319 research outputs found
Culture, Conformity, and Emotional Suppression in Online Reviews
In this study, we examine consumers’ cultural background as an antecedent of online review characteristics. We theoretically propose and empirically examine the effect of cultural background (specifically individualism (versus collectivism)) on consumers’ tendency to conform to prior opinion and review texts’ emotionality. We also examine how conformity and emotionality relate to review helpfulness. We test our hypotheses using a unique dataset that combines online restaurant reviews from TripAdvisor with measures of individualism/collectivism values. We found that consumers from a collectivist culture were less likely to deviate from the average prior rating and to express emotion in their reviews. Moreover, individuals perceived those reviews that exhibited high conformity and intense emotions to be less helpful. We also present several important implications for managing online review platforms in light of these findings, which reflect the previously unidentified drivers of systematic differences in the characteristics of online reviews
Percutaneous Nephrolithotomy under Local Infiltration Anesthesia in Kneeling Prone Position for a Patient with Spinal Deformity
Urolithiasis, a common condition in patients with spinal deformity, poses a challenge to surgical procedures and anesthetic management. A 51-year-old Chinese male presented with bilateral complex renal calculi. He was also affected by severe kyphosis deformity and spinal stiffness due to ankylosing spondylitis. Dr. Li performed the percutaneous nephrolithotomy under local infiltration anesthesia with the patient in a kneeling prone position, achieving satisfactory stone clearance with no severe complications. We found this protocol safe and effective to manage kidney stones in patients with spinal deformity. Local infiltration anesthesia may benefit patients for whom epidural anesthesia and intubation anesthesia are difficult
A Novel Prognostic Predictor of Immune Micro-environment and Therapeutic Response in Kidney Renal Clear Cell Carcinoma based on Necroptosis-related Gene Signature
Background: Necroptosis, a cell death of caspase-independence, plays a pivotal role in cancer biological regulation. Although necroptosis is closely associated with oncogenesis, cancer metastasis, and immunity, there remains a lack of studies determining the role of necroptosis-related genes (NRGs) in the highly immunogenic cancer type, kidney renal clear cell carcinoma (KIRC). Methods: The information of clinicopathology and transcriptome was extracted from TCGA database. Following the division into the train and test cohorts, a three-NRGs (TLR3, FASLG, ZBP1) risk model was identified in train cohort by LASSO regression. The overall survival (OS) comparison was conducted between different risk groups through Kaplan-Meier analysis, which was further validated in test cohort. The Cox proportional hazards regression model was introduced to assess its impact of clinicopathological factors and risk score on survival. ESTIMATE and CIBERSORT algorithms were introduced to evaluate immune microenvironment, while enrichment analysis was conducted to explore the biological significance. Correlation analysis was applied for the correlation assessment between checkpoint gene expression and risk score, between gene expression and therapeutic response. Gene expressions from TCGA were verified by GEO datasets and immunohistochemistry (IHC) analysis. Results: This NRGs-related signature predicted poorer OS in high-risk group, which was also verified in test cohort. Risk score could also independently predict survival outcome of KIRC. Significant changes were also found in immune microenvironment and checkpoint gene expressions between different risk groups, with immune functional enrichment in high-risk group. Interestingly, therapeutic response was correlated with the expressions of NRGs. The expressions of NRGs from TCGA were consistent with those from GEO datasets and IHC analysis. Conclusion: The NRGs-related signature functions as a novel prognostic predictor of immune microenvironment and therapeutic response in KIRC
Improving interface bonding of double-skinned CFST columns
It has been demonstrated that high-strength concrete (HSC) is able to improve the strength-to-weight ratio of reinforced concrete columns and maximise the usable areas of tall buildings. However, closely spaced transverse reinforcement needs to be installed to provide stronger confinement for averting brittle failure of HSC. To resolve the problem, double-skinned concrete-filled-steel-tubular (CFST) columns have been advocated, which eliminates the steel congestion problem for better concrete placing and reduces the concrete arching action thus providing a more uniform confining pressure. Despite these advantages, a major shortcoming of double-skinned CFST columns is that imperfect interface bonding occurs in the elastic stage that reduces elastic strength and stiffness. Thus, the authors proposed to adopt external confinement to restrict the lateral dilation of the outer tube of double-skinned CFST columns. To verify the effectiveness of the proposed external rings, a total of 20 double-skinned normal- and high-strength CFST columns were tested. From the test results, it was observed that the stiffness, axial load-carrying capacity and ductility of ringconfined double-skinned CFST columns were significantly higher than the unconfined columns
Reconstructing human activities via coupling mobile phone data with location-based social networks
In the era of big data, the ubiquity of location-aware portable devices
provides an unprecedented opportunity to understand inhabitants' behavior and
their interactions with the built environments. Among the widely used data
resources, mobile phone data is the one passively collected and has the largest
coverage in the population. However, mobile operators cannot pinpoint one user
within meters, leading to the difficulties in activity inference. To that end,
we propose a data analysis framework to identify user's activity via coupling
the mobile phone data with location-based social networks (LBSN) data. The two
datasets are integrated into a Bayesian inference module, considering people's
circadian rhythms in both time and space. Specifically, the framework considers
the pattern of arrival time to each type of facility and the spatial
distribution of facilities. The former can be observed from the LBSN Data and
the latter is provided by the points of interest (POIs) dataset. Taking
Shanghai as an example, we reconstruct the activity chains of 1,000,000 active
mobile phone users and analyze the temporal and spatial characteristics of each
activity type. We assess the results with some official surveys and a
real-world check-in dataset collected in Shanghai, indicating that the proposed
method can capture and analyze human activities effectively. Next, we cluster
users' inferred activity chains with a topic model to understand the behavior
of different groups of users. This data analysis framework provides an example
of reconstructing and understanding the activity of the population at an urban
scale with big data fusion
Perbandingan Harga Energi dari Sumber Energi Baru Terbarukan dan Fosil
PERBANDINGAN HARGA ENERGI DARI SUMBER ENERGI BARU TERBARUKAN DAN FOSIL. Transportasi biaya rendah untuk orang dan barang sangat penting untuk kesejahteraan ekonomi bangsa. Hingga kini jika harga minyak naik, biaya transportasi otomatis akan mengikuti dan sebagian rakyat menderita akibat melambungnya harga makanan dan barang-barang lainnya. Hampir 100 persen kebutuhan energi transportasi negara Indonesia didukung oleh minyak. Sementara biaya di sektor energi terutama listrik, di negara maju yang juga berperan signifikan untuk mendukung transportasi, jauh lebih stabil dan dapat diprediksi. Kebutuhan energi yang begitu tinggi di sektor transportasi cenderung memaksa manusia untuk mengupayakan sumber dan sarana energi dalam bentuk lain seperti listrik atau hydrogen yang dapat menyamai atau melebihi kinerja bahan bakar minyak. Makalah ini bertujuan untuk menganalisis perbandingan keekonomian harga energi dari sumber EBT dan fosil untuk melihat sejauh mana peluang keekonomian beberapa jenis energi dapat memainkan peran signifikan di sektor transportasi dan dampak selanjutnya di dalam sistem energi. Metodologi yang digunakan adalah penelusuran pustaka dan perhitungan langsung pada bahan atau sumber energi terkait. Dari hasil analisis diperoleh bahwa akan semakin dibutuhkan peran energi nuklir dan energi tertentu lainnya sebagai sumber energi listrik menimbang aspek keekonomiannya yang relatif lebih baik
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