyoepithelioma tend to have tumor-free surgical margins. We also concluded that when the loss of pets occurs, guardians have feelings similar to those of the loss of a human being, and we emphasize that during the period of illness, guardians are affected by feelings similar to those of when humans face terminal illnesses, characterizing anticipatory grief.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESUma das neoplasias que ocorrem com maior frequência em cães é a neoplasia mamária, podendo ter um prognóstico desfavorável, e levar o animal a óbito., com isso quando ocorre a perda de um animal, se tem um grande impacto emocional. Foram realizados dois estudos, o primeiro estudo com o objetivo de avaliar a relação das margens cirúrgicas com os achados clínicos e histopatológicos de cadelas com neoplasia mamária, e o segundo estudo teve por objetivo obter informações sobre os sentimentos e qual o impacto na vida dos tutores, ao enfrentar o período de doença e da morte dos seus animais de estimação. Para a realização do estudo sobre as margens cirúrgicas, foram obtidos dados através de um estudo retrospectivo em pacientes atendidos no HCV UFPel, no período de 2016 a 2020, sendo coletados dados de resenha dos pacientes, assim como informações clínicas e histopatológicas. Foram obtidos 181 prontuários e destes, 170 foram contabilizados, foi observado que os pacientes acometidos com carcinomas anaplásicos apresentam uma maior chance de as margens estarem comprometidas, enquanto os acometidos por adenomioepitelioma maligno tenderam a apresentar as margens cirúrgicas livres de neoplasia. Para o segundo estudo foram obtidas informações através de um questionário online, sobre o sentimento dos tutores durante o período da doença e/ou morte dos animais de estimação. Foram respondidos 418 questionários por tutores, e mais de 70% (295) dos participantes relataram que tanto o período da doença quanto a morte foram períodos difíceis, para a maioria dos entrevistados o seu animal de estimação era como um filho 294 (70,33%). Concluímos que, os achados histopatológicos possuem relação com as margens cirúrgicas, enquanto os parâmetros clínicos avaliados, como: localização, o tamanho, a apresentação não interferiram. Os pacientes acometidos com carcinomas anaplásicos apresentam uma maior chance de as margens estarem comprometidas, enquanto os acometidos por adenomioepitelioma maligno tenderam a apresentar as margens cirúrgicas livres de neoplasia. Concluímos também que quando ocorre a perda dos animais de estimação, os tutores têm sentimentos semelhantes aos da perda de um ser humano, e destacamos que durante o período da doença, os tutores são acometidos por sentimentos semelhantes aos de quando humanos enfrentam doenças terminais, caracterizando o luto antecipatório

Avaliação clínica e histopatológica das neoplasias mamárias em gatas

O objetivo analisar os achados clínicos e histopatológicos de felinas com neoplasia mamária submetidas à exérese cirúrgica, através de estudo retrospectivo em pacientes atendidas no Hospital de Clínicas Veterinárias da Universidade Federal de Pelotas (HCV-UFPel), no período de 2016 à 2020